Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q34464179)
Watch
English
The relationship of autophagy defects to cartilage damage during joint aging in a mouse model.
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
4446178
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25708836%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
title
The relationship of autophagy defects to cartilage damage during joint aging in a mouse model
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
4446178
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25708836%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
main subject
autophagy
0 references
cartilage
1 reference
based on heuristic
inferred from title
author
Beatriz Carames
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
4446178
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25708836%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
author name string
Merissa Olmer
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
4446178
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25708836%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
William B Kiosses
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
4446178
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25708836%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
Martin K Lotz
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
4446178
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25708836%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
publication date
1 June 2015
1 reference
stated in
Europe PubMed Central
PMC publication ID
4446178
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25708836%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
published in
Arthritis & Rheumatology
1 reference
stated in
Europe PubMed Central
PMC publication ID
4446178
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25708836%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
volume
67
1 reference
stated in
Europe PubMed Central
PMC publication ID
4446178
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25708836%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
issue
6
1 reference
stated in
Europe PubMed Central
PMC publication ID
4446178
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25708836%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
page(s)
1568-1576
1 reference
stated in
Europe PubMed Central
PMC publication ID
4446178
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25708836%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
cites work
Proteostasis and the aging proteome in health and disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
Dysregulated FOXO transcription factors in articular cartilage in aging and osteoarthritis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
Histopathology of naturally occurring and surgically induced osteoarthritis in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
Effects of aging on articular cartilage homeostasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
Osteoarthritis: a disease of the joint as an organ
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
Autophagy activation by rapamycin reduces severity of experimental osteoarthritis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
Mechanical injury suppresses autophagy regulators and pharmacologic activation of autophagy results in chondroprotection.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
Autophagy and aging
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
Autophagy and cartilage homeostasis mechanisms in joint health, aging and OA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
Chondrocyte AMP-activated protein kinase activity suppresses matrix degradation responses to proinflammatory cytokines interleukin-1β and tumor necrosis factor α.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
Regulation of mammalian autophagy in physiology and pathophysiology.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the mouse.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
Can autophagy promote longevity?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
Epidemiology of osteoarthritis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
Short-term fasting induces profound neuronal autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
AMPK inhibition in health and disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
The complexes of mammalian target of rapamycin.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
Macroscopic assessment of cartilage shear: effects of counter-surface roughness, synovial fluid lubricant, and compression offset
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
Autophagy during cardiac stress: joys and frustrations of autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
Methods in mammalian autophagy research
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
Chondrocyte autophagy is stimulated by HIF-1 dependent AMPK activation and mTOR suppression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
Physiological functions of autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
Oxidative stress inhibits insulin-like growth factor-I induction of chondrocyte proteoglycan synthesis through differential regulation of phosphatidylinositol 3-Kinase-Akt and MEK-ERK MAPK signaling pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
The regulation of aging: does autophagy underlie longevity?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
Rapamycin protects against rotenone-induced apoptosis through autophagy induction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
Regulation of autophagy in human and murine cartilage: hypoxia-inducible factor 2 suppresses chondrocyte autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
Aging-related loss of the chromatin protein HMGB2 in articular cartilage is linked to reduced cellularity and osteoarthritis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
Autophagic cell death: the story of a misnomer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
Lifetime risk of symptomatic knee osteoarthritis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
Restoration of chaperone-mediated autophagy in aging liver improves cellular maintenance and hepatic function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
HIF-1 regulation of chondrocyte apoptosis: induction of the autophagic pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
Sexual dimorphism in the osteoarthritis of STR/ort mice may be linked to articular cytokines
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
Grading of chronic synovitis--a histopathological grading system for molecular and diagnostic pathology
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
Damage to type II collagen in aging and osteoarthritis starts at the articular surface, originates around chondrocytes, and extends into the cartilage with progressive degeneration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
6 July 2018
Transcriptional regulation of endochondral ossification by HIF-2alpha during skeletal growth and osteoarthritis development.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FART.39073
retrieved
21 January 2018
Cartilage-specific deletion of mTOR upregulates autophagy and protects mice from osteoarthritis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4446178
retrieved
27 October 2018
Intra-articular administration of gelatin hydrogels incorporating rapamycin-micelles reduces the development of experimental osteoarthritis in a murine model
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25708836
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Hypoxia-inducible factor-2alpha is a catabolic regulator of osteoarthritic cartilage destruction
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25708836
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1002/ART.39073
1 reference
stated in
Europe PubMed Central
PMC publication ID
4446178
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25708836%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
PMC publication ID
4446178
1 reference
stated in
Europe PubMed Central
PMC publication ID
4446178
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25708836%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
PubMed publication ID
25708836
1 reference
stated in
Europe PubMed Central
PMC publication ID
4446178
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25708836%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
ResearchGate publication ID
272754848
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit