(Q34310069)

English

VEGF/VEGFR-2 upregulates EZH2 expression in lung adenocarcinoma cells and EZH2 depletion enhances the response to platinum-based and VEGFR-2-targeted therapy

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

VEGF/VEGFR-2 upregulates EZH2 expression in lung adenocarcinoma cells and EZH2 depletion enhances the response to platinum-based and VEGFR-2-targeted therapy (English)

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

Ignacio I Wistuba

14

object named as

Ignacio I Wistuba

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

12

object named as

John Heymach

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

11

object named as

Waun Ki Hong

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Europe PubMed Central

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1 August 2017

author name string

Erick Riquelme

1

1 reference

Europe PubMed Central

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1 August 2017

Milind Suraokar

2

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Carmen Behrens

3

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Heather Y Lin

4

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Luc Girard

5

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Monique B Nilsson

6

1 reference

Europe PubMed Central

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1 August 2017

George Simon

7

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Europe PubMed Central

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1 August 2017

Jing Wang

8

1 reference

Europe PubMed Central

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1 August 2017

Kevin R Coombes

9

1 reference

Europe PubMed Central

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1 August 2017

J Jack Lee

10

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Europe PubMed Central

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1 August 2017

John D Minna

13

1 reference

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1 August 2017

language of work or name

0 references

publication date

21 May 2014

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Europe PubMed Central

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1 August 2017

Clinical Cancer Research

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Europe PubMed Central

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1 August 2017

20

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Europe PubMed Central

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1 August 2017

14

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

3849-3861

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4190586/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Human lung epithelial cells progressed to malignancy through specific oncogenic manipulations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190586

6 July 2018

The VEGF pathway in cancer and disease: responses, resistance, and the path forward.

1 reference

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6 July 2018

Epigenetic therapy with 3-deazaneplanocin A, an inhibitor of the histone methyltransferase EZH2, inhibits growth of non-small cell lung cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190586

6 July 2018

Polycomb repressor complex-2 is a novel target for mesothelioma therapy

1 reference

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6 July 2018

Enhancer of zeste homolog 2 is a novel prognostic biomarker in nonsmall cell lung cancer

1 reference

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6 July 2018

FGF-2 regulates cell proliferation, migration, and angiogenesis through an NDY1/KDM2B-miR-101-EZH2 pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190586

6 July 2018

Increased VEGFR-2 gene copy is associated with chemoresistance and shorter survival in patients with non-small-cell lung carcinoma who receive adjuvant chemotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190586

6 July 2018

Polycomb protein EZH2 regulates cancer cell fate decision in response to DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190586

6 July 2018

Pharmacologic disruption of Polycomb Repressive Complex 2 inhibits tumorigenicity and tumor progression in prostate cancer

1 reference

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6 July 2018

MEK-ERK pathway regulates EZH2 overexpression in association with aggressive breast cancer subtypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190586

6 July 2018

miR-101 is down-regulated in glioblastoma resulting in EZH2-induced proliferation, migration, and angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190586

6 July 2018

Down-regulation of miR-101 in endothelial cells promotes blood vessel formation through reduced repression of EZH2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190586

6 July 2018

MicroRNA-101 exerts tumor-suppressive functions in non-small cell lung cancer through directly targeting enhancer of zeste homolog 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190586

6 July 2018

EZH2 promotes expansion of breast tumor initiating cells through activation of RAF1-β-catenin signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190586

6 July 2018

Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190586

6 July 2018

Regulation of tumor angiogenesis by EZH2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190586

6 July 2018

MicroRNA-101 negatively regulates Ezh2 and its expression is modulated by androgen receptor and HIF-1alpha/HIF-1beta

1 reference

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Collateral damage: toxic effects of targeted antiangiogenic therapies in ovarian cancer

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Signatures of polycomb repression and reduced H3K4 trimethylation are associated with p15INK4b DNA methylation in AML.

1 reference

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6 July 2018

Polycomb protein EZH2 regulates E2F1-dependent apoptosis through epigenetically modulating Bim expression

1 reference

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6 July 2018

Assessment of tumour hypoxia for prediction of response to therapy and cancer prognosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190586

6 July 2018

Functional significance of VEGFR-2 on ovarian cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190586

6 July 2018

miR-296 regulates growth factor receptor overexpression in angiogenic endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190586

6 July 2018

Repression of E-cadherin by the polycomb group protein EZH2 in cancer

1 reference

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6 July 2018

Enhancer of zeste homolog 2 downregulates E-cadherin by mediating histone H3 methylation in gastric cancer cells

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Biology of HIF-1alpha

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The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190586

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The 2004 World Health Organization classification of lung tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190586

6 July 2018

EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer

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EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190586

6 July 2018

VEGF-receptor signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190586

6 July 2018

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Sphingosine kinase mediates vascular endothelial growth factor-induced activation of ras and mitogen-activated protein kinases

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The polycomb group protein EZH2 is involved in progression of prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190586

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1 reference

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6 July 2018

VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells

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Effects of angiogenesis inhibitors on multistage carcinogenesis in mice

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Expression of vascular endothelial growth factor mRNA in non-small-cell lung carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4190586

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Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

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Small GTP-Binding Protein Rac Is an Essential Mediator of Vascular Endothelial Growth Factor-Induced Endothelial Fenestrations and Vascular Permeability

1 reference

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based on heuristic

inferred from PubMed ID database lookup

Enhancement of pleural dissemination and lymph node metastasis of intrathoracic lung cancer cells by vascular endothelial growth factors (VEGFs)

1 reference

https://pubmed.ncbi.nlm.nih.gov/24850841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular endothelial growth factor, p53, Rb, Bcl-2 expression and response to chemotherapy in advanced non-small cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/24850841

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based on heuristic

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[Tumor hypoxia:advantage or disadvantage?]

1 reference

https://pubmed.ncbi.nlm.nih.gov/24850841

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/1078-0432.CCR-13-1916

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

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