(Q34357243)

1 August 2017

Bioactivation of dapsone to a cytotoxic metabolite: in vitro use of a novel two compartment system which contains human tissues (English)

1 reference

1 August 2017

0 references

1 reference

R J Riley

1

1 reference

1 August 2017

P Roberts

2

1 reference

1 August 2017

M D Coleman

3

1 reference

1 August 2017

N R Kitteringham

4

1 reference

1 August 2017

B K Park

5

1 reference

1 August 2017

language of work or name

English

0 references

publication date

1 September 1990

1 reference

British Journal of Clinical Pharmacology

1 August 2017

1 reference

1 August 2017

30

1 reference

1 August 2017

3

1 reference

1 August 2017

417-426

1 reference

Protein measurement with the Folin phenol reagent

1 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368145

THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. I. EVIDENCE FOR ITS HEMOPROTEIN NATURE

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368145

Alkylation of intracellular and extracellular DNA by dimethylnitrosamine following activation by isolated rat hepatocytes.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368145

In vitro assessment of pharmacogenetic susceptibility to toxic drug metabolites in humans.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368145

The polymorphic acetylation of dapsone in man

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368145

Studies of the metabolism of dapsone in man and experimental animals: formation of N-hydroxy metabolites

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368145

N-hydroxylation of 4,4'-diaminodiphenylsulphone (Dapsone) by liver microsomes, and in dogs and humans

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368145

In vitro evaluation of a toxic metabolite of sulfadiazine.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368145

Formation of glutathione conjugates by reactive metabolites of vinylidene chloride in microsomes and isolated hepatocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368145

Enzymatic activation of chemicals to toxic metabolites.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368145

The metabolism of 17 alpha-ethinyloestradiol by human liver microsomes: formation of catechol and chemically reactive metabolites

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368145

Role of dapsone hydroxylamine in dapsone-induced hemolytic anemia.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368145

Activation mechanisms to chemical toxicity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368145

In vitro and in vivo interactions of cells with biomaterials

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368145

A comparative study of the formation of chemically reactive drug metabolites by human liver microsomes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368145

An in vitro study of the microsomal metabolism and cellular toxicity of phenytoin, sorbinil and mianserin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368145

Bioactivation of dapsone to a cytotoxic metabolite by human hepatic microsomal enzymes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368145

Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368145

Toxic agents resulting from the oxidative metabolism of steroid hormones and drugs.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368145

Oxidative damage to neutrophils in glutathione synthetase deficiency

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368145

Inactivation of electrophilic metabolites by glutathione S-transferases and limitation of the system due to subcellular localization

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368145

A method for measurement of free and bound plasma cyst(e)ine

6 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1990.TB03793.X

Revised methods for the Salmonella mutagenicity test

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1990.TB03793.X

Acetaminophen toxicity in human lymphocytes in vitro.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368145

Metabolism of dapsone to a hydroxylamine by human neutrophils and mononuclear cells

27 October 2018

1 reference

12 December 2020

Agranulocytosis Due to Dapsone

1 reference

12 December 2020

Tissue culture cytotoxicity assay for cyclophosphamide metabolites in rat body fluids

1 reference

12 December 2020

In vitro inhibition of granulopoiesis by 4-amino-4'-hydroxylaminodiphenyl sulfone

1 reference

12 December 2020

Metabolic activation and cytotoxicity of cyclophosphamide in primary cultures of postnatal rat hepatocytes

1 reference

12 December 2020

Diffusion of reactive metabolites out of hepatocytes: studies with bromobenzene

1 reference

12 December 2020

Intra- and extra-cellular formation of metabolites from chemically reactive species

1 reference

12 December 2020

Detection and half-life of bromobenzene-3,4-oxide in blood

1 reference

12 December 2020

Separation of lymphocytes, granulocytes, and monocytes from human blood using iodinated density gradient media

1 reference

12 December 2020

A comparison of two cytotoxicity assays for the detection of metabolism-mediated toxicity in vitro: a study with cyclophosphamide

1 reference

12 December 2020

Differences in metabolism of sulfonamides predisposing to idiosyncratic toxicity

1 reference

12 December 2020

Metabolic basis of adverse drug reactions

1 reference

12 December 2020

Efflux of naphthalene oxide and reactive naphthalene metabolites from isolated hepatocytes

1 reference

12 December 2020

10.1111/J.1365-2125.1990.TB03793.X

Identifiers

DOI

1 reference

1 August 2017

1 reference

1 August 2017

1 reference