(Q34285768)

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mTOR pathway is activated by PKA in adrenocortical cells and participates in vivo to apoptosis resistance in primary pigmented nodular adrenocortical disease (PPNAD).

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1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

mTOR pathway is activated by PKA in adrenocortical cells and participates in vivo to apoptosis resistance in primary pigmented nodular adrenocortical disease (PPNAD). (English)

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

primary pigmented nodular adrenocortical disease

0 references

Jérôme Bertherat

11

object named as

Jérôme Bertherat

0 references

Anne-Marie Lefrançois-Martinez

9

object named as

Anne-Marie Lefrançois-Martinez

0 references

Isabelle Sahut-Barnola

2

object named as

Isabelle Sahut-Barnola

0 references

Cyrille de Joussineau

1

object named as

Cyrille de Joussineau

0 references

Marie Batisse-Lignier

6

object named as

Marie Batisse-Lignier

0 references

Constantine A Stratakis

10

object named as

Constantine A Stratakis

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

author name string

Frédérique Tissier

3

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Typhanie Dumontet

4

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Coralie Drelon

5

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Igor Tauveron

7

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Jean-Christophe Pointud

8

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Pierre Val

12

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Antoine Martinez

13

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

publication date

27 May 2014

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Human Molecular Genetics

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

23

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

20

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

5418-5428

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Follicular thyroid cancers demonstrate dual activation of PKA and mTOR as modeled by thyroid-specific deletion of Prkar1a and Pten in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184389

6 July 2018

Human chorionic gonadotropin stimulates theca-interstitial cell proliferation and cell cycle regulatory proteins by a cAMP-dependent activation of AKT/mTORC1 signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184389

6 July 2018

Cushing's syndrome and fetal features resurgence in adrenal cortex-specific Prkar1a knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184389

6 July 2018

cAMP-dependent activation of mammalian target of rapamycin (mTOR) in thyroid cells. Implication in mitogenesis and activation of CDK4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184389

6 July 2018

Inactivation of the Carney complex gene 1 (protein kinase A regulatory subunit 1A) inhibits SMAD3 expression and TGF beta-stimulated apoptosis in adrenocortical cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184389

6 July 2018

Identification of cAMP-dependent kinase as a third in vivo ribosomal protein S6 kinase in pancreatic beta-cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184389

6 July 2018

Depletion of type IA regulatory subunit (RIalpha) of protein kinase A (PKA) in mammalian cells and tissues activates mTOR and causes autophagic deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184389

6 July 2018

The deficiency of Akt1 is sufficient to suppress tumor development in Pten+/- mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184389

6 July 2018

A genome-wide scan identifies mutations in the gene encoding phosphodiesterase 11A4 (PDE11A) in individuals with adrenocortical hyperplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184389

6 July 2018

Adrenocorticotropin-dependent changes in SF-1/DAX-1 ratio influence steroidogenic genes expression in a novel model of glucocorticoid-producing adrenocortical cell lines derived from targeted tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184389

6 July 2018

PI3K/Akt/mTOR pathway as a target for cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184389

6 July 2018

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184389

6 July 2018

Decreased expression of cyclic adenosine monophosphate-regulated aldose reductase (AKR1B1) is associated with malignancy in human sporadic adrenocortical tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184389

6 July 2018

Activin induces x-zone apoptosis that inhibits luteinizing hormone-dependent adrenocortical tumor formation in inhibin-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184389

6 July 2018

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184389

6 July 2018

p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184389

6 July 2018

Mutations in the protein kinase A R1alpha regulatory subunit cause familial cardiac myxomas and Carney complex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184389

6 July 2018

Mutations of the gene encoding the protein kinase A type I-alpha regulatory subunit in patients with the Carney complex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184389

6 July 2018

Regulation of BAD by cAMP-dependent protein kinase is mediated via phosphorylation of a novel site, Ser155

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184389

6 July 2018

https://api.crossref.org/works/10.1093%2FHMG%2FDDU265

21 January 2018

Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184389

6 July 2018

Loss of expression of the ubiquitous transcription factor cAMP response element-binding protein (CREB) and compensatory overexpression of the activator CREMtau in the human adrenocortical cancer cell line H295R.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184389

6 July 2018

Proliferation and apoptosis in the human adrenal cortex during the fetal and perinatal periods: implications for growth and remodeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184389

6 July 2018

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184389

6 July 2018

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184389

6 July 2018

Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184389

6 July 2018

The complex of myxomas, spotty pigmentation, and endocrine overactivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184389

6 July 2018

Mutations in cyclic AMP-dependent protein kinase and corticotropin (ACTH)-sensitive adenylate cyclase affect adrenal steroidogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184389

6 July 2018

Mutation in PDE8B, a cyclic AMP-specific phosphodiesterase in adrenal hyperplasia

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDU265

21 January 2018

Dual hormonal regulation of endocrine tissue mass and vasculature by adrenocorticotropin in the adrenal cortex.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDU265

21 January 2018

A PRKAR1A mutation associated with primary pigmented nodular adrenocortical disease in 12 kindreds

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDU265

21 January 2018

PRKAR1A Mutations and protein kinase A interactions with other signaling pathways in the adrenal cortex.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDU265

21 January 2018

mTOR signaling, function, novel inhibitors, and therapeutic targets.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184389

28 October 2018

Bilateral primary pigmented nodular adrenocortical disease. Rare cause of the Cushing syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184389

28 October 2018

Cutaneous myxomas. A major component of the complex of myxomas, spotty pigmentation, and endocrine overactivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/24865460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A

1 reference

https://pubmed.ncbi.nlm.nih.gov/24865460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

mTOR kinase and the regulatory subunit of protein kinase A (PRKAR1A) spatially and functionally interact during autophagosome maturation

1 reference

https://pubmed.ncbi.nlm.nih.gov/24865460

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/HMG/DDU265

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

ResearchGate publication ID

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