(Q34303405)

1 August 2017

Programmed cell death pathways in cancer: a review of apoptosis, autophagy and programmed necrosis (English)

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1 August 2017

0 references

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1

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14 May 2020

author name string

Z Shi

2

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14 May 2020

S Zhao

3

1 reference

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14 May 2020

F-T Wang

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496669&resulttype=core&format=json

14 May 2020

T-T Zhou

5

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14 May 2020

B Liu

6

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14 May 2020

J-K Bao

7

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14 May 2020

publication date

3 October 2012

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1 August 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496669&resulttype=core&format=json

14 May 2020

volume

45

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496669&resulttype=core&format=json

14 May 2020

issue

6

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14 May 2020

page(s)

487-498

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496669&resulttype=core&format=json

Hallmarks of Cancer: The Next Generation

14 May 2020

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Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

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Life and death partners: apoptosis, autophagy and the cross-talk between them

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Autophagic pathways as new targets for cancer drug development

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Necroptosis: an emerging form of programmed cell death

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Genetic control of necrosis - another type of programmed cell death

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Four deaths and a funeral: from caspases to alternative mechanisms.

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Cell death pathology: cross-talk with autophagy and its clinical implications

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Crosstalk between autophagy and apoptosis in the regulation of paclitaxel-induced cell death in v-Ha-ras-transformed fibroblasts

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Core signaling pathways of survival/death in autophagy-related cancer networks

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Deconvoluting the context-dependent role for autophagy in cancer

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Autophagy: basic principles and relevance to disease

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Cell death by necrosis: towards a molecular definition

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Alkylating DNA damage stimulates a regulated form of necrotic cell death

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Regulatory pathways in photodynamic therapy induced apoptosis.

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The apoptosis/autophagy paradox: autophagic vacuolization before apoptotic death

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Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

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Necrostatin-1 reverts shikonin-induced necroptosis to apoptosis

21 January 2018

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Dysregulation of TNFα-induced necroptotic signaling in chronic lymphocytic leukemia: suppression of CYLD gene by LEF1.

21 January 2018

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Targeting the extrinsic apoptosis signaling pathway for cancer therapy

21 January 2018

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Fas-induced caspase denitrosylation

21 January 2018

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FADD and caspase-8 control the outcome of autophagic signaling in proliferating T cells

21 January 2018

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Apoptosis and oncogenesis: give and take in the BCL-2 family

21 January 2018

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BH3-only proteins: Orchestrators of apoptosis

21 January 2018

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Caspase-mediated programmed cell death pathways as potential therapeutic targets in cancer

21 January 2018

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Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

21 January 2018

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 January 2018

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The role of Bcl-2 and its pro-survival relatives in tumourigenesis and cancer therapy

21 January 2018

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Apoptosis and cancer: mutations within caspase genes

21 January 2018

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Two CD95 (APO-1/Fas) signaling pathways

21 January 2018

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Initiator caspases in apoptosis signaling pathways

21 January 2018

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Caspases and kinases in a death grip

21 January 2018

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Conversation between apoptosis and autophagy: "Is it your turn or mine?".

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Recruitment, activation and retention of caspases-9 and -3 by Apaf-1 apoptosome and associated XIAP complexes

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Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

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Protein kinase A regulates caspase-9 activation by Apaf-1 downstream of cytochrome c.

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NF-kappaB: linking inflammation and immunity to cancer development and progression

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Oscillations in NF-kappaB signaling control the dynamics of gene expression

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NFkappaB mediates apoptosis through transcriptional activation of Fas (CD95) in adenoviral hepatitis

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The IKK NF-kappa B system: a treasure trove for drug development

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The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta

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Cell growth inhibition and induction of apoptosis by snake venom toxin in ovarian cancer cell via inactivation of nuclear factor κB and signal transducer and activator of transcription 3.

21 January 2018

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Pachymic acid impairs breast cancer cell invasion by suppressing nuclear factor-κB-dependent matrix metalloproteinase-9 expression.

21 January 2018

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PUMA mediates the apoptotic response to p53 in colorectal cancer cells

21 January 2018

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MicroRNA regulation of core apoptosis pathways in cancer.

21 January 2018

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21 January 2018

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MicroRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1

21 January 2018

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Virally induced cellular microRNA miR-155 plays a key role in B-cell immortalization by Epstein-Barr virus

21 January 2018

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MicroRNA and cancer--focus on apoptosis

21 January 2018

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Causes and consequences of microRNA dysregulation in cancer

21 January 2018

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Let-7a microRNA suppresses therapeutics-induced cancer cell death by targeting caspase-3.

21 January 2018

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Therapeutic potential for microRNAs

21 January 2018

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Tor-mediated induction of autophagy via an Apg1 protein kinase complex

21 January 2018

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FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells

21 January 2018

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Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy

21 January 2018

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The double-edged sword of autophagy modulation in cancer

21 January 2018

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Cancer. Addiction to oncogenes--the Achilles heal of cancer

21 January 2018

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Mechanisms of disease: Oncogene addiction--a rationale for molecular targeting in cancer therapy

21 January 2018

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Targeting the PI3K-AKT-mTOR pathway: progress, pitfalls, and promises

21 January 2018

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The PI3K inhibitor arsenal: choose your weapon!

21 January 2018

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Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma

21 January 2018

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Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control

21 January 2018

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Activation of B-Raf kinase requires phosphorylation of the conserved residues Thr598 and Ser601.

21 January 2018

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Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex

21 January 2018

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Targeting the Raf kinase cascade in cancer therapy--novel molecular targets and therapeutic strategies

21 January 2018

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The Ras protein superfamily: evolutionary tree and role of conserved amino acids

21 January 2018

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GTPases and T cell activation

21 January 2018

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DRAM, a p53-induced modulator of autophagy, is critical for apoptosis

21 January 2018

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Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

21 January 2018

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The atypical PKC-interacting protein p62 is an important mediator of RANK-activated osteoclastogenesis.

21 January 2018

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p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling

21 January 2018

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Stimulation of autophagy by the p53 target gene Sestrin2.

21 January 2018

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Regulation of autophagy by cytoplasmic p53

21 January 2018

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PUMA, a novel proapoptotic gene, is induced by p53

21 January 2018

1 reference

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Regulation and function of FoxO transcription factors in normal and cancer stem cells: what have we learned?

21 January 2018

1 reference

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Heat shock protein 90-mediated inactivation of nuclear factor-κB switches autophagy to apoptosis through becn1 transcriptional inhibition in selenite-induced NB4 cells

21 January 2018

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Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis

21 January 2018

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Hsp90 regulates processing of NF-kappa B2 p100 involving protection of NF-kappa B-inducing kinase (NIK) from autophagy-mediated degradation.

21 January 2018

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NF-kappaB activation represses tumor necrosis factor-alpha-induced autophagy

21 January 2018

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MicroRNA-modulated autophagic signaling networks in cancer

21 January 2018

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Vesicle-mediated protein transport: regulatory interactions between the Vps15 protein kinase and the Vps34 PtdIns 3-kinase essential for protein sorting to the vacuole in yeast

21 January 2018

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Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae

21 January 2018

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The evolutionarily conserved domain of Beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function

21 January 2018

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Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG

21 January 2018

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Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis

21 January 2018

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21 January 2018

The Beclin 1 interactome

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Anti- and pro-tumor functions of autophagy

21 January 2018

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RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis

21 January 2018

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Sequential activation of poly(ADP-ribose) polymerase 1, calpains, and Bax is essential in apoptosis-inducing factor-mediated programmed necrosis.

21 January 2018

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Poly(ADP-ribose) polymerase-1 signaling to mitochondria in necrotic cell death requires RIP1/TRAF2-mediated JNK1 activation

21 January 2018

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The molecular "Jekyll and Hyde" duality of PARP1 in cell death and cell survival

21 January 2018

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TNF-induced activation of the Nox1 NADPH oxidase and its role in the induction of necrotic cell death

21 January 2018

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Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation

21 January 2018

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Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha

21 January 2018

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Absence of oncogenic mutations of RAS family genes in soft tissue sarcomas of 100 Japanese patients.

21 January 2018

1 reference

12 December 2020

Necroptosis: a specialized pathway of programmed necrosis

1 reference

12 December 2020

A systems biology view of cancer

1 reference

12 December 2020

Participation of p53 protein in the cellular response to DNA damage

1 reference

12 December 2020

Formation of large molecular weight fragments of DNA is a key committed step of apoptosis in thymocytes.

1 reference

12 December 2020

Apoptosis, Bcl-2 family proteins and caspases: the ABCs of seizure-damage and epileptogenesis?

1 reference

12 December 2020

Ras recruits Raf-1 to the plasma membrane for activation by tyrosine phosphorylation

1 reference

12 December 2020

Autophagy is a therapeutic target in anticancer drug resistance.

1 reference

12 December 2020

p53-dependent pathways of apoptosis

1 reference

12 December 2020

Targeting apoptosis pathways in cancer therapy

1 reference

12 December 2020

Understanding the Role of the Death Receptor 5/FADD/caspase-8 Death Signaling in Cancer Metastasis

1 reference

12 December 2020

Tumour suppressor PTEN enhanced enzyme activity of GPx, SOD and catalase by suppression of PI3K/AKT pathway in non-small cell lung cancer cell lines

1 reference

12 December 2020

1 reference

12 December 2020

10.1111/J.1365-2184.2012.00845.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496669&resulttype=core&format=json

14 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496669&resulttype=core&format=json

14 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496669&resulttype=core&format=json