(Q34438821)

2 August 2017

The hepatitis B virus X protein sensitizes HepG2 cells to UV light-induced DNA damage (English)

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2 August 2017

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1 reference

Alvin T C Lee

1

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2 August 2017

Jianwei Ren

2

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2 August 2017

Ee-Tsin Wong

3

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2 August 2017

Kenneth H K Ban

4

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2 August 2017

Linda A Lee

5

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2 August 2017

Caroline G L Lee

6

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2 August 2017

language of work or name

English

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publication date

30 July 2005

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Journal of Biological Chemistry

2 August 2017

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2 August 2017

280

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2 August 2017

33525-33535

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2 August 2017

39

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Hepatitis B virus. The major etiology of hepatocellular carcinoma

2 August 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

HBx gene of hepatitis B virus induces liver cancer in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Induction of cell cycle progression by hepatitis B virus HBx gene expression in quiescent mouse fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Increased sensitivity to the hepatocarcinogen diethylnitrosamine in transgenic mice carrying the hepatitis B virus X gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

The hepatitis B virus X gene potentiates c-myc-induced liver oncogenesis in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Downregulation of DNA excision repair by the hepatitis B virus-x protein occurs in p53-proficient and p53-deficient cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Expression of hepatitis B virus X protein does not alter the accumulation of spontaneous mutations in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Disruption of the function of tumor-suppressor gene p53 by the hepatitis B virus X protein and hepatocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

p53-dependent cell cycle control: response to genotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

The hepatitis B virus HBx protein inhibits caspase 3 activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Hepatitis B virus X protein inhibits transforming growth factor-beta -induced apoptosis through the activation of phosphatidylinositol 3-kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

The proapoptotic effect of hepatitis B virus HBx protein correlates with its transactivation activity in stably transfected cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Hepatitis B virus X mutants, present in hepatocellular carcinoma tissue abrogate both the antiproliferative and transactivation effects of HBx.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

The hepatitis B virus X gene induces p53-mediated programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

p53-independent apoptotic effects of the hepatitis B virus HBx protein in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Functional inactivation but not structural mutation of p53 causes liver cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Hepatitis B virus X protein and p53 tumor suppressor interactions in the modulation of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Cytoplasmic retention of the p53 tumor suppressor gene product is observed in the hepatitis B virus X gene-transfected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Viral carcinogenesis: revelation of molecular mechanisms and etiology of human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

A simplified system for generating recombinant adenoviruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Expression of the FAT10 gene is highly upregulated in hepatocellular carcinoma and other gastrointestinal and gynecological cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Expression of hepatitis B virus X protein in HBV-infected human livers and hepatocellular carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Hepatitis B virus X protein induces cell death by causing loss of mitochondrial membrane potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Chemotherapeutic drug, adriamycin, restores the function of p53 protein in hepatitis B virus X (HBx) protein-expressing liver cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Pro-apoptotic effect of the hepatitis B virus X gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Increased susceptibility to ultraviolet-B and carcinogens of mice lacking the DNA excision repair gene XPA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

High susceptibility to ultraviolet-induced carcinogenesis in mice lacking XPC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Human hepatitis B virus X protein is detectable in nuclei of transfected cells, and is active for transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Induction of apoptosis after switch-on of the hepatitis B virus X gene mediated by the Cre/loxP recombination system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

p53, the cellular gatekeeper for growth and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Regulation of p53 downstream genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Oncogenic functions of tumour suppressor p21(Waf1/Cip1/Sdi1): association with cell senescence and tumour-promoting activities of stromal fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

GADD45 induction of a G2/M cell cycle checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Mechanisms of G2 arrest in response to overexpression of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Hepatitis B x protein inhibits p53-dependent DNA repair in primary mouse hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Putative role of hepatitis B virus X protein in hepatocarcinogenesis: effects on apoptosis, DNA repair, mitogen-activated protein kinase and JAK/STAT pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Hepatitis B virus X protein inhibits nucleotide excision repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Hepatitis B virus HBx protein sensitizes cells to apoptotic killing by tumor necrosis factor alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Hepatitis B virus HBx protein deregulates cell cycle checkpoint controls

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

HBx protein of hepatitis B virus interacts with the C-terminal portion of a novel human proteasome alpha-subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Cytosol is the prime compartment of hepatitis B virus X protein where it colocalizes with the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

UV-damaged DNA-binding proteins are targets of CUL-4A-mediated ubiquitination and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Turnover of hepatitis B virus X protein is regulated by damaged DNA-binding complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

DDB2 induces nuclear accumulation of the hepatitis B virus X protein independently of binding to DDB1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

p48 Activates a UV-damaged-DNA binding factor and is defective in xeroderma pigmentosum group E cells that lack binding activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Xeroderma pigmentosum p48 gene enhances global genomic repair and suppresses UV-induced mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Hepatitis B virus transactivator protein, HBx, associates with the components of TFIIH and stimulates the DNA helicase activity of TFIIH

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Hepatitis B virus X protein associated with UV-DDB1 induces cell death in the nucleus and is functionally antagonized by UV-DDB2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Natural variants of hepatitis B virus X protein have differential effects on the expression of cyclin-dependent kinase inhibitor p21 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

The p53-mdm2 autoregulatory feedback loop: a paradigm for the regulation of growth control by p53?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Mdm2 promotes the rapid degradation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Regulation of p53 stability by Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

p53 modulation of TFIIH-associated nucleotide excision repair activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Live or let die: the cell's response to p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Control of apoptosis by p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

Apoptosis and viral hepatitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506628200

21 January 2018

Identifiers

DOI

10.1074/JBC.M506628200

1 reference

2 August 2017

1 reference