(Q34422058)

English

Efficacy and safety of celgosivir in patients with dengue fever (CELADEN): a phase 1b, randomised, double-blind, placebo-controlled, proof-of-concept trial

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scholarly article

1 reference

Europe PubMed Central

2 August 2017

Efficacy and safety of celgosivir in patients with dengue fever (CELADEN): a phase 1b, randomised, double-blind, placebo-controlled, proof-of-concept trial (English)

1 reference

Europe PubMed Central

2 August 2017

1 reference

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Jasmine S Chung

object named as

Jasmine S Chung

15

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object named as

David C Lye

17

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object named as

Eng Eong Ooi

24

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Martin L. Hibberd

object named as

Martin L Hibberd

21

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object named as

Kah Hin Tan

14

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object named as

Yee Sin Leo

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Europe PubMed Central

2 August 2017

Subhash G Vasudevan

object named as

Subhash G Vasudevan

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ORCID Public Data File 2021

object named as

Boon Hian Tan

7

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ORCID Public Data File 2021

1

object named as

Jenny G Low

1 reference

Europe PubMed Central

2 August 2017

Satoru Watanabe

6

object named as

Satoru Watanabe

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Europe PubMed Central

2 August 2017

author name string

Cynthia Sung

2

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Europe PubMed Central

2 August 2017

Limin Wijaya

3

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Europe PubMed Central

2 August 2017

Yuan Wei

4

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Europe PubMed Central

2 August 2017

Abhay P S Rathore

5

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2 August 2017

Liying Toh

8

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Europe PubMed Central

2 August 2017

Lian Tee Chua

9

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Europe PubMed Central

2 August 2017

Yan'an Hou

10

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Europe PubMed Central

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Angelia Chow

11

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2 August 2017

Shiqin Howe

12

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Europe PubMed Central

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Wing Ki Chan

13

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Benjamin P Cherng

16

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Paul A Tambayah

18

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Lee Ching Ng

19

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2 August 2017

John Connolly

20

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Europe PubMed Central

2 August 2017

Yin Bun Cheung

23

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Europe PubMed Central

2 August 2017

publication date

28 May 2014

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Europe PubMed Central

2 August 2017

Lancet Infectious Diseases

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Europe PubMed Central

2 August 2017

14

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Europe PubMed Central

2 August 2017

8

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Europe PubMed Central

2 August 2017

706-715

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2 August 2017

The global distribution and burden of dengue

1 reference

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Surveillance of dengue fever virus: a review of epidemiological models and early warning systems

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Antibodies determine virulence in dengue

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Update on dengue: epidemiology, virus evolution, antiviral drugs, and vaccine development

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Dengue: a continuing global threat

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Cost of dengue cases in eight countries in the Americas and Asia: a prospective study.

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Strategies for development of Dengue virus inhibitors

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Novel approaches to flavivirus drug discovery

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Towards the design of antiviral inhibitors against flaviviruses: the case for the multifunctional NS3 protein from Dengue virus as a target

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Molecular targets for flavivirus drug discovery

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Discovery of insect and human dengue virus host factors

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Host Gene Expression Profiling of Dengue Virus Infection in Cell Lines and Patients

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A randomized controlled trial of chloroquine for the treatment of dengue in Vietnamese adults

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A randomized, double-blind placebo controlled trial of balapiravir, a polymerase inhibitor, in adult dengue patients

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Protective efficacy of the recombinant, live-attenuated, CYD tetravalent dengue vaccine in Thai schoolchildren: a randomised, controlled phase 2b trial

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Identifying protective dengue vaccines: guide to mastering an empirical process

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α-Glucosidase inhibitors as potential broad based anti-viral agents

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Alpha-glucosidase inhibitors reduce dengue virus production by affecting the initial steps of virion morphogenesis in the endoplasmic reticulum

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Celgosivir treatment misfolds dengue virus NS1 protein, induces cellular pro-survival genes and protects against lethal challenge mouse model

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A Dengue Fever Viremia Model in Mice Shows Reduction in Viral Replication and Suppression of the Inflammatory Response after Treatment with Antiviral Drugs

1 reference

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Dose- and schedule-dependent protective efficacy of celgosivir in a lethal mouse model for dengue virus infection informs dosing regimen for a proof of concept clinical trial.

1 reference

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Cost-Effective Real-Time Reverse Transcriptase PCR (RT-PCR) To Screen for Dengue Virus followed by Rapid Single-Tube Multiplex RT-PCR for Serotyping of the Virus

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Detection of Dengue Virus Replication in Peripheral Blood Mononuclear Cells from Dengue Virus Type 2-Infected Patients by a Reverse Transcription-Real-Time PCR Assay

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Serotype-specific detection of dengue viruses in a fourplex real-time reverse transcriptase PCR assay

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New dengue antibody assay with unique differential detection of IgG and IgM antibodies

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Expression and immunoaffinity purification of recombinant dengue virus 2 NS1 protein as a cleavable SUMOstar fusion

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Enzyme-linked immunosorbent assay specific to Dengue virus type 1 nonstructural protein NS1 reveals circulation of the antigen in the blood during the acute phase of disease in patients experiencing primary or secondary infections

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High circulating levels of the dengue virus nonstructural protein NS1 early in dengue illness correlate with the development of dengue hemorrhagic fever

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The early clinical features of dengue in adults: challenges for early clinical diagnosis

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Decision Tree Algorithms Predict the Diagnosis and Outcome of Dengue Fever in the Early Phase of Illness

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Evaluation of the NS1 rapid test and the WHO dengue classification schemes for use as bedside diagnosis of acute dengue fever in adults

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Field evaluation and impact on clinical management of a rapid diagnostic kit that detects dengue NS1, IgM and IgG.

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The magnitude of dengue virus NS1 protein secretion is strain dependent and does not correlate with severe pathologies in the mouse infection model

1 reference

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Evidence That Maternal Dengue Antibodies Are Important in the Development of Dengue Hemorrhagic Fever in Infants

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Identifiers

10.1016/S1473-3099(14)70730-3

1 reference

Europe PubMed Central

2 August 2017

1 reference

Europe PubMed Central

2 August 2017

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