(Q34343530)

1 August 2017

title

Emerging artemisinin resistance in the border areas of Thailand (English)

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1 August 2017

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2

Juntra Karbwang

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1 August 2017

1

Kesara Na-Bangchang

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1 August 2017

language of work or name

English

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publication date

1 May 2013

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Expert Review of Clinical Pharmacology

1 August 2017

published in

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1 August 2017

volume

6

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1 August 2017

issue

3

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1 August 2017

page(s)

307-322

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Current status of malaria chemotherapy and the role of pharmacology in antimalarial drug research and development

1 August 2017

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21 January 2018

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Two fixed-dose artemisinin combinations for drug-resistant falciparum and vivax malaria in Papua, Indonesia: an open-label randomised comparison

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21 January 2018

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Chloroquine-resistant falciparum malaria in Thailand

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Compliance with a three-day course of artesunate-mefloquine combination and baseline anti-malarial treatment in an area of Thailand with highly multidrug resistant falciparum malaria

21 January 2018

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Early results of integrated malaria control and implications for the management of fever in under-five children at a peripheral health facility: a case study of Chongwe rural health centre in Zambia

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Efficacy of artemether-lumefantrine for the treatment of uncomplicated falciparum malaria in northwest Cambodia

21 January 2018

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21 January 2018

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In vivo sensitivity monitoring of mefloquine monotherapy and artesunate-mefloquine combinations for the treatment of uncomplicated falciparum malaria in Thailand in 2003.

21 January 2018

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Declining artesunate-mefloquine efficacy against falciparum malaria on the Cambodia-Thailand border

21 January 2018

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Evidence of Artemisinin-Resistant Malaria in Western Cambodia

21 January 2018

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Artemisinin-resistant malaria in Asia.

21 January 2018

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21 January 2018

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Artemisinin resistance in Cambodia: a clinical trial designed to address an emerging problem in Southeast Asia

21 January 2018

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Declining in efficacy of a three-day combination regimen of mefloquine-artesunate in a multi-drug resistance area along the Thai-Myanmar border

21 January 2018

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Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study

21 January 2018

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Discovery, mechanisms of action and combination therapy of artemisinin

21 January 2018

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Plasmodium sensitivity to artemisinins: magic bullets hit elusive targets

21 January 2018

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Pharmacokinetics of oral artesunate in thai patients with uncomplicated falciparum malaria

21 January 2018

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High heritability of malaria parasite clearance rate indicates a genetic basis for artemisinin resistance in western Cambodia

21 January 2018

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The threat of artemisinin-resistant malaria

21 January 2018

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Intrahost modeling of artemisinin resistance in Plasmodium falciparum

21 January 2018

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Ex vivo drug sensitivity profiles of Plasmodium falciparum field isolates from Cambodia and Thailand, 2005 to 2010, determined by a histidine-rich protein-2 assay

21 January 2018

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21 January 2018

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Sensitivity to artemisinin, mefloquine and quinine of Plasmodium falciparum in northwestern Thailand

21 January 2018

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Reduced in vitro susceptibility to artemisinin derivatives associated with multi-resistance in a traveller returning from South-East Asia

21 January 2018

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Changes in susceptibility of Plasmodium falciparum to artesunate in vitro in Yunnan Province, China

21 January 2018

1 reference

Resistance of Plasmodium falciparum to antimalarial drugs in a highly endemic area of southern Viet Nam: a study in vivo and in vitro

21 January 2018

1 reference

Resistance of Plasmodium falciparum field isolates to in-vitro artemether and point mutations of the SERCA-type PfATPase6.

21 January 2018

1 reference

Artemisinin-resistant malaria: research challenges, opportunities, and public health implications

21 January 2018

1 reference

Declining responsiveness of Plasmodium falciparum infections to artemisinin-based combination treatments on the Kenyan coast

21 January 2018

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A call to action: addressing the challenge of artemisinin-resistant malaria

21 January 2018

1 reference

Pharmacokinetics and pharmacodynamics of lumefantrine (benflumetol) in acute falciparum malaria

21 January 2018

1 reference

Molecular and pharmacological determinants of the therapeutic response to artemether-lumefantrine in multidrug-resistant Plasmodium falciparum malaria

21 January 2018

1 reference

The dynamics of drug resistance in Plasmodium falciparum

21 January 2018

1 reference

Monitoring of in vitro susceptibilities and molecular markers of resistance of Plasmodium falciparum isolates from Thai-Myanmar border to chloroquine, quinine, mefloquine and artesunate

21 January 2018

1 reference

Artemether/lumefantrine in the treatment of uncomplicated falciparum malaria

21 January 2018

1 reference

Population pharmacokinetics and therapeutic response of CGP 56697 (artemether + benflumetol) in malaria patients

21 January 2018

1 reference

Distribution of hemoglobin E and beta-thalassemia in Kampuchea (Cambodia).

21 January 2018

1 reference

Artemisinin-resistant Plasmodium falciparum in Pursat province, western Cambodia: a parasite clearance rate study

21 January 2018

1 reference

Decreased sensitivity of artesunate and chloroquine of Plasmodium falciparum infecting hemoglobin H and/or hemoglobin constant spring erythrocytes.

21 January 2018

1 reference

Resistance to artemisinin of malaria parasites (Plasmodium falciparum) infecting alpha-thalassemic erythrocytes in vitro. Competition in drug accumulation with uninfected erythrocytes.

21 January 2018

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Inactivation of artemisinin by thalassemic erythrocytes.

21 January 2018

1 reference

Impaired antioxidant defense in hemoglobin E-containing erythrocytes: a mechanism protective against malaria?

21 January 2018

1 reference

Antioxidant deficit and enhanced susceptibility to oxidative damage in individuals with different forms of alpha-thalassaemia

21 January 2018

1 reference

Glucose-6-phosphate dehydrogenase variants associated with favism in Thai children.

21 January 2018

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The molecular mechanism of action of artemisinin--the debate continues.

21 January 2018

1 reference

The mechanisms of parasite clearance after antimalarial treatment of Plasmodium falciparum malaria

21 January 2018

1 reference

Central role of the spleen in malaria parasite clearance

21 January 2018

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Ex vivo perfusion of human spleens maintains clearing and processing functions

21 January 2018

1 reference

Pharmacogenetics of antimalarial drugs: effect on metabolism and transport

21 January 2018

1 reference

Identification of human cytochrome P(450)s that metabolise anti-parasitic drugs and predictions of in vivo drug hepatic clearance from in vitro data

21 January 2018

1 reference

Structure, function, regulation and polymorphism of human cytochrome P450 2A6.

21 January 2018

1 reference

CYP2A6 genotypes and coumarin-oxidation phenotypes in a Thai population and their relationship to tobacco smoking

21 January 2018

1 reference

High prevalence of cytochrome P450 2A6*1A alleles in a black African population of Ghana

21 January 2018

1 reference

Artemisinin: mechanisms of action, resistance and toxicity

21 January 2018

1 reference

Know your enemy: understanding the role of PfCRT in drug resistance could lead to new antimalarial tactics

21 January 2018

1 reference

Artemisinin activity against Plasmodium falciparum requires hemoglobin uptake and digestion

21 January 2018

1 reference

Artemisinins and the biological basis for the PfATP6/SERCA hypothesis

21 January 2018

1 reference

Disruption of a Plasmodium falciparum Multidrug Resistance-associated Protein (PfMRP) Alters Its Fitness and Transport of Antimalarial Drugs and Glutathione

21 January 2018

1 reference

Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum

21 January 2018

1 reference

Increased sensitivity to the antimalarials mefloquine and artemisinin is conferred by mutations in the pfmdr1 gene of Plasmodium falciparum

21 January 2018

1 reference

Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum

21 January 2018

1 reference

pfmdr1 mutations contribute to quinine resistance and enhance mefloquine and artemisinin sensitivity in Plasmodium falciparum

21 January 2018

1 reference

Selection for mefloquine resistance in Plasmodium falciparum is linked to amplification of the pfmdr1 gene and cross-resistance to halofantrine and quinine

21 January 2018

1 reference

Resistance to antimalarials in Southeast Asia and genetic polymorphisms in pfmdr1.

21 January 2018

1 reference

Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number

21 January 2018

1 reference

Decreasing pfmdr1 copy number in plasmodium falciparum malaria heightens susceptibility to mefloquine, lumefantrine, halofantrine, quinine, and artemisinin

21 January 2018

1 reference

Safety of epoietin beta-quinine drug combination in children with cerebral malaria in Mali

21 January 2018

1 reference

Polymorphisms of molecular markers of antimalarial drug resistance and relationship with artesunate-mefloquine combination therapy in patients with uncomplicated Plasmodium falciparum malaria in Thailand.

21 January 2018

1 reference

Pfmdr1 copy number and arteminisin derivatives combination therapy failure in falciparum malaria in Cambodia

21 January 2018

1 reference

Increased pfmdr1 copy number and sequence polymorphisms in Plasmodium falciparum isolates from Sudanese malaria patients treated with artemether-lumefantrine

21 January 2018

1 reference

Novel polymorphisms in Plasmodium falciparum ABC transporter genes are associated with major ACT antimalarial drug resistance

21 January 2018

1 reference

A single amino acid residue can determine the sensitivity of SERCAs to artemisinins

21 January 2018

1 reference

Molecular monitoring of Plasmodium falciparum resistance to artemisinin in Tanzania

21 January 2018

1 reference

Diversity of the sarco/endoplasmic reticulum Ca(2+)-ATPase orthologue of Plasmodium falciparum (PfATP6).

21 January 2018

1 reference

Plasmodium falciparum from Pará state (Brazil) shows satisfactory in vitro response to artemisinin derivatives and absence of the S769N mutation in the SERCA-type PfATPase6.

21 January 2018

1 reference

Detection of novel point mutations in the Plasmodium falciparum ATPase6 candidate gene for resistance to artemisinins

21 January 2018

1 reference

Role of pfmdr1 amplification and expression in induction of resistance to artemisinin derivatives in Plasmodium falciparum

21 January 2018

1 reference

Exploring the contribution of candidate genes to artemisinin resistance in Plasmodium falciparum

21 January 2018

1 reference

Geographic structuring of the Plasmodium falciparum sarco(endo)plasmic reticulum Ca2+ ATPase (PfSERCA) gene diversity

21 January 2018

1 reference

Investigations into the role of the Plasmodium falciparum SERCA (PfATP6) L263E mutation in artemisinin action and resistance

21 January 2018

1 reference

Molecular analysis of pfatp6 and pfmdr1 polymorphisms and their association with in vitro sensitivity in Plasmodium falciparum isolates from the Thai-Myanmar border.

21 January 2018

1 reference

Gene encoding a deubiquitinating enzyme is mutated in artesunate- and chloroquine-resistant rodent malaria parasites

21 January 2018

1 reference

Experimental evolution, genetic analysis and genome re-sequencing reveal the mutation conferring artemisinin resistance in an isogenic lineage of malaria parasites

21 January 2018

1 reference

Artemisinin‐induced dormancy in plasmodium falciparum: duration, recovery rates, and implications in treatment failure

21 January 2018

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Increased tolerance to artemisinin in Plasmodium falciparum is mediated by a quiescence mechanism

21 January 2018

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Artemisinin resistance in Plasmodium falciparum is associated with an altered temporal pattern of transcription

21 January 2018

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In vivo parasitological measures of artemisinin susceptibility

21 January 2018

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Decreased in vitro susceptibility of Plasmodium falciparum isolates to artesunate, mefloquine, chloroquine, and quinine in Cambodia from 2001 to 2007

21 January 2018

1 reference

Efficacy of artesunate plus amodiaquine versus that of artemether-lumefantrine for the treatment of uncomplicated childhood Plasmodium falciparum malaria in Zanzibar, Tanzania

21 January 2018

1 reference

In vivo selection of Plasmodium falciparum pfmdr1 86N coding alleles by artemether-lumefantrine (Coartem).

21 January 2018

1 reference

The role of pfmdr1 in Plasmodium falciparum tolerance to artemether-lumefantrine in Africa

21 January 2018

1 reference

Failure of artesunate-mefloquine combination therapy for uncomplicated Plasmodium falciparum malaria in southern Cambodia

21 January 2018

1 reference

Molecular surveillance for multidrug-resistant Plasmodium falciparum, Cambodia

21 January 2018

1 reference

Are we losing artemisinin combination therapy already?

21 January 2018

1 reference

Geographical distribution of selected and putatively neutral SNPs in Southeast Asian malaria parasites

21 January 2018

1 reference

Plasmodium falciparum genome-wide scans for positive selection, recombination hot spots and resistance to antimalarial drugs

21 January 2018

1 reference

Treatment of Plasmodium falciparum malaria with pyrimethamine-sulfadoxine: selective pressure for resistance is a function of long elimination half-life

21 January 2018

1 reference

A randomized trial of artemether-lumefantrine versus mefloquine-artesunate for the treatment of uncomplicated multi-drug resistant Plasmodium falciparum on the western border of Thailand

21 January 2018

1 reference

Monitoring antimalarial drug efficacy: current challenges

21 January 2018

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Access to artemisinin combination therapy for malaria in remote areas of Cambodia

21 January 2018

1 reference

Variations in frequencies of drug resistance in Plasmodium falciparum

21 January 2018

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The last man standing is the most resistant: eliminating artemisinin-resistant malaria in Cambodia

21 January 2018

1 reference

Probability of emergence of antimalarial resistance in different stages of the parasite life cycle.

21 January 2018

1 reference

Mass administrations of antimalarial drugs

21 January 2018

1 reference

Monitoring antimalarial resistance: launching a cooperative effort

21 January 2018

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Genome wide adaptations of Plasmodium falciparum in response to lumefantrine selective drug pressure

21 January 2018

1 reference

Pharmacologic advances in the global control and treatment of malaria: combination therapy and resistance

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1586/ECP.13.17

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1 August 2017

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