(Q34444274)

2 August 2017

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title

Biological mechanisms of glioma invasion and potential therapeutic targets (English)

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2 August 2017

B B Tysnes

1

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PubMed ID

11716066

2 August 2017

R Mahesparan

series ordinal

2

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2 August 2017

1 June 2001

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Journal of Neuro-Oncology

2 August 2017

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2 August 2017

53

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2 August 2017

129-147

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2 August 2017

2

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https://scigraph.springernature.com/pub.10.1023/a:1012249216117

2 August 2017

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CD44 mediates human glioma cell adhesion and invasion in vitro.

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Mechanisms of glioma invasion: role of matrix-metalloproteinases

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Distinctive gene expression patterns in human mammary epithelial cells and breast cancers

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Iodine-131-labeled antitenascin monoclonal antibody 81C6 treatment of patients with recurrent malignant gliomas: phase I trial results

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12 December 2020

Clinical and radiographic response in a minority of patients with recurrent malignant gliomas treated with high-dose tamoxifen

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12 December 2020

Effect of epidermal growth factor on glioma cell growth, migration, and invasion in vitro.

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12 December 2020

Expression of integrin alpha v beta 3 in small blood vessels of glioblastoma tumors.

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12 December 2020

Proteomics: new perspectives, new biomedical opportunities

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Neural stem cells are uniquely suited for cell replacement and gene therapy in the CNS.

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12 December 2020

Migratory, invasive and metastatic capacity of NCAM transfected rat glioma cells

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12 December 2020

Role of fibronectin-stimulated tumor cell migration in glioma invasion in vivo: clinical significance of fibronectin and fibronectin receptor expressed in human glioma tissues.

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12 December 2020

Invasive glioma cells in tissue culture

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12 December 2020

Glioma cell interactions with fetal rat brain aggregates in vitro and with brain tissue in vivo.

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12 December 2020

Proteolysis and invasiveness of brain tumors: role of urokinase-type plasminogen activator receptor

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12 December 2020

Expression and localization of urokinase-type plasminogen activator in human astrocytomas in vivo.

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12 December 2020

Genetic alterations associated with glioma progression

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12 December 2020

Matrix metalloproteinases and tissue inhibitors of metalloproteinases in human gliomas

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12 December 2020

Viral vectors for gene therapy

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12 December 2020

Treatment of intracranial human glioma xenografts with 131I-labeled anti-tenascin monoclonal antibody 81C6.

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12 December 2020

Inhibition of human malignant glioma cell motility and invasion in vitro by hypericin, a potent protein kinase C inhibitor

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12 December 2020

A phase I study of high-dose tamoxifen for the treatment of refractory malignant gliomas of childhood.

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12 December 2020

Treatment of recurrent malignant gliomas with chronic oral high-dose tamoxifen.

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12 December 2020

Effect of synthetic matrix-metalloproteinase inhibitors on invasive capacity and proliferation of human malignant gliomas in vitro.

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12 December 2020

Modal DNA content of human intracranial neoplasms studied by flow cytometry.

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12 December 2020

Association of epidermal growth factor receptor gene amplification with loss of chromosome 10 in human glioblastoma multiforme

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12 December 2020

Loco-regional radioimmunotherapy of high-grade malignant gliomas using specific monoclonal antibodies labeled with 90Y: a phase I study.

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Signal transduction by Ras-like GTPases: a potential target for anticancer drugs

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12 December 2020

Expression and cellular localization of messenger RNA for plasminogen activator inhibitor type 1 in human astrocytomas in vivo.

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12 December 2020

Enhanced protein kinase C activity correlates with the growth rate of malignant gliomas in vitro

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12 December 2020

Downregulation of the urokinase-type plasminogen activator receptor through inhibition of translation by antisense oligonucleotide suppresses invasion of human glioblastoma cells

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12 December 2020

Production of matrix metalloproteinases and tissue inhibitor of metalloproteinases-1 by human brain tumors.

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12 December 2020

PTEN gene and integrin signaling in cancer

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12 December 2020

Molecular profile of reactive astrocytes--implications for their role in neurologic disease

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12 December 2020

Transfection of glioma cells with the neural-cell adhesion molecule NCAM: effect on glioma-cell invasion and growth in vivo

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12 December 2020

Determinants of human astrocytoma migration.

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12 December 2020

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

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12 December 2020

Comparison of cell adhesion molecule expression between glioblastoma multiforme and autologous normal brain tissue.

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12 December 2020

Differential display. A general protocol

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12 December 2020

Growth inhibition of astrocytoma cells by farnesyl transferase inhibitors is mediated by a combination of anti-proliferative, pro-apoptotic and anti-angiogenic effects.

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12 December 2020

Long-term culture of organotypic multicellular glioma spheroids: a good culture model for studying gliomas.

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12 December 2020

Neural stem cells display extensive tropism for pathology in adult brain: evidence from intracranial gliomas

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12 December 2020

Animal models for brain tumors: historical perspectives and future directions

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12 December 2020

Extracellular matrix and integrin signalling: the shape of things to come

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12 December 2020

Replication-competent herpes simplex viral vectors for cancer therapy

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12 December 2020

Signaling by integrin receptors

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12 December 2020

Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice

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12 December 2020

Integrin-linked kinase (ILK): a regulator of integrin and growth-factor signalling.

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12 December 2020

Antibody-guided three-step therapy for high grade glioma with yttrium-90 biotin.

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12 December 2020

Subsets of glioblastoma multiforme defined by molecular genetic analysis.

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12 December 2020

Gene therapy for brain tumors

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12 December 2020

PTEN interactions with focal adhesion kinase and suppression of the extracellular matrix-dependent phosphatidylinositol 3-kinase/Akt cell survival pathway

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12 December 2020

Invasion of rat neurogenic cell lines in embryonic chick heart fragments in vitro

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12 December 2020

Heterogeneous response to the growth factors [EGF, PDGF (bb), TGF-alpha, bFGF, IL-2] on glioma spheroid growth, migration and invasion.

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12 December 2020

Migration of brain tumor cells on extracellular matrix proteins in vitro correlates with tumor type and grade and involves alphaV and beta1 integrins.

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12 December 2020

Biological significance of the expression of urokinase-type plasminogen activator receptors (uPARs) in brain tumors

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12 December 2020

A novel model of glioma cell invasion using organotypic brain slice culture.

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12 December 2020

Overexpression of a transmembrane isoform of neural cell adhesion molecule alters the invasiveness of rat CNS-1 glioma

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12 December 2020

Current status of viral gene therapy for brain tumours

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12 December 2020

Overexpression and localization of cathepsin B during the progression of human gliomas.

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12 December 2020

Transfection of an invasive human astrocytoma cell line with a TIMP-1 cDNA: modulation of astrocytoma invasive potential.

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12 December 2020

Epidermal growth factor and laminin receptors contribute to migratory and invasive properties of gliomas.

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12 December 2020

Laminin expression by glial fibrillary acidic protein positive cells in human gliomas

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12 December 2020

Basement membrane invasion of glioma cells mediated by integrin receptors.

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12 December 2020

Vitronectin, a glioma-derived extracellular matrix protein, protects tumor cells from apoptotic death.

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12 December 2020

Stimulation of extracellular matrix components in the normal brain by invading glioma cells

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12 December 2020

Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation

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12 December 2020

Proteins of the Ras pathway as novel potential anticancer therapeutic targets

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12 December 2020

Brain tumor cell invasion, anatomical and biological considerations.

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12 December 2020

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

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12 December 2020

Collagens, integrins and the mesenchymal drift in glioblastomas: a comparison of biopsy specimens, spheroid and early monolayer cultures.

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12 December 2020

Antisense oligonucleotides: an evolving technology for the modulation of gene expression in human disease

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12 December 2020

Paucity of retinoic acid receptor alpha (RAR alpha) nuclear immunostaining in gliomas and inability of retinoic acid to influence neural cell adhesion molecule (NCAM) expression.

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12 December 2020

Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3.

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12 December 2020

Role of high molecular weight extracellular matrix proteins in glioma cell migration

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12 December 2020

Matrix metalloproteinases and tissue inhibitor of metalloproteinases: a review of their role in tumorigenesis and tissue invasion

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12 December 2020

Tumor invasion, proteolysis, and angiogenesis

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12 December 2020

Fibronectin-mediated cell migration promotes glioma cell invasion through chemokinetic activity.

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12 December 2020

Cytogenetics and Molecular Genetics of Malignant Gliomas and Medulloblastoma

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12 December 2020

Tumor cell interactions with the extracellular matrix during invasion and metastasis

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12 December 2020

The role of extracellular matrix in human astrocytoma migration and proliferation studied in a microliter scale assay.

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12 December 2020

Distinct patterns of deletion on 10p and 10q suggest involvement of multiple tumor suppressor genes in the development of astrocytic gliomas of different malignancy grades.

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12 December 2020

Gene Amplification in Malignant Human Gliomas: Clinical and Histopathologic Aspects

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12 December 2020

Migration arrest in glioma cells is dependent on the alphav integrin subunit

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12 December 2020

Elevated levels of urokinase-type plasminogen activator and plasminogen activator inhibitor type-1 in malignant human brain tumors.

1 reference

12 December 2020

A comparison of the relative chemosensitivity of human gliomas to tamoxifen and n-desmethyltamoxifen in vitro.

1 reference

12 December 2020

Extracellular matrix-induced cell migration from glioblastoma biopsy specimens in vitro.

1 reference

12 December 2020

Regional localization of a glioma-associated antigen defined by monoclonal antibody 81C6 in vivo: kinetics and implications for diagnosis and therapy.

1 reference

12 December 2020

Adenovirus-mediated delivery of antisense gene to urokinase-type plasminogen activator receptor suppresses glioma invasion and tumor growth.

1 reference

12 December 2020

Serial analysis of gene expression

1 reference

12 December 2020

Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction

1 reference

12 December 2020

The extracellular matrix of the central and peripheral nervous systems: structure and function

1 reference

12 December 2020

Salvage chemotherapy with tamoxifen for recurrent anaplastic astrocytomas.

1 reference

12 December 2020

Structure of human pro-matrix metalloproteinase-2: activation mechanism revealed

1 reference

12 December 2020

Astrocytes give rise to oligodendrogliomas and astrocytomas after gene transfer of polyoma virus middle T antigen in vivo

1 reference

12 December 2020

Diffuse brain invasion of glioma cells requires beta 1 integrins

1 reference

12 December 2020

Growth factor regulation of integrin-mediated cell motility

1 reference

12 December 2020

Expression of adhesion factors and degrading proteins in primary and secondary glioblastomas and their precursor tumors

1 reference

12 December 2020

Tumor cell invasion and gap junctional communication. II. Normal and malignant cells confronted in multicell spheroids

1 reference

12 December 2020

Tracking the invasiveness of human astrocytoma cells by using green fluorescent protein in an organotypical brain slice model

1 reference

12 December 2020

Tumor suppressor PTEN inhibition of cell invasion, migration, and growth: differential involvement of focal adhesion kinase and p130Cas.

1 reference

12 December 2020

Systematic variation in gene expression patterns in human cancer cell lines

1 reference

12 December 2020

Cathepsin B expression and localization in glioma progression and invasion.

1 reference

12 December 2020

A rapid in vitro assay for quantitating the invasive potential of tumor cells

1 reference

12 December 2020

Tenascin mediates human glioma cell migration and modulates cell migration on fibronectin

1 reference

12 December 2020

Molecular genetic characterization of CNS tumor oncogenesis

1 reference

12 December 2020

Recent insights into the role of integrins in cancer metastasis.

1 reference

12 December 2020

The treatment of intracranial malignant gliomas using orally administered tamoxifen therapy: preliminary results in a series of "failed" patients

1 reference

12 December 2020

Preparation and characterization of anti-tenascin monoclonal antibody-streptavidin conjugates for pretargeting applications.

1 reference

12 December 2020

Expression and role of cadherins in astrocytic tumors.

1 reference

12 December 2020

Therapeutic efficacy of antiglioma mesenchymal extracellular matrix 131I-radiolabeled murine monoclonal antibody in a human glioma xenograft model.

1 reference

12 December 2020

The role of protein kinase C in migration of rat glioma cells from spheroid cultures.

1 reference

12 December 2020

Phase I evaluation of ISIS 3521, an antisense oligodeoxynucleotide to protein kinase C-alpha, in patients with advanced cancer

1 reference

12 December 2020

Towards a structural model of an integrin

1 reference

12 December 2020

Tenascin-C expression by angiogenic vessels in human astrocytomas and by human brain endothelial cells in vitro

1 reference

12 December 2020

Altered gene expression in human astrocytoma cells selected for migration: I. Thromboxane synthase

1 reference

12 December 2020

Cathepsin B expression in human tumors

1 reference

12 December 2020

Changing views of the role of matrix metalloproteinases in metastasis

1 reference

12 December 2020

Hyaluronan and hyaluronectin in the extracellular matrix of human brain tumour stroma.

1 reference

12 December 2020

Growth of precultured human glioma specimens in nude rat brain

1 reference

12 December 2020

Inhibition of Ras farnesylation by lovastatin leads to downregulation of proliferation and migration in primary cultured human glioblastoma cells.

1 reference

12 December 2020

Comprehensive allelotype and genetic anaysis of 466 human nervous system tumors

1 reference

12 December 2020

Signal transduction by integrins and its role in the regulation of tumor growth

1 reference

12 December 2020

The normal structure and function of CD44 and its role in neoplasia

1 reference

12 December 2020

Signal transduction for proliferation of glioma cells in vitro occurs predominantly through a protein kinase C-mediated pathway.

1 reference

12 December 2020

Genetics and malignant progression of human brain tumours.

1 reference

12 December 2020

Expression of matrix metalloproteinases and their tissue inhibitors in human brain tumors

1 reference

12 December 2020

Development of experimental models for meningeal neoplasia using intrathecal injection of 9L gliosarcoma and Walker 256 carcinosarcoma in the rat.

1 reference

12 December 2020

Expression of tissue inhibitors of metalloproteinases: negative regulators of human glioblastoma invasion in vivo.

1 reference

12 December 2020

Signal transduction by cell adhesion receptors

1 reference

12 December 2020

Thromboxane synthase regulates the migratory phenotype of human glioma cells

1 reference

12 December 2020

Correlation of DNA ploidy and morphological features of human glioma cell cultures with the establishment of cell lines.

1 reference

12 December 2020

Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN

1 reference

12 December 2020

The urokinase/urokinase-receptor system and cancer invasion

1 reference

12 December 2020

Proliferation of human malignant astrocytomas is dependent on Ras activation.

1 reference

12 December 2020

Integrins: versatility, modulation, and signaling in cell adhesion

1 reference

12 December 2020

Role of alphavbeta3 integrin in the activation of vascular endothelial growth factor receptor-2.

1 reference

12 December 2020

Invasive behaviour of human gliomas is mediated by interindividually different integrin patterns.

1 reference

12 December 2020

The role of integrins in the malignant phenotype of gliomas

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12 December 2020

10 nm filaments in normal and transformed cells

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12 December 2020

A model for xenotransplantation of human malignant astrocytomas into the brain of normal adult rats

1 reference

12 December 2020

Effects of EGF, bFGF, NGF and PDGF(bb) on cell proliferative, migratory and invasive capacities of human brain-tumour biopsies in vitro.

1 reference

12 December 2020

Tumor cell invasion and angiogenesis in the central nervous system

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12 December 2020

Phenotypic properties of neoplastic cell lines developed from fetal rat brain cells in culture after exposure to ethylnitrosourea in vivo

1 reference

12 December 2020

Extracellular matrix proteins inhibit proliferation, upregulate migration and induce morphological changes in human glioma cell lines.

1 reference

12 December 2020

Heterogeneous regional expression patterns of matrix metalloproteinases in human malignant gliomas.

1 reference

12 December 2020

The p21-Ras signal transduction pathway and growth regulation in human high-grade gliomas

1 reference

12 December 2020

Leptomeningeal tissue: a barrier against brain tumor cell invasion

1 reference

12 December 2020

131I radioconjugated antibodies for the locoregional radioimmunotherapy of high-grade malignant glioma--phase I and II study

1 reference

12 December 2020

Integrin alpha3beta1-mediated interaction with laminin-5 stimulates adhesion, migration and invasion of malignant glioma cells.

1 reference

12 December 2020

Extracellular matrix-degrading proteinases in the nervous system

1 reference

12 December 2020

Development and malignant progression of astrocytomas in GFAP-v-src transgenic mice

1 reference

12 December 2020

Immunolocalization of cathepsin B in human glioma: implications for tumor invasion and angiogenesis

1 reference

12 December 2020

Inhibition of protein kinase C by tamoxifen.

1 reference

12 December 2020

Multicellular tumor spheroids from human gliomas maintained in organ culture

1 reference

12 December 2020

Signal transduction pathways and their relevance in human astrocytomas

1 reference

12 December 2020

Domains of laminin with growth-factor activity

1 reference

12 December 2020

Glioblastoma expression of vitronectin and the alpha v beta 3 integrin. Adhesion mechanism for transformed glial cells

1 reference

12 December 2020

Role of integrins in cancer: survey of expression patterns

1 reference

12 December 2020

Rat brain tumor models in experimental neuro-oncology: the 9L, C6, T9, F98, RG2 (D74), RT-2 and CNS-1 gliomas

1 reference

12 December 2020

The cytoskeleton and brain tumour cell migration.

1 reference

12 December 2020

Stimulation of glioma-cell migration by laminin and inhibition by anti-alpha3 and anti-beta1 integrin antibodies

1 reference

12 December 2020

Induction of transforming growth factor beta 1 in human breast cancer in vivo following tamoxifen treatment

1 reference

12 December 2020

Adhesion and migration of human glioma cells are differently dependent on extracellular matrix molecules.

1 reference

12 December 2020

Effects of growth factors on a human glioma cell line during invasion into rat brain aggregates in culture

1 reference

12 December 2020

[Cancerogenic effects of methyl- and ethyl-nitrosourea (MNU and ENU) at single intracerebral and intracarotidal injection in newborn and young BD-rats]

1 reference

12 December 2020

Differential effects of vincristine and phenytoin on the proliferation, migration, and invasion of human glioma cell lines.

1 reference

12 December 2020

Genome-wide analysis of DNA copy-number changes using cDNA microarrays

1 reference

12 December 2020

Guilt-by-association goes global

1 reference

12 December 2020

Tenascin expression in astrocytomas correlates with angiogenesis

1 reference

12 December 2020

Characterization of integrin receptors in normal and neoplastic human brain.

1 reference

12 December 2020

Morphological and immunochemical studies of rat glial tumors and clonal strains propagated in culture

1 reference

12 December 2020

Shc and FAK differentially regulate cell motility and directionality modulated by PTEN.

1 reference

12 December 2020

Genetic alterations associated with the evolution and progression of astrocytic brain tumours

1 reference

12 December 2020

Differential expression of the CD44 molecule in human brain tumours.

1 reference

12 December 2020

Phase I study of an antisense oligonucleotide to protein kinase C-alpha (ISIS 3521/CGP 64128A) in patients with cancer

1 reference

12 December 2020

Essay: Amersham Pharmacia Biotech & Science prize. Tantalizing transcriptomes--SAGE and its use in global gene expression analysis.

1 reference

12 December 2020

Proliferation, migration and invasion of human glioma cells exposed to paclitaxel (Taxol) in vitro

1 reference

12 December 2020

Clonal genomic alterations in glioma malignancy stages.

1 reference

12 December 2020

Identification of a glioblastoma-associated tenascin-C isoform by a high affinity recombinant antibody

1 reference

12 December 2020

Identifiers

DOI

10.1023/A:1012249216117

1 reference

PubMed ID

11716066

Dimensions Publication ID

2 August 2017

0 references

1 reference

PubMed ID

11716066