(Q34509804)

2 August 2017

title

Human telomere biology: A contributory and interactive factor in aging, disease risks, and protection (English)

1 reference

2 August 2017

1

Elizabeth H Blackburn

1 reference

2 August 2017

2

Elissa S Epel

1 reference

2 August 2017

3

Jue Lin

1 reference

2 August 2017

language of work or name

English

0 references

publication date

1 December 2015

1 reference

2 August 2017

1 reference

2 August 2017

volume

350

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2 August 2017

issue

6265

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2 August 2017

page(s)

1193-1198

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Preferential accumulation of single-stranded regions in telomeres of human fibroblasts

2 August 2017

cites work

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Leucocyte telomere length and risk of cardiovascular disease: systematic review and meta-analysis

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Essential role of limiting telomeres in the pathogenesis of Werner syndrome

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Determinants of telomere attrition over 1 year in healthy older women: stress and health behaviors matter

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Transcriptional outcome of telomere signalling

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Peripheral blood leukocyte telomere length and mortality among 64,637 individuals from the general population

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

A genome-wide association study identifies a locus on chromosome 14q21 as a predictor of leukocyte telomere length and as a marker of susceptibility for bladder cancer

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Telomere dysfunction as a cause of genomic instability in Werner syndrome

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Telomere dysfunction accurately predicts clinical outcome in chronic lymphocytic leukaemia, even in patients with early stage disease

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

The unusual telomeres of Drosophila.

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Telomere length predicts survival independent of genetic influences

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

A non-genetic, epigenetic-like mechanism of telomere length inheritance?

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Telomeres and early-life stress: an overview

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

trt-1 is the Caenorhabditis elegans catalytic subunit of telomerase

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Telomeres and lifestyle factors: roles in cellular aging

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Telomere dysfunction causes alveolar stem cell failure

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Telomere Length Shortening and Alzheimer Disease--A Mendelian Randomization Study

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Automated Assay of Telomere Length Measurement and Informatics for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Role of telomere dysfunction in cardiac failure in Duchenne muscular dystrophy

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Longer leukocyte telomere length in Costa Rica's Nicoya Peninsula: a population-based study

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

The telomere syndromes

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Association of relative telomere length with progression of chronic kidney disease in two cohorts: effect modification by smoking and diabetes

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Unraveling the pathogenesis of Hoyeraal-Hreidarsson syndrome, a complex telomere biology disorder

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Taking the brakes off telomerase

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Telomere dysfunction induces metabolic and mitochondrial compromise.

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Telomeres and age-related disease: how telomere biology informs clinical paradigms

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Telomerase protects Werner syndrome lineage-specific stem cells from premature aging.

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Association between telomere length and type 2 diabetes mellitus: a meta-analysis

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Association between telomere length and experimentally induced upper respiratory viral infection in healthy adults

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Telomerase mutations in smokers with severe emphysema.

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Association of TERC and OBFC1 haplotypes with mean leukocyte telomere length and risk for coronary heart disease

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Psychiatric disorders and leukocyte telomere length: Underlying mechanisms linking mental illness with cellular aging

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Genetic variants in telomerase-related genes are associated with an older age at diagnosis in glioma patients: evidence for distinct pathways of gliomagenesis

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

The association of telomere length and cancer: a meta-analysis

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Advances in the understanding of dyskeratosis congenita

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Leukocyte telomere length and mortality in the National Health and Nutrition Examination Survey, 1999-2002

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Telomere dynamics may link stress exposure and ageing across generations

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Early telomerase inactivation accelerates aging independently of telomere length

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Reduced telomerase activity in human T lymphocytes exposed to cortisol

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

The telomere deprotection response is functionally distinct from the genomic DNA damage response.

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Short telomeres compromise β-cell signaling and survival

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Stress exposure in intrauterine life is associated with shorter telomere length in young adulthood

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Triallelic and epigenetic-like inheritance in human disorders of telomerase

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Glucose substitution prolongs maintenance of energy homeostasis and lifespan of telomere dysfunctional mice

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Identification of seven loci affecting mean telomere length and their association with disease

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

How shelterin protects mammalian telomeres

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

The heritability of leucocyte telomere length dynamics

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Fifteen-year follow-up of association between telomere length and incident cancer and cancer mortality

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

A platform for rapid exploration of aging and diseases in a naturally short-lived vertebrate.

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Premature aging in telomerase-deficient zebrafish

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Depressive symptoms and short telomere length are associated with increased mortality in bladder cancer patients.

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Telomere shortening exposes functions for the mouse Werner and Bloom syndrome genes

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Removal of shelterin reveals the telomere end-protection problem

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

TERT promoter mutations in familial and sporadic melanoma

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

The association between depression and leukocyte telomere length: a meta-analysis.

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Telomeres and telomerase: the path from maize, Tetrahymena and yeast to human cancer and aging

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Influence of mindfulness-based stress reduction (MBSR) on telomerase activity in women with breast cancer (BC).

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Shortened telomere length is associated with increased risk of cancer: a meta-analysis

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Telomere length and cortisol reactivity in children of depressed mothers

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Poor maternal nutrition followed by accelerated postnatal growth leads to alterations in DNA damage and repair, oxidative and nitrosative stress, and oxidative defense capacity in rat heart

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.AAB3389

Identifiers

DOI

10.1126/SCIENCE.AAB3389

1 reference

2 August 2017

1 reference