(Q34427722)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028693%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

title

Therapeutic effects of astragaloside IV on myocardial injuries: multi-target identification and network analysis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028693%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

ChEBI release 2020-05-28

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028693%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Weidong Zhang

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028693%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

author name string

Pengyuan Yang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028693%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Fan Li

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028693%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Lin Tao

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028693%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Hong Ding

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028693%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Yaocheng Rui

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028693%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Zhiwei Cao

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028693%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

language of work or name

English

0 references

publication date

17 September 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028693%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028693%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028693%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028693%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

page(s)

e44938

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028693%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

9 March 2020

copyright license

start time

17 September 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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6 July 2018

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6 July 2018

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Network modeling links breast cancer susceptibility and centrosome dysfunction

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6 July 2018

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Cross-talk between epidermal growth factor receptor and hypoxia-inducible factor-1alpha signal pathways increases resistance to apoptosis by up-regulating survivin gene expression

6 July 2018

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6 July 2018

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JAK-STAT pathway in cardiac ischemic stress

6 July 2018

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Scale-free networks in cell biology

6 July 2018

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Role of mitogen-activated protein (MAP) kinases in cardiovascular diseases

6 July 2018

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Cell signalling in the cardiovascular system: an overview

6 July 2018

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Pathways to the analysis of microarray data

6 July 2018

1 reference

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The efficiency of multi-target drugs: the network approach might help drug design

6 July 2018

1 reference

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The mitochondrial death pathway and cardiac myocyte apoptosis

6 July 2018

1 reference

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6 July 2018

Biological robustness

1 reference

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Molecular genetics and genomics of heart failure

6 July 2018

1 reference

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Modularity from fluctuations in random graphs and complex networks.

6 July 2018

1 reference

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Finding and evaluating community structure in networks

6 July 2018

1 reference

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Protein kinase activation and myocardial ischemia/reperfusion injury

6 July 2018

1 reference

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Small G proteins as novel therapeutic targets in cardiovascular medicine

6 July 2018

1 reference

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Crystal structure of human calcineurin complexed with cyclosporin A and human cyclophilin

6 July 2018

1 reference

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Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of immunophilin-drug complexes

6 July 2018

1 reference

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Doxorubicin-induced apoptosis: implications in cardiotoxicity

6 July 2018

1 reference

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Perspective: cardiovascular disease in the postgenomic era--lessons learned and challenges ahead

6 July 2018

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Oxidative pathways in cardiovascular disease: roles, mechanisms, and therapeutic implications.

6 July 2018

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6 July 2018

1 reference

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Emergence of Scaling in Random Networks

6 July 2018

1 reference

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A calcineurin-dependent transcriptional pathway for cardiac hypertrophy

6 July 2018

1 reference

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Moderation of myocardial ischemia reperfusion injury by calcium channel and calmodulin receptor inhibition

6 July 2018

1 reference

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Inhibitory effect of αS1- and αS2-casein hydrolysates on angiotensin I-converting enzyme in human endothelial cells in vitro, rat aortic tissue ex vivo, and renovascular hypertensive rats in vivo

6 July 2018

1 reference

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Valsartan preconditioning protects against myocardial ischemia-reperfusion injury through TLR4/NF-kappaB signaling pathway

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444501

Effects of Astragaloside IV on heart failure in rats

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444501

Astragaloside IV attenuates hypoxia-induced cardiomyocyte damage in rats by upregulating superoxide dismutase-1 levels

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444501

Cartography of complex networks: modules and universal roles.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444501

Astragaloside IV from Astragalus membranaceus shows cardioprotection during myocardial ischemia in vivo and in vitro

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444501

Multiple weak hits confuse complex systems: a transcriptional regulatory network as an example.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444501

Proinflammatory phenotype of vascular smooth muscle cells: role of efficient Toll-like receptor 4 signaling.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444501

Structural details on the binding of antihypertensive drugs captopril and enalaprilat to human testicular angiotensin I-converting enzyme.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444501

Astragaloside IV protects against ischemic brain injury in a murine model of transient focal ischemia

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444501

Tissue distribution of calcineurin and its sensitivity to inhibition by cyclosporine

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444501

Ligand-protein inverse docking and its potential use in the computer search of protein targets of a small molecule

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444501

Angiotensin-converting enzyme (ACE) inhibitors have different selectivity for bradykinin binding sites of human somatic ACE

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444501

Astragaloside IV dilates aortic vessels from normal and spontaneously hypertensive rats through endothelium-dependent and endothelium-independent ways

27 October 2018

1 reference

12 December 2020

Mechanisms underlying vasorelaxant action of astragaloside IV in isolated rat aortic rings

1 reference

12 December 2020

Dual calcium ion regulation of calcineurin by calmodulin and calcineurin B

1 reference

12 December 2020

An improved protocol for primary culture of cardiomyocyte from neonatal mice

1 reference

12 December 2020

Patterned growth of neonatal rat heart cells in culture. Morphological and electrophysiological characterization

1 reference

12 December 2020

Mechanisms of drug combinations: interaction and network perspectives

1 reference

12 December 2020

Novel molecular targets in the treatment of cardiac hypertrophy

1 reference

12 December 2020

Antiinflammatory activity of astragaloside IV is mediated by inhibition of NF-kappaB activation and adhesion molecule expression

1 reference

12 December 2020

In vitro Studies of Single Isolated Beating Heart Cells

1 reference

12 December 2020

Prevention of Cardiac Hypertrophy in Mice by Calcineurin Inhibition

1 reference

12 December 2020

Apoptosis in myocytes in end-stage heart failure

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0044938

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028693%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028693%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

PubMed publication ID

23028693

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028693%20AND%20SRC:MED&resulttype=core&format=json