(Q34400263)

1 August 2017

Ethanol potentiates HIV-1 gp120-induced apoptosis in human neurons via both the death receptor and NMDA receptor pathways (English)

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1 August 2017

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ChEBI release 2020-05-28

9

Roger J Pomerantz

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1 August 2017

Wei Chen

1

1 reference

1 August 2017

Zhonghua Tang

2

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1 August 2017

Paolo Fortina

3

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1 August 2017

Pritesh Patel

4

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1 August 2017

Sankar Addya

5

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1 August 2017

Saul Surrey

6

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1 August 2017

Edward A Acheampong

7

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1 August 2017

Muhammad Mukhtar

8

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1 August 2017

language of work or name

English

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publication date

1 March 2005

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1 August 2017

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1 August 2017

334

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1 August 2017

1

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1 August 2017

59-73

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Ethanol strongly potentiates apoptosis induced by HIV-1 proteins in primary human brain microvascular endothelial cells

1 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Neurovirulent simian immunodeficiency virus infection induces neuronal, endothelial, and glial apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Neuronal apoptosis in HIV infection in adults

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Alcohol and murine acquired immunodeficiency syndrome suppression of resistance to Cryptosporidium parvum infection during modulation of cytokine production.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Programmed cell death in brains of HIV-1-positive AIDS and pre-AIDS patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Brain-derived neurotrophic factor inhibits human immunodeficiency virus-1/gp120-mediated cerebellar granule cell death by preventing gp120 internalization.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Ethanol pre-exposure suppresses HIV-1 glycoprotein 120-induced neuronal degeneration by abrogating endogenous glutamate/Ca2+-mediated neurotoxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Human immunodeficiency virus type 1 gp120 and ethanol coexposure in rat organotypic brain slice cultures: Curtailment of gp120-induced neurotoxicity and neurotoxic mediators by moderate but not high ethanol concentrations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

CXCR4-activated astrocyte glutamate release via TNFalpha: amplification by microglia triggers neurotoxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Neurotrophic factors BDNF and GDNF protect embryonic chick spinal cord motoneurons from ethanol neurotoxicity in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Chronic ethanol exposure potentiates NMDA excitotoxicity in cerebral cortical neurons.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Development of a human neuronal cell model for human immunodeficiency virus (HIV)-infected macrophage-induced neurotoxicity: apoptosis induced by HIV type 1 primary isolates and evidence for involvement of the Bcl-2/Bcl-xL-sensitive intrinsic apopto

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

HIV-I gpI20 neurotoxicity in brain cultures is prevented by moderate ethanol pretreatment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Ethanol, stroke, brain damage, and excitotoxicity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Is alcohol a cofactor of HIV and AIDS? Evidence from immunological and behavioral studies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Caspase pathways, neuronal apoptosis, and CNS injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

MCP-1 (CCL2) protects human neurons and astrocytes from NMDA or HIV-tat-induced apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Drugs of abuse that cause developing neurons to commit suicide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Microbial Infections, Immunomodulation, and Drugs of Abuse

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Caspase cascades in human immunodeficiency virus-associated neurodegeneration.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Fas ligation induces apoptosis of CD40-activated human B lymphocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

The HIV-1 coat protein gp120 and some of its fragments potently activate native cerebral NMDA receptors mediating neuropeptide release

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

The envelope glycoprotein of human immunodeficiency virus type 1 stimulates release of neurotoxins from monocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Study of receptor-mediated neurotoxins released by HIV-1-infected mononuclear phagocytes found in human brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Inhibition of Insulin-Like Growth Factor-I Signaling by Ethanol in Neuronal Cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Human immunodeficiency virus (HIV) type 1 Vpu induces the expression of CD40 in endothelial cells and regulates HIV-induced adhesion of B-lymphoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Neuronal apoptosis induced by HIV-1 gp120 and the chemokine SDF-1 alpha is mediated by the chemokine receptor CXCR4.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Molecular cloning and characterization of DEFCAP-L and -S, two isoforms of a novel member of the mammalian Ced-4 family of apoptosis proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Increased TUNEL positive cells in human alcoholic brains

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Ethanol-Induced Apoptotic Neurodegeneration and Fetal Alcohol Syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

TRAF5, a novel tumor necrosis factor receptor-associated factor family protein, mediates CD40 signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

AMPA receptor-mediated excitotoxicity in human NT2-N neurons results from loss of intracellular Ca2+ homeostasis following marked elevation of intracellular Na+.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

HIV-1 Tat neurotoxicity is prevented by matrix metalloproteinase inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Pathways to neuronal injury and apoptosis in HIV-associated dementia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Expression of pro- and anti-apoptosis gene products in brains from paediatric patients with HIV-1 encephalitis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

HIV-1 protein Tat induces apoptosis of hippocampal neurons by a mechanism involving caspase activation, calcium overload, and oxidative stress.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

HIV-1 envelope proteins gp120 and gp160 potentiate NMDA-induced [Ca2+]i increase, alter [Ca2+]i homeostasis and induce neurotoxicity in human embryonic neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Ethanol-exposed central neurons fail to migrate and undergo apoptosis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Memantine prevents HIV coat protein-induced neuronal injury in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Seminars in medicine of the Beth Israel Hospital, Boston. Dementia associated with the acquired immunodeficiency syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Synergistic effects of HIV coat protein and NMDA receptor-mediated neurotoxicity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Candidate adaptor protein CED-6 promotes the engulfment of apoptotic cells in C. elegans.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Human CED-6 encodes a functional homologue of the Caenorhabditis elegans engulfment protein CED-6

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Expression of NALP1 in cerebellar granule neurons stimulates apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

The TNF and TNF receptor superfamilies: integrating mammalian biology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Nerve growth factor and basic fibroblast growth factor protect rat cerebellar granule cells in culture against ethanol-induced cell death.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

The pyrin domain: a possible member of the death domain-fold family implicated in apoptosis and inflammation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Dementia in AIDS patients: incidence and risk factors. Multicenter AIDS Cohort Study.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Chemokines regulate hippocampal neuronal signaling and gp120 neurotoxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Neg, a nerve growth factor-stimulated gene expressed by fetal neocortical neurons that is downregulated by ethanol

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Ethanol-induced death of postnatal hippocampal neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

gp120 of HIV-1 induces apoptosis in rat cortical cell cultures: prevention by memantine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Excitotoxic cell death and delayed rescue in human neurons derived from NT2 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Targeted disruption of Traf5 gene causes defects in CD40- and CD27-mediated lymphocyte activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Transfection of C6 glioma cells with glia maturation factor upregulates brain-derived neurotrophic factor and nerve growth factor: trophic effects and protection against ethanol toxicity in cerebellar granule cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Human immunodeficiency virus type 1 Vpr induces apoptosis in human neuronal cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

The human immunodeficiency virus-1 envelope protein gp120 binds through its V3 sequence to the glycine site of N-methyl-D-aspartate receptors mediating noradrenaline release in the hippocampus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Ethanol-induced neurotoxicity is counterbalanced by increased cell proliferation in mouse dentate gyrus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

CD40-mediated signaling in monocytic cells: up-regulation of tumor necrosis factor receptor-associated factor mRNAs and activation of mitogen-activated protein kinase signaling pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Pure, postmitotic, polarized human neurons derived from NTera 2 cells provide a system for expressing exogenous proteins in terminally differentiated neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Effects of HIV-1 Vpr on neuroinvasion and neuropathogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Is p75NGFR involved in developmental neural cell death?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Autoantibodies to glutamate receptor GluR3 in Rasmussen's encephalitis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Hypoxic cell death in human NT2-N neurons: involvement of NMDA and non-NMDA glutamate receptors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Expression of CD40 induces neural apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Morphologic and biochemical hallmarks of apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Alcohol consumption during murine acquired immunodeficiency syndrome accentuates heart pathology due to coxsackievirus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Apoptosis induced by HIV-1 infection of the central nervous system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

The human homologue of Caenorhabditis elegans CED-6 specifically promotes phagocytosis of apoptotic cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Human immunodeficiency virus type 1 Tat protein directly activates neuronal N-methyl-D-aspartate receptors at an allosteric zinc-sensitive site

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Molecular cloning of a novel apoptosis-related gene, human Nap1 (NCKAP1), and its possible relation to Alzheimer disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

CD40 is expressed and functional on neuronal cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Gene expression profiling during the transition to failure in TNF-alpha over-expressing mice demonstrates the development of autoimmune myocarditis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

7 January 2021

Caspases: enemies within

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Prevention of HIV-1 gp120-induced neuronal damage in the central nervous system of transgenic mice by the NMDA receptor antagonist memantine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Recombinant nef HIV-IIIB protein is toxic to human neurons in culture

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

NALPs: a novel protein family involved in inflammation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Activation of the protease-activated thrombin receptor (PAR)-1 induces motoneuron degeneration in the developing avian embryo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Alcohol potentiates HIV-1 infection of human blood mononuclear phagocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Direct cytotoxicity of HIV-1 envelope protein gp120 on human NT neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

HIV-1-mediated apoptosis of neuronal cells: Proximal molecular mechanisms of HIV-1-induced encephalopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Human Nck-associated protein 1 and its binding protein affect the metabolism of beta-amyloid precursor protein with Swedish mutation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Isolation of hNap1BP which interacts with human Nap1 (NCKAP1) whose expression is down-regulated in Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Inhibition of HIV-1 gp120-induced apoptosis in neuroblastoma SK-N-SH cells by an antisense oligodeoxynucleotide against p53.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

An unusual syncytia-inducing human immunodeficiency virus type 1 primary isolate from the central nervous system that is restricted to CXCR4, replicates efficiently in macrophages, and induces neuronal apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Neuroprotective effects of IGF-I against TNFalpha-induced neuronal damage in HIV-associated dementia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Ethanol-induced neuronal apoptosis in vivo requires BAX in the developing mouse brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Fundamental role of the Rip2/caspase-1 pathway in hypoxia and ischemia-induced neuronal cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Intracellular CXCR4 signaling, neuronal apoptosis and neuropathogenic mechanisms of HIV-1-associated dementia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

Characterization of glutamate-induced formation of N-acylphosphatidylethanolamine and N-acylethanolamine in cultured neocortical neurons.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

7 January 2021

Immunobiology of the blood-brain barrier

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

7 January 2021

Neurotoxicity in rat cortical cells caused by N-methyl-D-aspartate (NMDA) and gp120 of HIV-1: induction and pharmacological intervention

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

7 January 2021

Human immunodeficiency virus type 1 Tat protein induces death by apoptosis in primary human neuron cultures.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2005.01.014

7 January 2021

10.1016/J.VIROL.2005.01.014

Identifiers

DOI

1 reference

1 August 2017

1 reference