(Q34533270)

2 August 2017

title

Population kinetics, efficacy, and safety of dichloroacetate for lactic acidosis due to severe malaria in children (English)

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2 August 2017

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12

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2 August 2017

Alex Owusu-Ofori

5

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Daniel Ansong

object named as

Daniel Ansong

4

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Tsiri Agbenyega

1

object named as

Tsiri Agbenyega

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2 August 2017

11

Hartmut Derendorf

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2 August 2017

Tim Planche

2

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2 August 2017

George Bedu-Addo

3

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2 August 2017

Venkatesh A Bhattaram

6

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2 August 2017

Nelamangala V Nagaraja

7

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2 August 2017

Albert L Shroads

8

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2 August 2017

George N Henderson

9

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2 August 2017

Alan D Hutson

10

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2 August 2017

Peter W Stacpoole

13

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2 August 2017

publication date

1 April 2003

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The Journal of Clinical Pharmacology

2 August 2017

published in

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2 August 2017

volume

43

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2 August 2017

issue

4

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2 August 2017

page(s)

386-396

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Pathophysiological and prognostic significance of cerebrospinal-fluid lactate in cerebral malaria

2 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1177%2F0091270003251392

Lactic acidosis and hypoglycaemia in children with severe malaria: pathophysiological and prognostic significance

21 January 2018

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https://api.crossref.org/works/10.1177%2F0091270003251392

The pathophysiologic and prognostic significance of acidosis in severe adult malaria

21 January 2018

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https://api.crossref.org/works/10.1177%2F0091270003251392

Severe falciparum malaria in children: current understanding of pathophysiology and supportive treatment

21 January 2018

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https://api.crossref.org/works/10.1177%2F0091270003251392

Hepatic blood flow and metabolism in severe falciparum malaria: clearance of intravenously administered galactose

21 January 2018

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https://api.crossref.org/works/10.1177%2F0091270003251392

Thiamine deficiency and malaria in adults from southeast Asia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003251392

Plasmodium falciparum: in vitro studies of the pharmacodynamic properties of drugs used for the treatment of severe malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003251392

Treatment of congenital lactic acidosis with dichloroacetate

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003251392

Lactic acidosis and other mitochondrial disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003251392

The pharmacology of dichloroacetate

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003251392

Dichloroacetate for lactic acidosis in severe malaria: a pharmacokinetic and pharmacodynamic assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003251392

The disposition and effects of two doses of dichloroacetate in adults with severe falciparum malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003251392

Glucose and lactate kinetics in children with severe malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003251392

Plasmodium berghei infection: dichloroacetate improves survival in rats with lactic acidosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003251392

Population pharmacokinetics of intramuscular quinine in children with severe malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003251392

Design evaluation for a population pharmacokinetic study using clinical trial simulations: a case study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003251392

Drug treatment effects on disease progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003251392

Dichloroacetate: population pharmacokinetics with a pharmacodynamic sequential link model

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003251392

Pharmacokinetics, metabolism and toxicology of dichloroacetate

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003251392

Disposition and pharmacodynamics of dichloroacetate (DCA) and oxalate following oral DCA doses

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003251392

Xpose--an S-PLUS based population pharmacokinetic/pharmacodynamic model building aid for NONMEM

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003251392

Physiologic indirect response models characterize diverse types of pharmacodynamic effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003251392

Pharmacokinetics and pharmacodynamics of dichloroacetate in patients with cirrhosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003251392

21 January 2018

Identifiers

DOI

10.1177/0091270003251392

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2 August 2017

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