(Q34359270)

English

Identification of the substrate recognition and transport pathway in a eukaryotic member of the nucleobase-ascorbate transporter (NAT) family

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scholarly article

1 reference

Europe PubMed Central

1 August 2017

Identification of the substrate recognition and transport pathway in a eukaryotic member of the nucleobase-ascorbate transporter (NAT) family (English)

1 reference

Europe PubMed Central

1 August 2017

High-capacity, high-affinity uric acid-xanthine permease

0 references

Vassilios Myrianthopoulos

object named as

Vassilios Myrianthopoulos

3

0 references

George Diallinas

object named as

George Diallinas

4

0 references

Emmanuel Mikros

object named as

Emmanuel Mikros

5

0 references

1

object named as

Vasiliki Kosti

1 reference

Europe PubMed Central

1 August 2017

George Lambrinidis

2

object named as

George Lambrinidis

1 reference

Europe PubMed Central

1 August 2017

language of work or name

0 references

publication date

25 July 2012

1 reference

Europe PubMed Central

1 August 2017

1 reference

Europe PubMed Central

1 August 2017

7

1 reference

Europe PubMed Central

1 August 2017

7

1 reference

Europe PubMed Central

1 August 2017

e41939

1 reference

Europe PubMed Central

1 August 2017

copyright license

Creative Commons Attribution 4.0 International

25 July 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

The role of transmembrane segment TM3 in the xanthine permease XanQ of Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405029

6 July 2018

Opening the periplasmic cavity in lactose permease is the limiting step for sugar binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405029

6 July 2018

Structure-based discovery of prescription drugs that interact with the norepinephrine transporter, NET.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405029

6 July 2018

Substrate-modulated gating dynamics in a Na+-coupled neurotransmitter transporter homologue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405029

6 July 2018

Structure and mechanism of the uracil transporter UraA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405029

6 July 2018

The alternating access transport mechanism in LacY.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405029

6 July 2018

Structural basis of Na(+)-independent and cooperative substrate/product antiport in CaiT

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405029

6 July 2018

Cysteine-scanning analysis of helices TM8, TM9a, and TM9b and intervening loops in the YgfO xanthine permease: a carboxyl group is essential at ASP-276.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405029

6 July 2018

Substrate and drug binding sites in LeuT.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405029

6 July 2018

Single-molecule dynamics of gating in a neurotransmitter transporter homologue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405029

6 July 2018

Purine substrate recognition by the nucleobase-ascorbate transporter signature motif in the YgfO xanthine permease: ASN-325 binds and ALA-323 senses substrate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405029

6 July 2018

Transporters, channels, or simple diffusion? Dogmas, atypical roles and complexity in transport systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405029

6 July 2018

Role of intramembrane polar residues in the YgfO xanthine permease: HIS-31 and ASN-93 are crucial for affinity and specificity, and ASP-304 and GLU-272 are irreplaceable

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405029

6 July 2018

Structure-function relationships in the nucleobase-ascorbate transporter (NAT) family: lessons from model microbial genetic systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405029

6 July 2018

The nucleobase-ascorbate transporter (NAT) family: genomics, evolution, structure-function relationships and physiological role.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405029

6 July 2018

Novel procedure for modeling ligand/receptor induced fit effects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405029

6 July 2018

Docking studies show that D-glucose and quercetin slide through the transporter GLUT1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405029

6 July 2018

The nucleobase-ascorbate transporter (NAT) signature motif in UapA defines the function of the purine translocation pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405029

6 July 2018

Xanthine, xanthosine and its nucleotides: solution structures of neutral and ionic forms, and relevance to substrate properties in various enzyme systems and metabolic pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405029

6 July 2018

Ascorbic-acid transporter Slc23a1 is essential for vitamin C transport into the brain and for perinatal survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405029

6 July 2018

Chimeric purine transporters of Aspergillus nidulans define a domain critical for function and specificity conserved in bacterial, plant and metazoan homologues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405029

6 July 2018

Leaf permease1 gene of maize is required for chloroplast development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405029

6 July 2018

Comparative protein modelling by satisfaction of spatial restraints

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405029

6 July 2018

Sequence and regulation of the uapA gene encoding a uric acid-xanthine permease in the fungus Aspergillus nidulans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405029

6 July 2018

A gene coding for the uric acid-xanthine permease of Aspergillus nidulans: inactivational cloning, characterization, and sequence of a cis-acting mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405029

6 July 2018

Hydrogen bonds involving sulfur atoms in proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405029

6 July 2018

Comparative substrate recognition by bacterial and fungal purine transporters of the NAT/NCS2 family.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0041939

21 January 2018

Specific interdomain synergy in the UapA transporter determines its unique specificity for uric acid among NAT carriers

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0041939

21 January 2018

Dynamic elements at both cytoplasmically and extracellularly facing sides of the UapA transporter selectively control the accessibility of substrates to their translocation pathway

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0041939

21 January 2018

Substitution F569S converts UapA, a specific uric acid-xanthine transporter, into a broad specificity transporter for purine-related solutes.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0041939

21 January 2018

A novel-type substrate-selectivity filter and ER-exit determinants in the UapA purine transporter

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0041939

21 January 2018

Cysteine-scanning analysis of putative helix XII in the YgfO xanthine permease: ILE-432 and ASN-430 are important

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0041939

21 January 2018

A substrate translocation trajectory in a cytoplasm-facing topological model of the monocarboxylate/H⁺ symporter Jen1p

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0041939

21 January 2018

The mechanism of a neurotransmitter:sodium symporter--inward release of Na+ and substrate is triggered by substrate in a second binding site

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0041939

21 January 2018

Molecular mechanism of substrate specificity in the bacterial neutral amino acid transporter LeuT.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0041939

21 January 2018

An extended study of dimeric phenyl tropanes.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0041939

21 January 2018

Reassessment of models of facilitated transport and cotransport

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0041939

21 January 2018

A novel improved method for Aspergillus nidulans transformation.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0041939

21 January 2018

Mutational Analysis and Modeling Reveal Functionally Critical Residues in Transmembrane Segments 1 and 3 of the UapA Transporter

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0041939

21 January 2018

The first transmembrane segment (TMS1) of UapA contains determinants necessary for expression in the plasma membrane and purine transport

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0041939

21 January 2018

Initiator constitutive mutation with an ‘up-promoter’ effect in Aspergillus nidulans

2 references

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0041939

21 January 2018

https://pubmed.ncbi.nlm.nih.gov/22848666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amino acid residues N450 and Q449 are critical for the uptake capacity and specificity of UapA, a prototype of a nucleobase-ascorbate transporter family

1 reference

https://pubmed.ncbi.nlm.nih.gov/22848666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemistry. An almost-complete movie

1 reference

https://pubmed.ncbi.nlm.nih.gov/22848666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stabilizing the heterologously expressed uric acid-xanthine transporter UapA from the lower eukaryote Aspergillus nidulans

1 reference

https://pubmed.ncbi.nlm.nih.gov/22848666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0041939

1 reference

Europe PubMed Central

1 August 2017

2012PLoSO...741939K

0 references

1 reference

Europe PubMed Central

1 August 2017

1 reference

Europe PubMed Central

1 August 2017

ResearchGate publication ID

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