(Q34328635)

1 August 2017

Oncogenic Ras promotes butyrate-induced apoptosis through inhibition of gelsolin expression (English)

1 reference

1 August 2017

Lidija Klampfer

1

1 reference

1 August 2017

Jie Huang

2

1 reference

1 August 2017

Takehiko Sasazuki

3

1 reference

1 August 2017

Senji Shirasawa

4

1 reference

1 August 2017

Leonard Augenlicht

5

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1 August 2017

language of work or name

English

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publication date

22 June 2004

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Journal of Biological Chemistry

1 August 2017

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1 August 2017

279

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1 August 2017

36680-36688

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1 August 2017

35

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Withdrawal of butyrate from the colonic mucosa triggers "mass apoptosis" primarily in the G0/G1 phase of the cell cycle

1 August 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Histone acetylation and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Sodium butyrate induces apoptosis in human colonic tumour cell lines in a p53-independent pathway: implications for the possible role of dietary fibre in the prevention of large-bowel cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Role of short-chain fatty acids in the prevention of colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Butyrate and the colonocyte. Implications for neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Lessons from hereditary colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Genetic pathways in colorectal and other cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Synergy between Apc min and an activated ras mutation is sufficient to induce colon carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Tumorigenic conversion of p53-deficient colon epithelial cells by an activated Ki-ras gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Mutations in APC, Kirsten-ras, and p53--alternative genetic pathways to colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Targeted expression of oncogenic K-ras in intestinal epithelium causes spontaneous tumorigenesis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

A genome-wide survey of RAS transformation targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Increasing complexity of the Ras signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Understanding Ras: 'it ain't over 'til it's over'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

The dark side of Ras: regulation of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Altered growth of human colon cancer cell lines disrupted at activated Ki-ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Functions of gelsolin: motility, signaling, apoptosis, cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Caspase-3-induced gelsolin fragmentation contributes to actin cytoskeletal collapse, nucleolysis, and apoptosis of vascular smooth muscle cells exposed to proinflammatory cytokines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Human gelsolin prevents apoptosis by inhibiting apoptotic mitochondrial changes via closing VDAC

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Gelsolin inhibits apoptosis by blocking mitochondrial membrane potential loss and cytochrome c release

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Cell motility as a prognostic factor in Stage I nonsmall cell lung carcinoma: the role of gelsolin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Induction of apoptosis by gelsolin truncates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Growth-inhibitory functions of a mutated gelsolin (His321) in NIH/3T3 mouse fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Gene expression profiling of colon cancer by DNA microarrays and correlation with histoclinical parameters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Reversion of v-H-ras-transformed NIH 3T3 cells by apigenin through inhibiting mitogen activated protein kinase and its downstream oncogenes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Transformation stimulates glucose transporter gene expression in the absence of protein kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Oncogenic Ki-ras inhibits the expression of interferon-responsive genes through inhibition of STAT1 and STAT2 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Adenovirus E1B-19K/BCL-2 interacting protein BNIP3 contains a BH3 domain and a mitochondrial targeting sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

A novel gene product that couples TCR signaling to Fas(CD95) expression in activation-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Molecular mechanism of transcriptional repression of gelsolin in human breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Tributyrin, an oral butyrate analogue, induces apoptosis through the activation of caspase-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Resistance to butyrate-induced cell differentiation and apoptosis during spontaneous Caco-2 cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

A mechanism of repression of TGFbeta/ Smad signaling by oncogenic Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Mutant K-ras enhances apoptosis in embryonic stem cells in combination with DNA damage and is associated with increased levels of p19(ARF).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Induction of apoptosis in fibroblasts by c-myc protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Cell proliferation and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Ras activation leads to cell proliferation or apoptotic cell death upon interleukin-2 stimulation or lymphokine deprivation, respectively

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Cooperative interaction between c-myc and bcl-2 proto-oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Suppression of Myc-induced apoptosis in beta cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Inhibition of apoptosis by the actin-regulatory protein gelsolin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

p21 Waf1/Cip1 can protect human colon carcinoma cells against p53-dependent and p53-independent apoptosis induced by natural chemopreventive and therapeutic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

Control of cytoplasmic actin gel–sol transformation by gelsolin, a calcium-dependent regulatory protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405197200

21 January 2018

Identifiers

DOI

10.1074/JBC.M405197200

1 reference

1 August 2017

1 reference