(Q34316343)

1 August 2017

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title

Thrombosis as an intravascular effector of innate immunity (English)

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1 August 2017

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2

Steffen Massberg

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1 August 2017

Bernd Engelmann

1

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1 August 2017

7 December 2012

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Nature Reviews Immunology

1 August 2017

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1 August 2017

13

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1 August 2017

1

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1 August 2017

34-45

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Heart disease and stroke statistics--2011 update: a report from the American Heart Association

1 August 2017

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Pulmonary embolism and deep vein thrombosis

31 March 2020

1 reference

Basic mechanisms and pathogenesis of venous thrombosis

31 March 2020

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Triggers, targets and treatments for thrombosis

31 March 2020

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Coagulation, an ancestral serine protease cascade, exerts a novel function in early immune defense.

31 March 2020

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Coagulation systems of invertebrates and vertebrates and their roles in innate immunity: the same side of two coins?

31 March 2020

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Insect hemolymph clotting

31 March 2020

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Insect hemolymph clotting: evidence for interaction between the coagulation system and the prophenoloxidase activating cascade.

31 March 2020

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The coagulation of insect hemolymph.

31 March 2020

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Intravascular immunity: the host-pathogen encounter in blood vessels.

31 March 2020

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Mechanisms of thrombus formation

31 March 2020

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Dynamic Visualization of Thrombopoiesis Within Bone Marrow

31 March 2020

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Delivering new insight into the biology of megakaryopoiesis and thrombopoiesis

31 March 2020

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A crucial role of glycoprotein VI for platelet recruitment to the injured arterial wall in vivo

31 March 2020

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Multiple integrin-ligand interactions synergize in shear-resistant platelet adhesion at sites of arterial injury in vivo.

31 March 2020

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Platelet glycoprotein V binds to collagen and participates in platelet adhesion and aggregation

31 March 2020

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Glycoprotein Ibalpha and von Willebrand factor in primary platelet adhesion and thrombus formation: lessons from mutant mice

31 March 2020

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Localization of tissue factor in the normal vessel wall and in the atherosclerotic plaque

31 March 2020

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The interactions between inflammation and coagulation

31 March 2020

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Exposure of platelet membrane phosphatidylserine regulates blood coagulation

31 March 2020

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Protease-activated receptors in hemostasis, thrombosis and vascular biology

31 March 2020

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Leukocyte accumulation promoting fibrin deposition is mediated in vivo by P-selectin on adherent platelets

31 March 2020

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Platelets and the immune continuum

31 March 2020

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Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo.

31 March 2020

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Anti-P-selectin antibody decreases inflammation and thrombus formation in venous thrombosis

31 March 2020

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Mechanisms of venous thrombosis and resolution

31 March 2020

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Getting to the site of inflammation: the leukocyte adhesion cascade updated

31 March 2020

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von Willebrand factor-mediated platelet adhesion is critical for deep vein thrombosis in mouse models

31 March 2020

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Dendritic cell PAR1-S1P3 signalling couples coagulation and inflammation

31 March 2020

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TREM-1 ligand expression on platelets enhances neutrophil activation

31 March 2020

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Atherosclerosis: current pathogenesis and therapeutic options

31 March 2020

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Platelets in defense against bacterial pathogens

31 March 2020

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Long-term antithrombotic protection by in vivo depletion of platelet glycoprotein VI in mice

31 March 2020

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Deficiency or inhibition of Gas6 causes platelet dysfunction and protects mice against thrombosis.

31 March 2020

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Arterial thrombosis--insidious, unpredictable and deadly

31 March 2020

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The Endotoxin-induced Coagulant Activity of Human Monocytes

31 March 2020

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Intravascular tissue factor initiates coagulation via circulating microvesicles and platelets.

31 March 2020

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Blood-borne tissue factor: another view of thrombosis

31 March 2020

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Tissue factor-positive neutrophils bind to injured endothelial wall and initiate thrombus formation

31 March 2020

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Human polymorphonuclear leukocytes produce and express functional tissue factor upon stimulation.

31 March 2020

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Eosinophils are a major intravascular location for tissue factor storage and exposure

31 March 2020

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Platelet-associated tissue factor contributes to the collagen-triggered activation of blood coagulation

31 March 2020

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Protein disulfide isomerase inhibitors constitute a new class of antithrombotic agents

31 March 2020

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Neutrophil extracellular traps kill bacteria

31 March 2020

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The humoral pattern recognition receptor PTX3 is stored in neutrophil granules and localizes in extracellular traps

31 March 2020

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Human peptidoglycan recognition protein S is an effector of neutrophil-mediated innate immunity

31 March 2020

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Defect in neutrophil killing and increased susceptibility to infection with nonpathogenic gram-positive bacteria in peptidoglycan recognition protein-S (PGRP-S)-deficient mice.

31 March 2020

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Extracellular DNA traps promote thrombosis.

31 March 2020

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Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases.

31 March 2020

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Oxidation of a specific methionine in thrombomodulin by activated neutrophil products blocks cofactor activity. A potential rapid mechanism for modulation of coagulation

31 March 2020

1 reference

Extracellular histones are mediators of death through TLR2 and TLR4 in mouse fatal liver injury

31 March 2020

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Extracellular histones are major mediators of death in sepsis

31 March 2020

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Extracellular histones promote thrombin generation through platelet-dependent mechanisms: involvement of platelet TLR2 and TLR4

31 March 2020

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The effect of inflammation on coagulation and vice versa

31 March 2020

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Experimental study of physical factors, including fibrin formation, influencing the spread of fluids and small particles within and from the peritoneal cavity of the dog

31 March 2020

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Fibrin-mediated protection against infection-stimulated immunopathology

31 March 2020

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Roles for thrombin and fibrin(ogen) in cytokine/chemokine production and macrophage adhesion in vivo

31 March 2020

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Leukocyte engagement of fibrin(ogen) via the integrin receptor alphaMbeta2/Mac-1 is critical for host inflammatory response in vivo

31 March 2020

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Fibrin and fibrinolysis in infection and host defense

31 March 2020

1 reference

Coagulation and innate immune responses: can we view them separately?

31 March 2020

1 reference

Protective roles for fibrin, tissue factor, plasminogen activator inhibitor-1, and thrombin activatable fibrinolysis inhibitor, but not factor XI, during defense against the gram-negative bacterium Yersinia enterocolitica

31 March 2020

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LPS induction of gene expression in human monocytes

31 March 2020

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Direct evidence for Hageman factor (factor XII) activation by bacterial lipopolysaccharides (endotoxins).

31 March 2020

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Extracellular RNA constitutes a natural procoagulant cofactor in blood coagulation

31 March 2020

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Extracellular histones increase plasma thrombin generation by impairing thrombomodulin-dependent protein C activation.

31 March 2020

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Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood

31 March 2020

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Novel anti-bacterial activities of β-defensin 1 in human platelets: suppression of pathogen growth and signaling of neutrophil extracellular trap formation.

31 March 2020

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Platelets and the innate immune system: mechanisms of bacterial-induced platelet activation

31 March 2020

1 reference

Platelet Toll-like receptor expression modulates lipopolysaccharide-induced thrombocytopenia and tumor necrosis factor-alpha production in vivo

31 March 2020

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Platelet-bound lipopolysaccharide enhances Fc receptor-mediated phagocytosis of IgG-opsonized platelets

31 March 2020

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Reduced thromboxane biosynthesis in carriers of toll-like receptor 4 polymorphisms in vivo

31 March 2020

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Lipopolysaccharide from enterohemorrhagic Escherichia coli binds to platelets through TLR4 and CD62 and is detected on circulating platelets in patients with hemolytic uremic syndrome

31 March 2020

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Lipopolysaccharide stimulates platelet secretion and potentiates platelet aggregation via TLR4/MyD88 and the cGMP-dependent protein kinase pathway

31 March 2020

1 reference

A platelet-mediated system for shuttling blood-borne bacteria to CD8α+ dendritic cells depends on glycoprotein GPIb and complement C3

31 March 2020

1 reference

Complement inhibition decreases the procoagulant response and confers organ protection in a baboon model of Escherichia coli sepsis

31 March 2020

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Complement and coagulation: strangers or partners in crime?

31 March 2020

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Platelets, complement, and contact activation: partners in inflammation and thrombosis

31 March 2020

1 reference

The contact system--a novel branch of innate immunity generating antibacterial peptides

31 March 2020

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Restoration of NET formation by gene therapy in CGD controls aspergillosis

31 March 2020

1 reference

Innate immunity: an overview

31 March 2020

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Fibrinolysis and host response in bacterial infections

31 March 2020

1 reference

Plasminogen is a critical host pathogenicity factor for group A streptococcal infection

31 March 2020

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DNase expression allows the pathogen group A Streptococcus to escape killing in neutrophil extracellular traps

31 March 2020

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An endonuclease allows Streptococcus pneumoniae to escape from neutrophil extracellular traps

31 March 2020

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Contribution of coagulases towards Staphylococcus aureus disease and protective immunity

31 March 2020

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Two distinct coagulase-dependent barriers protect Staphylococcus aureus from neutrophils in a three dimensional in vitro infection model

31 March 2020

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Hematopoietic and nonhematopoietic cell tissue factor activates the coagulation cascade in endotoxemic mice

31 March 2020

1 reference

Platelets, neutrophils, and neutrophil extracellular traps (NETs) in sepsis

31 March 2020

1 reference

Current theories on the pathophysiology of multiple organ failure after trauma

31 March 2020

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Platelet polyphosphates are proinflammatory and procoagulant mediators in vivo

31 March 2020

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Hematopoietic cell-derived microparticle tissue factor contributes to fibrin formation during thrombus propagation

31 March 2020

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Accumulation of tissue factor into developing thrombi in vivo is dependent upon microparticle P-selectin glycoprotein ligand 1 and platelet P-selectin

31 March 2020

1 reference

Targeting coagulation factor XII provides protection from pathological thrombosis in cerebral ischemia without interfering with hemostasis

31 March 2020

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Defective thrombus formation in mice lacking coagulation factor XII

31 March 2020

1 reference

Neutrophil extracellular traps promote deep vein thrombosis in mice

31 March 2020

1 reference

Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis

31 March 2020

1 reference

SLE in 2011: Deciphering the role of NETs and networks in SLE.

31 March 2020

1 reference

Thrombosis and embolism after injury

31 March 2020

1 reference

12 December 2020

Tissue factor de-encryption: ionophore treatment induces changes in tissue factor activity by phosphatidylserine-dependent and -independent mechanisms

1 reference

12 December 2020

Protein disulfide isomerase acts as an injury response signal that enhances fibrin generation via tissue factor activation

1 reference

12 December 2020

Intravascular tissue factor pathway--a model for rapid initiation of coagulation within the blood vessel

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12 December 2020

Interaction of pathogens with the endothelium.

1 reference

12 December 2020

A critical role for extracellular protein disulfide isomerase during thrombus formation in mice

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12 December 2020

Plasma thrombomodulin in health and diseases.

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12 December 2020

Identifiers

DOI

10.1038/NRI3345

1 reference

1 August 2017

1 reference

PubMed ID

23222502