(Q34324885)

1 August 2017

title

Metalloendoprotease cleavage triggers gelsolin amyloidogenesis (English)

1 reference

1 August 2017

7

Jeffery W Kelly

1 reference

1 August 2017

Lesley J Page

1

1 reference

1 August 2017

Ji Young Suk

2

1 reference

1 August 2017

Mary E Huff

3

1 reference

1 August 2017

Hee-Jong Lim

4

1 reference

1 August 2017

John Venable

5

1 reference

1 August 2017

John Yates

6

1 reference

1 August 2017

William E Balch

8

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1 August 2017

language of work or name

English

0 references

publication date

10 November 2005

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1 August 2017

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1 August 2017

volume

24

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1 August 2017

issue

23

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1 August 2017

page(s)

4124-4132

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The biological and chemical basis for tissue-selective amyloid disease

1 August 2017

cites work

1 reference

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6 July 2018

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6 July 2018

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6 July 2018

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Furin initiates gelsolin familial amyloidosis in the Golgi through a defect in Ca(2+) stabilization

6 July 2018

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6 July 2018

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6 July 2018

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Effects of the beta-amyloid and carboxyl-terminal fragment of Alzheimer's amyloid precursor protein on the production of the tumor necrosis factor-alpha and matrix metalloproteinase-9 by human monocytic THP-1.

6 July 2018

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6 July 2018

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Gelsolin, a multifunctional actin regulatory protein

6 July 2018

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Identification and characterization of human MT5-MMP, a new membrane-bound activator of progelatinase a overexpressed in brain tumors

6 July 2018

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6 July 2018

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Identification and characterization of the fifth membrane-type matrix metalloproteinase MT5-MMP.

6 July 2018

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Conformational changes and disease--serpins, prions and Alzheimer's.

6 July 2018

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6 July 2018

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Identification of soluble type of membrane-type matrix metalloproteinase-3 formed by alternatively spliced mRNA

6 July 2018

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6 July 2018

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The crystal structure of plasma gelsolin: implications for actin severing, capping, and nucleation

6 July 2018

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Membrane-type-2 matrix metalloproteinase can initiate the processing of progelatinase A and is regulated by the tissue inhibitors of metalloproteinases

6 July 2018

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6 July 2018

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The soluble catalytic domain of membrane type 1 matrix metalloproteinase cleaves the propeptide of progelatinase A and initiates autoproteolytic activation. Regulation by TIMP-2 and TIMP-3.

6 July 2018

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Mechanism of cell surface activation of 72-kDa type IV collagenase. Isolation of the activated form of the membrane metalloprotease

6 July 2018

1 reference

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Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin-binding domain

6 July 2018

1 reference

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Gelsolin: calcium- and polyphosphoinositide-regulated actin-modulating protein

6 July 2018

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Proteoglycans in the pathogenesis of Alzheimer's disease and other amyloidoses

6 July 2018

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Gelsolin variant (Asn-187) in familial amyloidosis, Finnish type

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1356312

Mutation in gelsolin gene in Finnish hereditary amyloidosis

6 July 2018

1 reference

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Amyloid in familial amyloidosis, Finnish type, is antigenically and structurally related to gelsolin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1356312

6 July 2018

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Heparin and other glycosaminoglycans stimulate the formation of amyloid fibrils from alpha-synuclein in vitro.

6 July 2018

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Protein folding and disease: a view from the first Horizon Symposium.

21 January 2018

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Pathogenic A beta induces the expression and activation of matrix metalloproteinase-2 in human cerebrovascular smooth muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600872

Functional consequences of amyloidosis mutation for gelsolin polypeptide -- analysis of gelsolin-actin interaction and gelsolin processing in gelsolin knock-out fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600872

Brain matrix metalloproteinase 1 levels are elevated in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600872

Unveiling the surface epitopes that render tissue inhibitor of metalloproteinase-1 inactive against membrane type 1-matrix metalloproteinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600872

Increased plasma levels of matrix metalloproteinase-9 in patients with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600872

Interaction between matrix metalloproteinase 3 and the epsilon4 allele of apolipoprotein E increases the risk of Alzheimer's disease in Finns

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600872

Characterization of a truncated recombinant form of human membrane type 3 matrix metalloproteinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600872

A sulfated proteoglycan aggregation factor mediates amyloid-beta peptide fibril formation and neurotoxicity.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1356312

Low molecular weight inhibitors in corneal ulceration

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1356312

Inhibition of angiogenesis by the matrix metalloprotease inhibitor N-[2R-2-(hydroxamidocarbonymethyl)-4-methylpentanoyl)]-L-tryptophan methylamide.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1356312

The amyloidogenicity of gelsolin is controlled by proteolysis and pH

28 October 2018

1 reference

12 December 2020

MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover

1 reference

12 December 2020

The in vitro activity of ADAM-10 is inhibited by TIMP-1 and TIMP-3

1 reference

12 December 2020

Muscle is the major source of plasma gelsolin

1 reference

12 December 2020

Finnish hereditary amyloidosis. Amino acid sequence homology between the amyloid fibril protein and human plasma gelsoline

1 reference

12 December 2020

Isolation and characterization of cardiac amyloid in familial amyloid polyneuropathy type IV (Finnish): relation of the amyloid protein to variant gelsolin

1 reference

12 December 2020

Demonstration of a circulating 65K gelsolin variant specific for familial amyloidosis, Finnish type

1 reference

12 December 2020

Toward understanding the pathogenic mechanisms in gelsolin-related amyloidosis: in vitro expression reveals an abnormal gelsolin fragment

1 reference

12 December 2020

In vitro expression analysis shows that the secretory form of gelsolin is the sole source of amyloid in gelsolin-related amyloidosis

1 reference

12 December 2020

Tissue distribution and levels of gelsolin mRNA in normal individuals and patients with gelsolin-related amyloidosis

1 reference

12 December 2020

Identification of the circulating amyloid precursor and other gelsolin metabolites in patients with G654A mutation in the gelsolin gene (Finnish familial amyloidosis): pathogenetic and diagnostic implications

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.EMBOJ.7600872

1 reference

1 August 2017

1 reference

1 August 2017

1 reference