(Q34328772)

1 August 2017

title

Nicotinamide phosphoribosyl transferase (Nampt) is required for de novo lipogenesis in tumor cells (English)

1 reference

1 August 2017

1 reference

Ralph B. D'Agostino Sr.

series ordinal

3

object named as

Ralph B D'Agostino

1 reference

1 August 2017

Sarah C Bowlby

1

1 reference

1 August 2017

Michael J Thomas

series ordinal

2

1 reference

1 August 2017

Steven J Kridel

series ordinal

4

1 reference

1 August 2017

language of work or name

English

0 references

publication date

29 June 2012

1 reference

1 August 2017

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1 August 2017

volume

7

1 reference

1 August 2017

issue

6

1 reference

1 August 2017

page(s)

e40195

1 reference

Creative Commons Attribution 4.0 International

1 August 2017

copyright license

start time

29 June 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Overexpression of Nampt in gastric cancer and chemopotentiating effects of the Nampt inhibitor FK866 in combination with fluorouracil

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NAMPT overexpression in prostate cancer and its contribution to tumor cell survival and stress response

6 July 2018

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Inhibition of nicotinamide phosphoribosyltransferase: cellular bioenergetics reveals a mitochondrial insensitive NAD pool

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6 July 2018

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The small molecule GMX1778 is a potent inhibitor of NAD+ biosynthesis: strategy for enhanced therapy in nicotinic acid phosphoribosyltransferase 1-deficient tumors

6 July 2018

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A phosphorylation-acetylation switch regulates STAT1 signaling

6 July 2018

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Nampt: linking NAD biology, metabolism and cancer

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Anticancer agent CHS-828 inhibits cellular synthesis of NAD.

6 July 2018

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SIRT1 acts as a nutrient-sensitive growth suppressor and its loss is associated with increased AMPK and telomerase activity

6 July 2018

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Fatty acid synthase inhibitors: new directions for oncology

6 July 2018

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The pharmacokinetics, toxicities, and biologic effects of FK866, a nicotinamide adenine dinucleotide biosynthesis inhibitor

6 July 2018

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Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival

6 July 2018

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Quantitative analysis of phospholipids by thin-layer chromatography and phosphorus analysis of spots

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387004

Nicotine-induced activation of AMP-activated protein kinase inhibits fatty acid synthase in 3T3L1 adipocytes: a role for oxidant stress

6 July 2018

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Inhibition of fatty acid synthase induces endoplasmic reticulum stress in tumor cells.

6 July 2018

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6 July 2018

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Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387004

Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387004

Phase I study and pharmacokinetic of CHS-828, a guanidino-containing compound, administered orally as a single dose every 3 weeks in solid tumours: an ECSG/EORTC study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387004

The adaptor protein Tks5/Fish is required for podosome formation and function, and for the protease-driven invasion of cancer cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387004

The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387004

FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387004

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387004

Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387004

A Phase I study of CHS 828 in patients with solid tumor malignancy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387004

Cloning and characterization of the cDNA encoding a novel human pre-B-cell colony-enhancing factor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387004

Nicotinate phosphoribosyltransferase of yeast. Purification and properties

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387004

Identification by amino acid sequencing of three major regulatory phosphorylation sites on rat acetyl-CoA carboxylase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387004

Yeast acetyl-CoA carboxylase: in vitro phosphorylation by mammalian and yeast protein kinases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387004

PBEF1/NAmPRTase/Visfatin: a potential malignant astrocytoma/glioblastoma serum marker with prognostic value.

6 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040195

Nicotinamide phosphoribosyltransferase imparts human endothelial cells with extended replicative lifespan and enhanced angiogenic capacity in a high glucose environment

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040195

Orlistat is a novel inhibitor of fatty acid synthase with antitumor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040195

De novo lipogenesis protects cancer cells from free radicals and chemotherapeutics by promoting membrane lipid saturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040195

Metabolic signatures associated with a NAD synthesis inhibitor-induced tumor apoptosis identified by 1H-decoupled-31P magnetic resonance spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040195

Modulation of FoxO1 phosphorylation/acetylation by baicalin during aging.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387004

Enzymatic synthesis of nicotinamide mononucleotide.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387004

Molecular species composition of rat liver phospholipids by ESI-MS/MS: the effect of chromatography.

27 October 2018

1 reference

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Fatty acid synthase gene overexpression and copy number gain in prostate adenocarcinoma☆

27 October 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040195

SIRT1 markedly extends replicative lifespan if the NAD+ salvage pathway is enhanced

21 January 2018

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12 December 2020

Extension of human cell lifespan by nicotinamide phosphoribosyltransferase

1 reference

12 December 2020

Pharmacological inhibitors of mammalian fatty acid synthase suppress DNA replication and induce apoptosis in tumor cell lines

1 reference

12 December 2020

Chemical proteomics identifies Nampt as the target of CB30865, an orphan cytotoxic compound

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0040195

Identifiers

DOI

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/rtimwsixvrevjonrglr57mar3a

30 July 2022

release_rtimwsixvrevjonrglr57mar3a

ADS bibcode

2012PLoSO...740195B

0 references

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/rtimwsixvrevjonrglr57mar3a

30 July 2022

https://api.fatcat.wiki/v0/release/rtimwsixvrevjonrglr57mar3a

1 reference

30 July 2022

https://api.fatcat.wiki/v0/release/rtimwsixvrevjonrglr57mar3a

1 reference

30 July 2022