(Q34316470)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22731403%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

title

Three-in-one agonists for PPAR-α, PPAR-γ, and PPAR-δ from traditional Chinese medicine (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22731403%20AND%20SRC:MED&resulttype=core&format=json

traditional Chinese medicine

6 February 2020

main subject

1 reference

based on heuristic

inferred from title

object named as

traditional Chinese medicine

17 February 2024

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22731403%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Yongjiang Wu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22731403%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

author name string

Kuan-Chung Chen

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22731403%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Su-Sen Chang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22731403%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Hung-Jin Huang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22731403%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Calvin Yu-Chian Chen

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22731403%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

publication date

26 June 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22731403%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biomolecular Structure and Dynamics

6 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22731403%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

volume

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22731403%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22731403%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

page(s)

662-683

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22731403%20AND%20SRC:MED&resulttype=core&format=json

Scaffold-based discovery of indeglitazar, a PPAR pan-active anti-diabetic agent

6 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

PPAR-β/δ agonists for Type 2 diabetes and dyslipidemia: an adopted orphan still looking for a home

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

CHARMM: A program for macromolecular energy, minimization, and dynamics calculations

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Docking simulation and competitive experiments validate the interaction between the 2,5-xylidine inhibitor and Rigidoporus lignosus laccase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

In silico pharmacology suggests ginger extracts may reduce stroke risks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

High performance screening, structural and molecular dynamics analysis to identify H1 inhibitors from TCM Database@Taiwan

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Two birds with one stone? Possible dual-targeting H1N1 inhibitors from traditional Chinese medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Key features for designing phosphodiesterase-5 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Screening from the world's largest TCM database against H1N1 virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Lose weight with traditional chinese medicine? Potential suppression of fat mass and obesity-associated protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Peroxisome proliferator-activated receptor translational research and clinical experience

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Computational screening and design of traditional Chinese medicine (TCM) to block phosphodiesterase-5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Virtual screening and drug design for PDE-5 receptor from traditional Chinese medicine database

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

TCM Database@Taiwan: the world's largest traditional Chinese medicine database for drug screening in silico

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Discovery of potent inhibitors for phosphodiesterase 5 by virtual screening and pharmacophore analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Traditional Chinese medicine, a solution for reducing dual stroke risk factors at once?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Insights into designing the dual-targeted HER2/HSP90 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Investigation into potent inflammation inhibitors from traditional Chinese medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Docking studies on the binding of quinoline derivatives and hematin to Plasmodium falciparum lactate dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

PPARalpha and dyslipidemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Peroxisome proliferator-activated receptor-gamma: from adipogenesis to carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Discovery of a novel selective PPARgamma modulator from (-)-Cercosporamide derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

PPARdelta is pro-tumorigenic in a mouse model of COX-2-induced mammary cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Peroxisome proliferator-activated receptor family and its relationship to renal complications of the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Design of new chemotherapeutics against the deadly anthrax disease. Docking and molecular dynamics studies of inhibitors containing pyrrolidine and riboamidrazone rings on nucleoside hydrolase from Bacillus anthracis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Peroxisome proliferator-activated receptors: bridging metabolic syndrome with molecular nutrition

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Inducible nitric oxide synthase and cyclooxygenase-2 participate in anti-inflammatory activity of imperatorin from Glehnia littoralis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

A novel strategy for designing the selective PPAR agonist by the "sum of activity" model

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Molecular docking studies to map the binding site of squalene synthase inhibitors on dehydrosqualene synthase of Staphylococcus aureus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

The peroxisome proliferator-activated receptor alpha regulates amino acid metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Discovery of an oxybenzylglycine based peroxisome proliferator activated receptor alpha selective agonist 2-((3-((2-(4-chlorophenyl)-5-methyloxazol-4-yl)methoxy)benzyl)(methoxycarbonyl)amino)acetic acid (BMS-687453)

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

7-Chloroarctinone-b as a new selective PPARgamma antagonist potently blocks adipocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

T2384, a novel antidiabetic agent with unique peroxisome proliferator-activated receptor gamma binding properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Potent inhibitor design against H1N1 swine influenza: structure-based and molecular dynamics analysis for M2 inhibitors from traditional Chinese medicine database

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Study on interaction of DNA from calf thymus with 1,10-phenanthrolinehexyldithiocarbamatopalladium(II) nitrate as potential antitumor agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

International Union of Pharmacology. LXI. Peroxisome proliferator-activated receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Human and rat peroxisome proliferator activated receptors (PPARs) demonstrate similar tissue distribution but different responsiveness to PPAR activators

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Compounds of the 1,5-di(4-R-phenyl)- 3-selenopentanediones-1,5 series interaction with the basidiomycete Lentinula edodes lectins: computations and experiment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor beta(delta)

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Structure validation by Calpha geometry: phi,psi and Cbeta deviation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Review: Peroxisome proliferator-activated receptor gamma and adipose tissue--understanding obesity-related changes in regulation of lipid and glucose metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Adipose-specific effect of rosiglitazone on vascular permeability and protein kinase C activation: novel mechanism for PPARgamma agonist's effects on edema and weight gain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Fluid retention mediated by renal PPARgamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Search for novel remedies to augment radiation resistance of inhabitants of Fukushima and Chernobyl disasters: identifying DNA repair protein XRCC4 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

LigandFit: a novel method for the shape-directed rapid docking of ligands to protein active sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Peroxisome-Proliferator-Activated Receptor δ Activates Fat Metabolism to Prevent Obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Ligand-activated peroxisome proliferator-activated receptor-gamma protects against ischemic cerebral infarction and neuronal apoptosis by 14-3-3 epsilon upregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Cyclooxygenase inhibitors induce colon cancer cell apoptosis Via PPARdelta --> 14-3-3epsilon pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Pharmacophore modeling and hybrid virtual screening for the discovery of novel IκB kinase 2 (IKK2) inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Molecular recognition of fatty acids by peroxisome proliferator-activated receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Identification of potent EGFR inhibitors from TCM Database@Taiwan

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

Peroxisome proliferator-activated receptor structures: ligand specificity, molecular switch and interactions with regulators.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

A novel perspective on designing the inhibitor of HER2 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2012.689699

10.1080/07391102.2012.689699

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22731403%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

1 reference