(Q34414134)

2 August 2017

title

Novel Rap1 dominant-negative mutants interfere selectively with C3G and Epac (English)

1 reference

2 August 2017

main subject

Rap1 GTPase Dmel_CG1956

1 reference

GOA release 2020-03-11

author name string

Aurélien G Dupuy

1

1 reference

2 August 2017

Sébastien L'Hoste

2

1 reference

2 August 2017

Jacqueline Cherfils

3

1 reference

2 August 2017

Jacques Camonis

4

1 reference

2 August 2017

Georges Gaudriault

5

1 reference

2 August 2017

Jean de Gunzburg

6

1 reference

2 August 2017

language of work or name

English

0 references

publication date

1 June 2005

1 reference

2 August 2017

1 reference

2 August 2017

volume

24

1 reference

2 August 2017

issue

28

1 reference

2 August 2017

page(s)

4509-4520

1 reference

The Rap1 GTPase functions as a regulator of morphogenesis in vivo

2 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

Ras and Rho GTPases: a family reunion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

Association of the Ras-antagonistic Rap1/Krev-1 proteins with the Golgi complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

Structural principles for the multispecificity of small GTP-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

Rap1 up-regulation and activation on plasma membrane regulates T cell adhesion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

The junctional multidomain protein AF-6 is a binding partner of the Rap1A GTPase and associates with the actin cytoskeletal regulator profilin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

The structural basis of the activation of Ras by Sos

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

Epac: a new cAMP target and new avenues in cAMP research

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

Rap1 signalling: adhering to new models

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

Crystal structures of the small G protein Rap2A in complex with its substrate GTP, with GDP and with GTPgammaS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

Characterization of RasGRP2, a plasma membrane-targeted, dual specificity Ras/Rap exchange factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

PDZ-GEF1, a guanine nucleotide exchange factor specific for Rap1 and Rap2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

Three-dimensional structure of an oncogene protein: catalytic domain of human c-H-ras p21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

Dominant inhibitory mutations in the Mg(2+)-binding site of RasH prevent its activation by GTP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

Tools of the trade: use of dominant-inhibitory mutants of Ras-family GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

Rapid Ca2+-mediated activation of Rap1 in human platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

Identification and characterization of RA-GEF-2, a Rap guanine nucleotide exchange factor that serves as a downstream target of M-Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

The Drosophila roughened mutation: activation of a rap homolog disrupts eye development and interferes with cell determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

P element insertion-dependent gene activation in the Drosophila eye.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

Rap1 regulates the formation of E-cadherin-based cell-cell contacts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

Activation of C3G guanine nucleotide exchange factor for Rap1 by phosphorylation of tyrosine 504.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

Activation of the Drosophila C3G leads to cell fate changes and overproliferation during development, mediated by the RAS-MAPK pathway and RAP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

Two types of RAS mutants that dominantly interfere with activators of RAS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

Crucial functions of the Rap1 effector molecule RAPL in lymphocyte and dendritic cell trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

Rap1 GTPase regulation of adherens junction positioning and cell adhesion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

RIAM, an Ena/VASP and Profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

Influence of guanine nucleotides on complex formation between Ras and CDC25 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

RA-GEF, a novel Rap1A guanine nucleotide exchange factor containing a Ras/Rap1A-associating domain, is conserved between nematode and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

RA-GEF-1, a guanine nucleotide exchange factor for Rap1, is activated by translocation induced by association with Rap1*GTP and enhances Rap1-dependent B-Raf activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

Crosstalk between Rap1 and Rac regulates secretion of sAPPalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

A Ral guanine exchange factor-Ral pathway is conserved in Drosophila melanogaster and sheds new light on the connectivity of the Ral, Ras, and Rap pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

Spatio-temporal images of growth-factor-induced activation of Ras and Rap1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

Identification and characterization of potential effector molecules of the Ras-related GTPase Rap2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

Mechanism of the spatio-temporal regulation of Ras and Rap1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

Dominant yeast and mammalian RAS mutants that interfere with the CDC25-dependent activation of wild-type RAS in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

Rap1 regulates E-cadherin-mediated cell-cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

The small GTPase, Rap1, mediates CD31-induced integrin adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

The molecular basis of P-M hybrid dysgenesis: the nature of induced mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

The Saccharomyces cerevisiae SDC25 C-domain gene product overcomes the dominant inhibitory activity of Ha-Ras Asn-17.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

Rap1 mutants with increased affinity for the guanine-nucleotide exchange factor C3G.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

Mutant ras-encoded proteins with altered nucleotide binding exert dominant biological effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

RGS14 is a novel Rap effector that preferentially regulates the GTPase activity of galphao

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

Complex formation between RAS and RAF and other protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

Biochemical characterization of C3G: an exchange factor that discriminates between Rap1 and Rap2 and is not inhibited by Rap1A(S17N).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

Analysis of P transposable element functions in drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

The two-hybrid: an in vivo protein-protein interaction assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208647

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/SJ.ONC.1208647

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/smvhb25pdbazlmj3ijnhnony7e

30 July 2022

mapped directly with Wikidata item

Dimensions Publication ID

1038002311

0 references

Fatcat ID

release_smvhb25pdbazlmj3ijnhnony7e

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/smvhb25pdbazlmj3ijnhnony7e

30 July 2022

mapped directly with Wikidata item

https://api.fatcat.wiki/v0/release/smvhb25pdbazlmj3ijnhnony7e

1 reference

30 July 2022