(Q34320238)

English

IL-27 structural analysis demonstrates similarities with ciliary neurotrophic factor (CNTF) and leads to the identification of antagonistic variants

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scholarly article

1 reference

Europe PubMed Central

1 August 2017

IL-27 structural analysis demonstrates similarities with ciliary neurotrophic factor (CNTF) and leads to the identification of antagonistic variants (English)

1 reference

Europe PubMed Central

1 August 2017

author name string

Francois Rousseau

1

1 reference

Europe PubMed Central

1 August 2017

Laetitia Basset

2

1 reference

Europe PubMed Central

1 August 2017

Josy Froger

3

1 reference

Europe PubMed Central

1 August 2017

Nathalie Dinguirard

4

1 reference

Europe PubMed Central

1 August 2017

Sylvie Chevalier

5

1 reference

Europe PubMed Central

1 August 2017

Hugues Gascan

6

1 reference

Europe PubMed Central

1 August 2017

language of work or name

0 references

publication date

25 October 2010

1 reference

Europe PubMed Central

1 August 2017

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

1 August 2017

107

1 reference

Europe PubMed Central

1 August 2017

45

1 reference

Europe PubMed Central

1 August 2017

19420-19425

1 reference

Europe PubMed Central

1 August 2017

The IL-27 p28 subunit binds cytokine-like factor 1 to form a cytokine regulating NK and T cell activities requiring IL-6R for signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

Interleukin 27: a double-edged sword for offense and defense

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

Structural Organization of a Full-Length gp130/LIF-R Cytokine Receptor Transmembrane Complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

Ciliary neurotrophic factor, cardiotrophin-like cytokine, and neuropoietin share a conserved binding site on the ciliary neurotrophic factor receptor alpha chain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

The structure of interleukin-23 reveals the molecular basis of p40 subunit sharing with interleukin-12

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

The biology and therapeutic potential of interleukin 27.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

Discovery and biology of IL-23 and IL-27: related but functionally distinct regulators of inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

Inactivation of cardiotrophin-like cytokine, a second ligand for ciliary neurotrophic factor receptor, leads to cold-induced sweating syndrome in a patient

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

Two different contact sites are recruited by cardiotrophin-like cytokine (CLC) to generate the CLC/CLF and CLC/sCNTFRalpha composite cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

Neuropoietin, a new IL-6-related cytokine signaling through the ciliary neurotrophic factor receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

IL-27 regulates IL-12 responsiveness of naive CD4+ T cells through Stat1-dependent and -independent mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

Characterization of a potent human interleukin-11 agonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

Hexameric structure and assembly of the interleukin-6/IL-6 alpha-receptor/gp130 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

Cutting Edge: Role of IL-27/WSX-1 Signaling for Induction of T-Bet Through Activation of STAT1 During Initial Th1 Commitment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

New perspectives on the design of cytokines and growth factors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

Development of Th1-type immune responses requires the type I cytokine receptor TCCR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

CLF associates with CLC to form a functional heteromeric ligand for the CNTF receptor complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

Charged residues dominate a unique interlocking topography in the heterodimeric cytokine interleukin-12

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

Receptor recognition by gp130 cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

Definition of receptor binding sites on human interleukin-11 by molecular modeling-guided mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

Novel neurotrophin-1/B cell-stimulating factor-3: a cytokine of the IL-6 family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

The immunoglobulin-like module of gp130 is required for signaling by interleukin-6, but not by leukemia inhibitory factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

Gp130 and the interleukin-6 family of cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

Identification of ciliary neurotrophic factor (CNTF) residues essential for leukemia inhibitory factor receptor binding and generation of CNTF receptor antagonists.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

A novel interleukin-12 p40-related protein induced by latent Epstein-Barr virus infection in B lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

Immunohistochemical localization of ciliary neurotrophic factor receptor alpha expression in the rat nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

The alpha component of the CNTF receptor is required for signaling and defines potential CNTF targets in the adult and during development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

Purification, cloning, and expression of ciliary neurotrophic factor (CNTF).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

Structural design and molecular evolution of a cytokine receptor superfamily

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

https://api.crossref.org/works/10.1073%2FPNAS.1005793107

21 January 2018

Neuropoietic cytokines in the hematopoietic fold

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

Human growth hormone and extracellular domain of its receptor: crystal structure of the complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

Conversion of human interleukin-4 into a high affinity antagonist by a single amino acid replacement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

6 July 2018

Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1005793107

21 January 2018

Cutting edge: a key pathogenic role of IL-27 in T cell- mediated hepatitis.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1005793107

21 January 2018

WSX-1: a key role in induction of chronic intestinal nematode infection

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1005793107

21 January 2018

WSX-1 is required for resistance to Trypanosoma cruzi infection by regulation of proinflammatory cytokine production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984150

28 October 2018

Antagonist design through forced electrostatic mismatch

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1005793107

21 January 2018

Analysis of the human interleukin-6/human interleukin-6 receptor binding interface at the amino acid level: proposed mechanism of interaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/20974977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A bioactive designer cytokine for human hematopoietic progenitor cell expansion

1 reference

https://pubmed.ncbi.nlm.nih.gov/20974977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

WSX-1 is required for the initiation of Th1 responses and resistance to L. major infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/20974977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential transcription of the mouse acute phase serum amyloid A genes in response to pro-inflammatory cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/20974977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The IL-27 receptor (WSX-1) is an inhibitor of innate and adaptive elements of type 2 immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20974977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Released form of CNTF receptor alpha component as a soluble mediator of CNTF responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/20974977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of functional receptor epitopes on the structure of ciliary neurotrophic factor indicates a conserved, function-related epitope topography among helical cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/20974977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-27 signaling compromises control of bacterial growth in mycobacteria-infected mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20974977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/20974977

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.1005793107

1 reference

Europe PubMed Central

1 August 2017

2010PNAS..10719420R

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1 reference

Europe PubMed Central

1 August 2017

1 reference

Europe PubMed Central

1 August 2017

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