(Q34466731)

2 August 2017

title

Disruption of DNA-methylation-dependent long gene repression in Rett syndrome (English)

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2 August 2017

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7

Martin Hemberg

1 reference

2 August 2017

Harrison W Gabel

1

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2 August 2017

Benyam Kinde

2

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2 August 2017

Hume Stroud

3

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2 August 2017

Caitlin S Gilbert

4

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2 August 2017

David A Harmin

5

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2 August 2017

Nathaniel R Kastan

6

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2 August 2017

Daniel H Ebert

8

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2 August 2017

Michael E Greenberg

9

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2 August 2017

language of work or name

English

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publication date

11 March 2015

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2 August 2017

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2 August 2017

volume

522

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2 August 2017

issue

7554

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2 August 2017

page(s)

89-93

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https://scigraph.springernature.com/pub.10.1038/nature14319

2 August 2017

exact match

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cites work

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Global transcriptional and translational repression in human-embryonic-stem-cell-derived Rett syndrome neurons

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6 July 2018

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6 July 2018

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Loss of MeCP2 function is associated with distinct gene expression changes in the striatum

6 July 2018

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6 July 2018

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Activity-dependent phosphorylation of MeCP2 threonine 308 regulates interaction with NCoR.

6 July 2018

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Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor

6 July 2018

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An AT-hook domain in MeCP2 determines the clinical course of Rett syndrome and related disorders

6 July 2018

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MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system.

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Base-resolution analyses of sequence and parent-of-origin dependent DNA methylation in the mouse genome

6 July 2018

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Crh and Oprm1 mediate anxiety-related behavior and social approach in a mouse model of MECP2 duplication syndrome

6 July 2018

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5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging

6 July 2018

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6 July 2018

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FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism

6 July 2018

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6 July 2018

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6 July 2018

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Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43.

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4480648

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6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4480648

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6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4480648

Widespread transcription at neuronal activity-regulated enhancers

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4480648

Neuronal MeCP2 is expressed at near histone-octamer levels and globally alters the chromatin state.

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4480648

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6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4480648

The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4480648

Mouse models of MeCP2 disorders share gene expression changes in the cerebellum and hypothalamus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4480648

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6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4480648

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6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4480648

MeCP2, a key contributor to neurological disease, activates and represses transcription

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4480648

The story of Rett syndrome: from clinic to neurobiology

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4480648

Cerebellar gene expression profiles of mouse models for Rett syndrome reveal novel MeCP2 targets

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4480648

Brain-specific phosphorylation of MeCP2 regulates activity-dependent Bdnf transcription, dendritic growth, and spine maturation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4480648

A multivariate two-sample mean test for small sample size and missing data

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4480648

Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2).

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4480648

Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4480648

Derepression of BDNF Transcription Involves Calcium-Dependent Phosphorylation of MeCP2

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4480648

Transcriptional profiling of a mouse model for Rett syndrome reveals subtle transcriptional changes in the brain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4480648

Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4480648

Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4480648

Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4480648

Submicroscopic duplication in Xq28 causes increased expression of the MECP2 gene in a boy with severe mental retardation and features of Rett syndrome

6 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14319

Mild overexpression of MeCP2 causes a progressive neurological disorder in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14319

FXYD1 is an MeCP2 target gene overexpressed in the brains of Rett syndrome patients and Mecp2-null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14319

Disease modeling using embryonic stem cells: MeCP2 regulates nuclear size and RNA synthesis in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14319

Production and purification of lentiviral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14319

Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14319

21 January 2018

Identifiers

DOI

10.1038/NATURE14319

1 reference

Dimensions Publication ID

2 August 2017

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2 August 2017

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