(Q34405400)

2 August 2017

title

Role of hepatic and intestinal p450 enzymes in the metabolic activation of the colon carcinogen azoxymethane in mice (English)

1 reference

2 August 2017

Vandana Megaraj

1

1 reference

2 August 2017

Xinxin Ding

2

1 reference

2 August 2017

Cheng Fang

3

1 reference

2 August 2017

Nataliia Kovalchuk

4

1 reference

2 August 2017

Yi Zhu

5

1 reference

2 August 2017

Qing-Yu Zhang

6

1 reference

2 August 2017

publication date

5 March 2014

1 reference

Chemical Research in Toxicology

2 August 2017

published in

1 reference

2 August 2017

volume

27

1 reference

2 August 2017

issue

4

1 reference

2 August 2017

page(s)

656-662

1 reference

Role of CYP2A13 in the bioactivation and lung tumorigenicity of the tobacco-specific lung procarcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone: in vivo studies using a CYP2A13-humanized mouse model

2 August 2017

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Expression of two cytochromes P450 involved in carcinogen activation in a human colon cell line

6 July 2018

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Metabolism of azoxymethane, methylazoxymethanol and N-nitrosodimethylamine by cytochrome P450IIE1.

6 July 2018

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6 July 2018

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Metabolic activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone as measured by DNA alkylation in vitro and its inhibition by isothiocyanates

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

1 reference

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Investigations into the metabolism and mode of action of the colon carcinogens 1,2-dimethylhydrazine and azoxymethane

6 July 2018

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6 July 2018

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6 July 2018

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Simultaneous quantitation of 7-methyl- and O6-methylguanine adducts in DNA by liquid chromatography-positive electrospray tandem mass spectrometry

27 October 2018

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In vivo mechanisms of tissue-selective drug toxicity: effects of liver-specific knockout of the NADPH-cytochrome P450 reductase gene on acetaminophen toxicity in kidney, lung, and nasal mucosa

27 October 2018

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Characterization of mouse small intestinal cytochrome P450 expression

27 October 2018

1 reference

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Conditional knockout of the mouse NADPH-cytochrome p450 reductase gene.

27 October 2018

1 reference

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Differential effects of CYP2E1 status on the metabolic activation of the colon carcinogens azoxymethane and methylazoxymethanol.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002058

The role of alcohol dehydrogenase in the metabolism of the colon carcinogen methylazoxymethanol.

27 October 2018

1 reference

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Initial levels of azoxymethane-induced DNA methyl adducts are not predictive of tumor susceptibility in inbred mice.

27 October 2018

1 reference

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Induction of aberrant crypts in murine colon with varying sensitivity to colon carcinogenesis

27 October 2018

1 reference

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Effect of beta-glucuronidase inhibitor on azoxymethane-induced colonic carcinogenesis in rats.

27 October 2018

1 reference

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Production of a highly reactive alkylating agent from the organospecific carcinogen methylazoxymethanol by alcohol dehydrogenase

27 October 2018

1 reference

12 December 2020

In vivo kinetics of O6-methylguanine and 7-methylguanine formation and persistence in DNA of rats treated with symmetrical dimethylhydrazine

1 reference

12 December 2020

Metabolism of the carcinogen 1,2-dimethylhydrazine by isolated human colon microsomes and human colon tumor cells in culture

1 reference

12 December 2020

Characterization of cytochrome P450-dependent dimethylhydrazine metabolism in human colon microsomes

1 reference

12 December 2020

Rat small intestinal cytochromes P450 probed by warfarin metabolism

1 reference

12 December 2020

Rodent models of colon carcinogenesis for the study of chemopreventive activity of natural products

1 reference

12 December 2020

Increased susceptibility of adult rats to azoxymethane-induced aberrant crypt foci

1 reference

12 December 2020

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