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Gene therapy for pancreatic cancer--current and prospective strategies.
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Europe PubMed Central
PubMed publication ID
11476989
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11476989%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
review article
1 reference
stated in
Europe PubMed Central
title
Gene therapy for pancreatic cancer--current and prospective strategies
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11476989
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11476989%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
main subject
gene therapy
0 references
author
John P Neoptolemos
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11476989
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11476989%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
Eithne Costello
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11476989
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11476989%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
author name string
C M Halloran
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11476989
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11476989%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
P Ghaneh
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11476989
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11476989%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
publication date
1 December 2000
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11476989
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11476989%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
published in
Surgical Oncology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11476989
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11476989%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
volume
9
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11476989
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11476989%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
issue
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11476989
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11476989%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
page(s)
181-191
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11476989
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11476989%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
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7 January 2021
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Therapy of locally unresectable pancreatic carcinoma: a randomized comparison of high dose (6000 rads) radiation alone, moderate dose radiation (4000 rads + 5-fluorouracil), and high dose radiation + 5-fluorouracil: The Gastrointestinal Tumor Study
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Further evidence of effective adjuvant combined radiation and chemotherapy following curative resection of pancreatic cancer. Gastrointestinal Tumor Study Group
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Adjuvant radiotherapy and 5-fluorouracil after curative resection of cancer of the pancreas and periampullary region: phase III trial of the EORTC gastrointestinal tract cancer cooperative group
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7 January 2021
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DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1
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7 January 2021
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K-ras oncogene subtype mutations are associated with survival but not expression of p53, p16(INK4A), p21(WAF-1), cyclin D1, erbB-2 and erbB-3 in resected pancreatic ductal adenocarcinoma
1 reference
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Crossref
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7 January 2021
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Transforming growth factor alpha and epidermal growth factor in human pancreatic cancer
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Crossref
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7 January 2021
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Enhanced expression of transforming growth factor beta isoforms in pancreatic cancer correlates with decreased survival
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7 January 2021
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bax, but not bcl-2, influences the prognosis of human pancreatic cancer
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Crossref
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https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
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7 January 2021
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Moderate activation of the apoptosis inhibitor bcl-xL worsens the prognosis in pancreatic cancer
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
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7 January 2021
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Feeding dendritic cells with tumor antigens: self-service buffet or à la carte?
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7 January 2021
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ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents
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7 January 2021
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Gene therapy: the first decade
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Crossref
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https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cancer gene therapy: hard lessons and new courses
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Role of viral antigens in destructive cellular immune responses to adenovirus vector-transduced cells in mouse lungs.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
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7 January 2021
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inferred from DOI database lookup
Gene therapy: trials and tribulations
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
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7 January 2021
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inferred from DOI database lookup
Retroviral vectors
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Crossref
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https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
A safe packaging line for gene transfer: separating viral genes on two different plasmids
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
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7 January 2021
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inferred from DOI database lookup
Safe and efficient generation of recombinant retroviruses with amphotropic and ecotropic host ranges
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Crossref
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https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
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7 January 2021
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inferred from DOI database lookup
Human gene therapy
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Crossref
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7 January 2021
based on heuristic
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Self-inactivating retroviral vectors designed for transfer of whole genes into mammalian cells
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Crossref
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7 January 2021
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The potential for gene therapy in pancreatic cancer
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Gene therapy for pancreatic and biliary malignancies
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Crossref
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7 January 2021
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Lentiviral vectors: turning a deadly foe into a therapeutic agent
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Crossref
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7 January 2021
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Suppression of angiogenesis by lentiviral delivery of PEX, a noncatalytic fragment of matrix metalloproteinase 2.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Gene transfer into stimulated and unstimulated T lymphocytes by HIV-1-derived lentiviral vectors.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Transduction of human CD34+ cells that mediate long-term engraftment of NOD/SCID mice by HIV vectors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Stable transduction of quiescent CD34(+)CD38(-) human hematopoietic cells by HIV-1-based lentiviral vectors
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Site-specific integration by adeno-associated virus
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Trans-splicing vectors expand the utility of adeno-associated virus for gene therapy
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increasing the size of rAAV-mediated expression cassettes in vivo by intermolecular joining of two complementary vectors
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Construction of recombinant adeno-associated virus vector containing the rat preproinsulin II gene
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Combined effects of adeno-associated virus vector and a herpes simplex virus mutant as neoplastic therapy
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
An adenovirus mutant that replicates selectively in p53-deficient human tumor cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effective gene therapy for pancreatic cancer by cytokines mediated by restricted replication-competent adenovirus
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Specific oncolytic activity of herpesvirus saimiri in pancreatic cancer cells.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
An adenovirus-Epstein-Barr virus hybrid vector that stably transforms cultured cells with high efficiency
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Stable in vivo gene transduction via a novel adenoviral/retroviral chimeric vector
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Direct immunologic activities of CpG DNA and implications for gene therapy
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cationic liposomes for direct gene transfer in therapy of cancer and other diseases.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Direct gene transfer into the rat pancreas using DNA-liposomes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Transferrin-polycation conjugates as carriers for DNA uptake into cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
A chimeric fusion protein containing transforming growth factor-alpha mediates gene transfer via binding to the EGF receptor
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein kinase B activation and lamellipodium formation are independent phosphoinositide 3-kinase-mediated events differentially regulated by endogenous Ras.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of pancreatic cancer by the dominant negative ras mutant, N116Y.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The dominant negative H-ras mutant, N116Y, suppresses growth of metastatic human pancreatic cancer cells in the liver of nude mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytotoxic CD4+ and CD8+ T lymphocytes, generated by mutant p21-ras (12Val) peptide vaccination of a patient, recognize 12Val-dependent nested epitopes present within the vaccine peptide and kill autologous tumour cells carrying this mutation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Characterisation of immune responses in pancreatic carcinoma patients after mutant p21 ras peptide vaccination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
KRAS codon 12 mutations occur very frequently in pancreatic adenocarcinomas
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ki-ras oncogene activation in preinvasive pancreatic cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antisense regulation of oncogenes in human cancer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of Ki-ras p21 levels leading to growth inhibition of pancreatic cancer cell lines with Ki-ras mutation but not those without Ki-ras mutation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ribozyme as an approach for growth suppression of human pancreatic cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Adenovirus-mediated anti-K-ras ribozyme induces apoptosis and growth suppression of human pancreatic carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The cancer-associated Sm-like oncogene: a novel target for the gene therapy of pancreatic cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of adenovirus-mediated p16INK4A expression on cell cycle arrest are determined by endogenous p16 and Rb status in human cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Abnormalities of the RB1 and DCC tumor suppressor genes: Uncommon in human pancreatic adenocarcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparison of the effectiveness of adenovirus vectors expressing cyclin kinase inhibitors p16INK4A, p18INK4C, p19INK4D, p21(WAF1/CIP1) and p27KIP1 in inducing cell cycle arrest, apoptosis and inhibition of tumorigenicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Adenovirus-mediated p16/CDKN2 gene transfer suppresses glioma invasion in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of pRb phosphorylation and cell cycle progression by an antennapedia-p16(INK4A) fusion peptide in pancreatic cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Adenovirus-mediated transfer of p53 and p16(INK4a) results in pancreatic cancer regression in vitro and in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Adenovirally transferred p16INK4/CDKN2 and p53 genes cooperate to induce apoptotic tumor cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic background determines the response to adenovirus-mediated wild-type p53 expression in pancreatic tumor cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p16INK4 expression is associated with the increased sensitivity of human non-small cell lung cancer cells to DNA topoisomerase I inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nucleolar Arf sequesters Mdm2 and activates p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tissue-specific alternative splicing in the human INK4a/ARF cell cycle regulatory locus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The ARF/p53 pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel cellular protein (MTBP) binds to MDM2 and induces a G1 arrest that is suppressed by MDM2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Assignment of the MDM2 binding protein gene (MTBP) to human chromosome band 8q24 by in situ hybridization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Abnormalities of the p53 tumour suppressor gene in human pancreatic cancer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Adenovirus-mediated wild-type p53 tumor suppressor gene therapy induces apoptosis and suppresses growth of human pancreatic cancer [seecomments]
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tp53 gene therapy: a key to modulating resistance to anticancer therapies?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alteration of drug chemosensitivity caused by the adenovirus-mediated transfer of the wild-type p53 gene in human lung cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modulation of drug cytotoxicity by reintroduction of wild-type p53 gene (Ad5CMV-p53) in human pancreatic cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-7404%2801%2900011-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0960-7404(01)00011-1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11476989
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11476989%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
Fatcat ID
release_yr4petuuirhrlekat3itmifnhq
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/yr4petuuirhrlekat3itmifnhq
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PubMed publication ID
11476989
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11476989
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11476989%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
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