(Q34520528)

2 August 2017

title

Programmed necrosis in inflammation: Toward identification of the effector molecules (English)

1 reference

2 August 2017

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Douglas R Green

4

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author name string

David Wallach

series ordinal

1

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2 August 2017

Tae-Bong Kang

series ordinal

2

1 reference

2 August 2017

Christopher P Dillon

series ordinal

3

1 reference

2 August 2017

language of work or name

English

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publication date

1 April 2016

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2 August 2017

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2 August 2017

volume

352

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2 August 2017

issue

6281

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2 August 2017

page(s)

aaf2154

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Programmed cell death and apoptosis: origins of the theory.

2 August 2017

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A whodunit: an appointment with death

21 January 2018

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Conservation of caspase substrates across metazoans suggests hierarchical importance of signaling pathways over specific targets and cleavage site motifs in apoptosis

21 January 2018

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Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF

21 January 2018

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Mitochondria and cell death: outer membrane permeabilization and beyond

21 January 2018

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Many players in BCL-2 family affairs

21 January 2018

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Biochemical pathways of caspase activation during apoptosis

21 January 2018

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The death domain superfamily in intracellular signaling of apoptosis and inflammation

21 January 2018

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Cytotoxicity mediated by soluble antigen and lymphocytes in delayed hypersensitivity. 3. Analysis of mechanism

21 January 2018

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Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule

21 January 2018

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Identification of RIP1 kinase as a specific cellular target of necrostatins

21 January 2018

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Interferon-induced RIP1/RIP3-mediated necrosis requires PKR and is licensed by FADD and caspases

21 January 2018

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RIPK1 blocks early postnatal lethality mediated by caspase-8 and RIPK3

21 January 2018

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Toll-like receptor 3-mediated necrosis via TRIF, RIP3, and MLKL.

21 January 2018

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DAI/ZBP1/DLM-1 complexes with RIP3 to mediate virus-induced programmed necrosis that is targeted by murine cytomegalovirus vIRA.

21 January 2018

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Direct activation of RIP3/MLKL-dependent necrosis by herpes simplex virus 1 (HSV-1) protein ICP6 triggers host antiviral defense

21 January 2018

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RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis

21 January 2018

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Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation

21 January 2018

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Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha

21 January 2018

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Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor.

21 January 2018

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Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis

21 January 2018

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The Ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs

21 January 2018

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Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase

21 January 2018

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Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis

21 January 2018

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The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism

21 January 2018

1 reference

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Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death

21 January 2018

1 reference

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Translocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell death

21 January 2018

1 reference

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Mixed lineage kinase domain-like protein MLKL causes necrotic membrane disruption upon phosphorylation by RIP3.

21 January 2018

1 reference

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RIPK3 contributes to TNFR1-mediated RIPK1 kinase-dependent apoptosis in conditions of cIAP1/2 depletion or TAK1 kinase inhibition

21 January 2018

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Activity of protein kinase RIPK3 determines whether cells die by necroptosis or apoptosis

21 January 2018

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RIP3 induces apoptosis independent of pronecrotic kinase activity

21 January 2018

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The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways

21 January 2018

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CaMKII is a RIP3 substrate mediating ischemia- and oxidative stress-induced myocardial necroptosis.

21 January 2018

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Necroptosis and its role in inflammation

21 January 2018

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Concerning the mechanism of action of interferon

21 January 2018

1 reference

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Increase of vulnerability to lymphotoxin in cells infected by vesicular stomatitis virus and its further augmentation by interferon

21 January 2018

1 reference

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Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria.

21 January 2018

1 reference

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Pyroptotic cell death defends against intracellular pathogens

21 January 2018

1 reference

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Inflammatory stimuli regulate caspase substrate profiles

21 January 2018

1 reference

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Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.

21 January 2018

1 reference

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Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

21 January 2018

1 reference

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Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

21 January 2018

1 reference

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Control of life-or-death decisions by RIP1 kinase

21 January 2018

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The extrinsic cell death pathway and the élan mortel

21 January 2018

1 reference

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The two faces of receptor interacting protein kinase-1

21 January 2018

1 reference

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RIPK1 and NF-κB signaling in dying cells determines cross-priming of CD8⁺ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF2154

Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF2154

RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF2154

The necroptosis adaptor RIPK3 promotes injury-induced cytokine expression and tissue repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF2154

Nonapoptotic functions of caspases: caspases as regulatory molecules for immunity and cell-fate determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF2154

Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF2154

Caspase-11 controls interleukin-1β release through degradation of TRPC1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF2154

The in vivo significance of necroptosis: lessons from exploration of caspase-8 function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF2154

MLKL compromises plasma membrane integrity by binding to phosphatidylinositol phosphates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF2154

Diverse sequence determinants control human and mouse receptor interacting protein 3 (RIP3) and mixed lineage kinase domain-like (MLKL) interaction in necroptotic signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF2154

Necroptosis is preceded by nuclear translocation of the signaling proteins that induce it.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF2154

21 January 2018

Identifiers

DOI

10.1126/SCIENCE.AAF2154

1 reference

2 August 2017

1 reference