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Phosphoinositide 3-kinases in the gut: a link between inflammation and cancer?
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stated in
Europe PubMed Central
PubMed ID
11597520
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11597520%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
review article
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Europe PubMed Central
title
Phosphoinositide 3-kinases in the gut: a link between inflammation and cancer?
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
11597520
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11597520%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
author
Stephen G Ward
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
11597520
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11597520%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
author name string
S A Weaver
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
11597520
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11597520%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
publication date
1 October 2001
1 reference
stated in
Europe PubMed Central
PubMed ID
11597520
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11597520%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
published in
Trends in Molecular Medicine
1 reference
stated in
Europe PubMed Central
PubMed ID
11597520
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11597520%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
volume
7
1 reference
stated in
Europe PubMed Central
PubMed ID
11597520
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11597520%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
issue
10
1 reference
stated in
Europe PubMed Central
PubMed ID
11597520
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11597520%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
page(s)
455-462
1 reference
stated in
Europe PubMed Central
PubMed ID
11597520
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11597520%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
cites work
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7 January 2021
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7 January 2021
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IGF-I stimulates intestinal muscle cell growth by activating distinct PI 3-kinase and MAP kinase pathways
1 reference
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Crossref
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7 January 2021
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Phosphatidylinositol 3-kinases regulate ERK and p38 MAP kinases in canine colonic smooth muscle
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Role of PI3-kinase in the development of interstitial cells and pacemaking in murine gastrointestinal smooth muscle.
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The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
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7 January 2021
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Inherited mutations in PTEN that are associated with breast cancer, cowden disease, and juvenile polyposis
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Crossref
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7 January 2021
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Crossref
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7 January 2021
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Pten is essential for embryonic development and tumour suppression
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Crossref
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7 January 2021
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Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems
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Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells
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Crossref
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7 January 2021
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Increased levels of phosphatidylinositol 3-kinase activity in colorectal tumors.
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7 January 2021
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A specific function for phosphatidylinositol 3-kinase alpha (p85alpha-p110alpha) in cell survival and for phosphatidylinositol 3-kinase beta (p85alpha-p110beta) in de novo DNA synthesis of human colon carcinoma cells
1 reference
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7 January 2021
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Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration
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Crossref
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7 January 2021
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Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kgamma
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Crossref
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7 January 2021
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Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation.
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Crossref
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7 January 2021
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Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction
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Crossref
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7 January 2021
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Cytokine-induced apoptosis in epithelial HT-29 cells is independent of nitric oxide formation. Evidence for an interleukin-13-driven phosphatidylinositol 3-kinase-dependent survival mechanism
1 reference
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Crossref
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7 January 2021
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Downregulation of the pro-apoptotic protein Bak is required for the ras-induced transformation of intestinal epithelial cells.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902107-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of phosphatidylinositol 3-kinase is sufficient for cell cycle entry and promotes cellular changes characteristic of oncogenic transformation
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902107-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of the Phosphoinositide 3-Kinase Pathway Induces a Senescence-like Arrest Mediated by p27Kip1
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Crossref
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7 January 2021
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Increased AKT activity contributes to prostate cancer progression by dramatically accelerating prostate tumor growth and diminishing p27Kip1 expression
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902107-4
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7 January 2021
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NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase
1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902107-4
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Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Specific NF-kappaB blockade selectively inhibits tumour necrosis factor-alpha-induced COX-2 but not constitutive COX-1 gene expression in HT-29 cells
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Crossref
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7 January 2021
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Regulatory role of phosphatidylinositol 3-kinase on TNF-alpha-induced cyclooxygenase 2 expression in colonic epithelial cells.
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of constitutive cyclooxygenase-2 expression in colon carcinoma cells
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
The role of cyclooxygenase 2 in ulcerative colitis-associated neoplasia
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902107-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Increased neutrophil receptors for and response to the proinflammatory bacterial peptide formyl-methionyl-leucyl-phenylalanine in Crohn's disease.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902107-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902107-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Roles of phosphatidylinositol 3-kinase and Rac in the nuclear signaling by tumor necrosis factor-alpha in rat-2 fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902107-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel pathway for tumor necrosis factor-alpha and ceramide signaling involving sequential activation of tyrosine kinase, p21(ras), and phosphatidylinositol 3-kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902107-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor necrosis factor induces phosphorylation and translocation of BAD through a phosphatidylinositide-3-OH kinase-dependent pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902107-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nitric oxide synthase activity in ulcerative colitis and Crohn's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902107-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased interleukin 8 expression in the colon mucosa of patients with inflammatory bowel disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902107-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytokine messenger RNA profiles in inflammatory bowel disease mucosa detected by polymerase chain reaction amplification
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902107-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of NF-kappaB binding in HT-29 colon cancer cells by inhibition of phosphatidylinositol 3-kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902107-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chemokines in the inflammatory bowel diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902107-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human G protein-coupled receptor GPR-9-6/CC chemokine receptor 9 is selectively expressed on intestinal homing T lymphocytes, mucosal lymphocytes, and thymocytes and is required for thymus-expressed chemokine-mediated chemotaxis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902107-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lymphocyte CC chemokine receptor 9 and epithelial thymus-expressed chemokine (TECK) expression distinguish the small intestinal immune compartment: Epithelial expression of tissue-specific chemokines as an organizing principle in regional immunity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902107-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of epithelial chemoattractants for human intestinal intraepithelial lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902107-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulated production of interferon-inducible T-cell chemoattractants by human intestinal epithelial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902107-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphoinositide 3-kinase: a key biochemical signal for cell migration in response to chemokines.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902107-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein kinases C-gamma and -delta are involved in insulin-like growth factor I-induced migration of colonic epithelial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902107-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distinct pathways of cell migration and antiapoptotic response to epithelial injury: structure-function analysis of human intestinal trefoil factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902107-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intestinal trefoil factor confers colonic epithelial resistance to apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902107-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of phosphatidylinositol 3-kinase by interleukin-13. An inhibitory signal for inducible nitric-oxide synthase expression in epithelial cell line HT-29.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902107-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukins 4 and 13 increase intestinal epithelial permeability by a phosphatidylinositol 3-kinase pathway. Lack of evidence for STAT 6 involvement.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902107-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902107-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Xid-like immunodeficiency in mice with disruption of the p85alpha subunit of phosphoinositide 3-kinase.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902107-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
1-Phosphatidylinositol 3-kinase activity is required for insulin-stimulated glucose transport but not for RAS activation in CHO cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902107-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PI 3-kinase gamma and protein kinase C-zeta mediate RAS-independent activation of MAP kinase by a Gi protein-coupled receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902107-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1471-4914(01)02107-4
1 reference
stated in
Europe PubMed Central
PubMed ID
11597520
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11597520%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
PubMed ID
11597520
1 reference
stated in
Europe PubMed Central
PubMed ID
11597520
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11597520%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
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