(Q34442714)

2 August 2017

1 reference

title

α-Synuclein Transgenic Drosophila As a Model of Parkinson's Disease and Related Synucleinopathies (English)

1 reference

2 August 2017

0 references

1 reference

1 reference

Hideya Mizuno

1

1 reference

2 August 2017

Nobuhiro Fujikake

series ordinal

2

1 reference

2 August 2017

Keiji Wada

series ordinal

3

1 reference

2 August 2017

Yoshitaka Nagai

series ordinal

4

1 reference

2 August 2017

publication date

20 December 2010

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2 August 2017

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2 August 2017

volume

2011

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2 August 2017

page(s)

212706

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Creative Commons Attribution 3.0 Unported

2 August 2017

copyright license

start time

1 January 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

cites work

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Pre-fibrillar alpha-synuclein variants with impaired beta-structure increase neurotoxicity in Parkinson's disease models

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease

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6 July 2018

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Small heat shock proteins protect against alpha-synuclein-induced toxicity and aggregation

6 July 2018

1 reference

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The roles of intracellular protein-degradation pathways in neurodegeneration

6 July 2018

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Alpha-synuclein acts in the nucleus to inhibit histone acetylation and promote neurotoxicity

6 July 2018

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Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

6 July 2018

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6 July 2018

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Multiple candidate gene analysis identifies alpha-synuclein as a susceptibility gene for sporadic Parkinson's disease

6 July 2018

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6 July 2018

1 reference

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Multiple regions of alpha-synuclein are associated with Parkinson's disease

6 July 2018

1 reference

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Aggregation promoting C-terminal truncation of alpha-synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations

6 July 2018

1 reference

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Heat shock protein 70 inhibits alpha-synuclein fibril formation via preferential binding to prefibrillar species

6 July 2018

1 reference

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6 July 2018

1 reference

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Parkin counteracts symptoms in a Drosophila model of Parkinson's disease

6 July 2018

1 reference

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Hereditary early-onset Parkinson's disease caused by mutations in PINK1

6 July 2018

1 reference

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Hsp70 Reduces alpha-Synuclein Aggregation and Toxicity

6 July 2018

1 reference

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HSP27 but not HSP70 has a potent protective effect against alpha-synuclein-induced cell death in mammalian neuronal cells.

6 July 2018

1 reference

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Comparison of kindreds with parkinsonism and alpha-synuclein genomic multiplications

6 July 2018

1 reference

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alpha-Synuclein locus triplication causes Parkinson's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010662

Gene expression changes presage neurodegeneration in a Drosophila model of Parkinson's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010662

Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010662

TorsinA and heat shock proteins act as molecular chaperones: suppression of alpha-synuclein aggregation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010662

Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010662

alpha-Synuclein is phosphorylated in synucleinopathy lesions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010662

A systematic analysis of human disease-associated gene sequences in Drosophila melanogaster

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010662

A hydrophobic stretch of 12 amino acid residues in the middle of alpha-synuclein is essential for filament assembly.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010662

A mutation in the ovine cathepsin D gene causes a congenital lysosomal storage disease with profound neurodegeneration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010662

Fiber diffraction of synthetic alpha-synuclein filaments shows amyloid-like cross-beta conformation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010662

A Drosophila model of Parkinson's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010662

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010662

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010662

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010662

Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010662

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010662

Alpha-synuclein in Lewy bodies

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010662

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010662

Pathological biochemistry of alpha-synucleinopathy

6 July 2018

1 reference

https://api.crossref.org/works/10.4061%2F2011%2F212706

Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2011%2F212706

Pharmacological prevention of Parkinson disease in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2011%2F212706

Alpha-synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2011%2F212706

Aggregated alpha-synuclein mediates dopaminergic neurotoxicity in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2011%2F212706

Superoxide dismutase overexpression protects dopaminergic neurons in a Drosophila model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2011%2F212706

Dopamine-dependent neurodegeneration in Drosophila models of familial and sporadic Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2011%2F212706

Induction of the phase II detoxification pathway suppresses neuron loss in Drosophila models of Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2011%2F212706

High doses of nicotinamide prevent oxidative mitochondrial dysfunction in a cellular model and improve motor deficit in a Drosophila model of Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2011%2F212706

Mutant alpha-synuclein-induced degeneration is reduced by parkin in a fly model of Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2011%2F212706

Pink1 suppresses alpha-synuclein-induced phenotypes in a Drosophila model of Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2011%2F212706

Phosphorylation of alpha-synuclein characteristic of synucleinopathy lesions is recapitulated in alpha-synuclein transgenic Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2011%2F212706

Role of alpha-synuclein carboxy-terminus on fibril formation in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2011%2F212706

Identification of the region of non-Abeta component (NAC) of Alzheimer's disease amyloid responsible for its aggregation and toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2011%2F212706

Distinct cleavage patterns of normal and pathologic forms of alpha-synuclein by calpain I in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2011%2F212706

Cleavage of alpha-synuclein by calpain: potential role in degradation of fibrillized and nitrated species of alpha-synuclein.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2011%2F212706

Lifetime proteomic profiling of an A30P alpha-synuclein Drosophila model of Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2011%2F212706

Identification of genes that modify ataxin-1-induced neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2011%2F212706

Effects of pharmacological agents upon a transgenic model of Parkinson's disease in Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2011%2F212706

Alpha-synuclein immunoisolation of glial inclusions from multiple system atrophy brain tissue reveals multiprotein components

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21209707

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4061/2011/212706

1 reference

2 August 2017

1 reference

2 August 2017

1 reference