(Q34346292)

1 August 2017

title

The role of CYP2D6 in primary and secondary oxidative metabolism of dextromethorphan: in vitro studies using human liver microsomes (English)

1 reference

1 August 2017

G Mikus

4

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author name string

N L Kerry

series ordinal

1

1 reference

1 August 2017

A A Somogyi

series ordinal

2

1 reference

1 August 2017

F Bochner

series ordinal

3

1 reference

1 August 2017

language of work or name

English

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publication date

1 September 1994

1 reference

British Journal of Clinical Pharmacology

1 August 2017

published in

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1 August 2017

volume

38

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1 August 2017

issue

3

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1 August 2017

page(s)

243-248

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THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. II. SOLUBILIZATION, PURIFICATION, AND PROPERTIES

1 August 2017

cites work

1 reference

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Inhibition of human cytochrome P450 2D6 (CYP2D6) by methadone

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6 July 2018

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Impaired oxidation of debrisoquine in patients with perhexiline neuropathy

6 July 2018

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Pharmacogenetics of dextromethorphan O-demethylation in man.

6 July 2018

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Polymorphism of dextromethorphan oxidation in a French population

6 July 2018

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6 July 2018

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Anti-liver kidney microsome antibody recognizes a cytochrome P450 from the IID subfamily

6 July 2018

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Effect of quinidine on the dextromethorphan O-demethylase activity of microsomal fractions from human liver

6 July 2018

1 reference

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Phenotypic differences in dextromethorphan metabolism

6 July 2018

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Codeine O-demethylation co-segregates with polymorphic debrisoquine hydroxylation

6 July 2018

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In vitro inhibition of a polymorphic human liver P-450 isozyme by narcotic analgesics.

6 July 2018

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Simultaneous determination of dextromethorphan and three metabolites in plasma and urine using high-performance liquid chromatography with application to their disposition in man.

6 July 2018

1 reference

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Stereoselective inhibition of nortriptyline hydroxylation in man by quinidine

6 July 2018

1 reference

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Inhibition of debrisoquin clearance in perfused rat livers and inhibition of dextromethorphan metabolism in human liver microsomes by 4-hydroxydebrisoquin or other metabolites of debrisoquin

6 July 2018

1 reference

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Primary and secondary oxidative metabolism of dextromethorphan

6 July 2018

1 reference

Crossref

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Codeine o-demethylation: Rat strain differences and the effects of inhibitors

21 January 2018

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CYP2D6- and CYP3A-dependent metabolism of dextromethorphan in humans

21 January 2018

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21 January 2018

12 December 2020

Human hepatic cytochrome P450 2D6-like activity in nonhuman primates: catalytic characterization in vitro

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Inhibitory studies of mexiletine and dextromethorphan oxidation in human liver microsomes

27 October 2018

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12 December 2020

d-Propoxyphene is a potent inhibitor of debrisoquine, but not S-mephenytoin 4-hydroxylation in vivo

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12 December 2020

The antipsychotic clozapine is metabolized by the polymorphic human microsomal and recombinant cytochrome P450 2D6

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12 December 2020

Identification and characterization of the cytochrome P450 enzymes involved in N-dealkylation of propafenone: molecular base for interaction potential and variable disposition of active metabolites

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12 December 2020

Polymorphic dextromethorphan metabolism: co-segregation of oxidative O-demethylation with debrisoquin hydroxylation

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12 December 2020

High-performance liquid chromatographic assays for bufuralol 1'-hydroxylase, debrisoquine 4-hydroxylase, and dextromethorphan O-demethylase in microsomes and purified cytochrome P-450 isozymes of human liver

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12 December 2020

Bioactivation of the narcotic drug codeine in human liver is mediated by the polymorphic monooxygenase catalyzing debrisoquine 4-hydroxylation (cytochrome P-450 dbl/bufI)

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12 December 2020

Polymorphic O-demethylation of codeine

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12 December 2020

Dextromethorphan O-demethylation in liver microsomes as a prototype reaction to monitor cytochrome P-450 db1 activity

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12 December 2020

10.1111/J.1365-2125.1994.TB04348.X

Identifiers

DOI

1 reference

release_a23qpkhiancgldmdqja67y3o6q

1 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/a23qpkhiancgldmdqja67y3o6q

24 November 2022

mapped directly with Wikidata item

PMC publication ID

1364796

1 reference

1 August 2017

1 reference