(Q34420821)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21098093%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

IL-27 supports germinal center function by enhancing IL-21 production and the function of T follicular helper cells (English)

1 reference

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16 January 2020

4

1 reference

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16 January 2020

Patrick Caplazi

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21098093%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Cecile King

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21098093%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Stuart Tangye

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21098093%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Nico Ghilardi

15

1 reference

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16 January 2020

author name string

Marcel Batten

1

1 reference

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16 January 2020

Nandhini Ramamoorthi

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21098093%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Noelyn M Kljavin

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21098093%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Jennifer H Cox

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21098093%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Hart S Dengler

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21098093%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Dimitry M Danilenko

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21098093%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Melanie Wong

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21098093%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

David A Fulcher

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21098093%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Matthew C Cook

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21098093%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Frederic J de Sauvage

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21098093%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

language of work or name

English

0 references

publication date

22 November 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21098093%20AND%20SRC:MED&resulttype=core&format=json

Journal of Experimental Medicine

16 January 2020

published in

1 reference

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16 January 2020

volume

207

1 reference

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16 January 2020

issue

13

1 reference

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16 January 2020

page(s)

2895-2906

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21098093%20AND%20SRC:MED&resulttype=core&format=json

Follicular helper T cell differentiation requires continuous antigen presentation that is independent of unique B cell signaling.

16 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005229

Interferon alpha in systemic lupus erythematosus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005229

IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005229

IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005229

Lineage specification and heterogeneity of T follicular helper cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005229

New insights into the differentiation and function of T follicular helper cells.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005229

Type I interferon signaling in dendritic cells stimulates the development of lymph-node-resident T follicular helper cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005229

Induction of autoimmunity by pristane and other naturally occurring hydrocarbons.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005229

Bcl6 mediates the development of T follicular helper cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005229

Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005229

Cutting edge: IL-27 induces the transcription factor c-Maf, cytokine IL-21, and the costimulatory receptor ICOS that coordinately act together to promote differentiation of IL-10-producing Tr1 cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005229

Neutralization of interferon-alpha/beta-inducible genes and downstream effect in a phase I trial of an anti-interferon-alpha monoclonal antibody in systemic lupus erythematosus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005229

B cell proliferation, somatic hypermutation, class switch recombination, and autoantibody production in ectopic lymphoid tissue in murine lupus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005229

The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005229

Interleukin-6/STAT3 signaling regulates the ability of naive T cells to acquire B-cell help capacities

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005229

Autoreactive IgG memory antibodies in patients with systemic lupus erythematosus arise from nonreactive and polyreactive precursors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005229

A fundamental role for interleukin-21 in the generation of T follicular helper cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005229

Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005229

ICOS controls the pool size of effector-memory and regulatory T cells.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005229

Deficiency of the type I interferon receptor protects mice from experimental lupus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005229

Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndrome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005229

An intense form of homeostatic proliferation of naive CD8+ cells driven by IL-2

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005229

IL-21 has a pathogenic role in a lupus-prone mouse model and its blockade with IL-21R.Fc reduces disease progression.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005229

The biology and therapeutic potential of interleukin 27.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005229

Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005229

Differential effects of IL-27 on human B cell subsets

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005229

The evolution of human anti-double-stranded DNA autoantibodies

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005229

Induction of IgG2a class switching in B cells by IL-27.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005229

WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005229

IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005229

Development of Th1-type immune responses requires the type I cytokine receptor TCCR

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005229

Germinal centers without T cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005229

Transcriptional repression of Stat6-dependent interleukin-4-induced genes by BCL-6: specific regulation of iepsilon transcription and immunoglobulin E switching

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005229

Immunoglobulin D (IgD)-deficient mice reveal an auxiliary receptor function for IgD in antigen-mediated recruitment of B cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005229

Induction of lupus-associated autoantibodies in BALB/c mice by intraperitoneal injection of pristane

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005229

A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells.

6 July 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20100064

S-adenosyl-L-homocysteine hydrolase inactivation curtails ovalbumin-induced immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20100064

Role of CXCR5 and CCR7 in follicular Th cell positioning and appearance of a programmed cell death gene-1high germinal center-associated subpopulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20100064

Loss of IL-7 receptor alpha on CD4+ T cells defines terminally differentiated B cell-helping effector T cells in a B cell-rich lymphoid tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20100064

Early commitment of naïve human CD4(+) T cells to the T follicular helper (T(FH)) cell lineage is induced by IL-12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20100064

Human germinal center T cells are unique Th cells with high propensity for apoptosis induction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20100064

IFN-alpha regulates Toll-like receptor-mediated IL-27 gene expression in human macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20100064

IFN-beta modulates the response to TLR stimulation in human DC: involvement of IFN regulatory factor-1 (IRF-1) in IL-27 gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20100064

Human dendritic cells induce the differentiation of interleukin-21-producing T follicular helper-like cells through interleukin-12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20100064

Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20100064

The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20100064

Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells

21 January 2018

1 reference

12 December 2020

IL-27 induces a Th1 immune response and susceptibility to experimental arthritis

1 reference

12 December 2020

Cutting edge: IL-27 is a potent inducer of IL-10 but not FoxP3 in murine T cells

1 reference

12 December 2020

Suppression of proteoglycan-induced arthritis by anti-CD20 B Cell depletion therapy is mediated by reduction in autoantibodies and CD4+ T cell reactivity

1 reference

12 December 2020

The induction of arthritis in mice by the cartilage proteoglycan aggrecan: roles of CD4+ and CD8+ T cells

1 reference

12 December 2020

Exacerbation of experimental allergic asthma by augmented Th2 responses in WSX-1-deficient mice

1 reference

12 December 2020

Membranous glomerulonephritis development with Th2-type immune deviations in MRL/lpr mice deficient for IL-27 receptor (WSX-1)

1 reference

12 December 2020

Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20100064

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21098093%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21098093%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

PubMed publication ID

21098093

1 reference