(Q34534913)

2 August 2017

1 reference

title

Gene segment selection in V(D)J recombination: accessibility and beyond (English)

1 reference

2 August 2017

Michael S Krangel

1

1 reference

PubMed ID

12830137

2 August 2017

language of work or name

English

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publication date

1 July 2003

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2 August 2017

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2 August 2017

4

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2 August 2017

7

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2 August 2017

624-630

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The RAG proteins and V(D)J recombination: complexes, ends, and transposition

2 August 2017

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

The mechanism and regulation of chromosomal V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Factors and forces controlling V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Developmentally controlled and tissue-specific expression of unrearranged VH gene segments

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Cell type-specific chromatin structure determines the targeting of V(D)J recombinase activity in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Accessibility of nucleosomal DNA to V(D)J cleavage is modulated by RSS positioning and HMG1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Nucleosome structure completely inhibits in vitro cleavage by the V(D)J recombinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Gene-targeted deletion and replacement mutations of the T-cell receptor beta-chain enhancer: the role of enhancer elements in controlling V(D)J recombination accessibility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Deletion of the mouse T-cell receptor beta gene enhancer blocks alphabeta T-cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Essential roles of the kappa light chain intronic enhancer and 3' enhancer in kappa rearrangement and demethylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Temporal and lineage-specific control of T cell receptor alpha/delta gene rearrangement by T cell receptor alpha and delta enhancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

A developmental switch from TCR delta enhancer to TCR alpha enhancer function during thymocyte maturation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Defect in rearrangement of the most 5' TCR-J alpha following targeted deletion of T early alpha (TEA): implications for TCR alpha locus accessibility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Regulation of V(D)J recombination by transcriptional promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Enhancer control of local accessibility to V(D)J recombinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Enhancer control of V(D)J recombination at the TCRbeta locus: differential effects on DNA cleavage and joining

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Deletion of germline promoter PD beta 1 from the TCR beta locus causes hypermethylation that impairs D beta 1 recombination by multiple mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

The V(D)J recombinational and transcriptional activities of the immunoglobulin heavy-chain intronic enhancer can be mediated through distinct protein-binding sites in a transgenic substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Definition of a T-cell receptor beta gene core enhancer of V(D)J recombination by transgenic mapping.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Evidence that immunoglobulin VH-DJ recombination does not require germ line transcription of the recombining variable gene segment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Regulation of V(D)J recombination: a dominant role for promoter positioning in gene segment accessibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

A role for histone acetylation in the developmental regulation of VDJ recombination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Chromatin remodeling by the T cell receptor (TCR)-beta gene enhancer during early T cell development: Implications for the control of TCR-beta locus recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Histone acetylation determines the developmentally regulated accessibility for T cell receptor gamma gene recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Cutting edge: histone acetylation and recombination at the TCR gamma locus follows IL-7 induction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Stimulation of V(D)J recombination by histone acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Chromatin remodeling directly activates V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Disruption of higher-order folding by core histone acetylation dramatically enhances transcription of nucleosomal arrays by RNA polymerase III

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Cooperation between complexes that regulate chromatin structure and transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

The language of covalent histone modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Translating the Histone Code

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Promoter activation by enhancer-dependent and -independent loading of activator and coactivator complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Lysine-79 of histone H3 is hypomethylated at silenced loci in yeast and mammalian cells: a potential mechanism for position-effect variegation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Kappa chain monoallelic demethylation and the establishment of allelic exclusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

V(D)J recombination is not activated by demethylation of the kappa locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Germ-line transcription and methylation status of the TCR-J alpha locus in its accessible configuration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Regulation of Vbeta germline transcription in RAG-deficient mice by the CD3epsilon-mediated signals: implication of Vbeta transcriptional regulation in TCR beta allelic exclusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

The role of recombination activating gene (RAG) reinduction in thymocyte development in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Regulation of the TCRalpha repertoire by the survival window of CD4(+)CD8(+) thymocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Ordered recruitment of chromatin modifying and general transcription factors to the IFN-beta promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Distribution of acetylated histones resulting from Gal4-VP16 recruitment of SAGA and NuA4 complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Chromatin modification by DNA tracking

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

RNA polymerase II elongation through chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Prospective estimation of recombination signal efficiency and identification of functional cryptic signals in the genome by statistical modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Genetic modulation of T cell receptor gene segment usage during somatic recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

The cleavage efficiency of the human immunoglobulin heavy chain VH elements by the RAG complex: implications for the immune repertoire

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Recombination signal sequences restrict chromosomal V(D)J recombination beyond the 12/23 rule.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Mechanisms that direct ordered assembly of T cell receptor beta locus V, D, and J gene segments

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Extrachromosomal recombination substrates recapitulate beyond 12/23 restricted VDJ recombination in nonlymphoid cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Cutting edge: targeting of V beta to D beta rearrangement by RSSs can be mediated by the V(D)J recombinase in the absence of additional lymphoid-specific factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

The "dispensable" portion of RAG2 is necessary for efficient V-to-DJ rearrangement during B and T cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Dramatically increased rearrangement and peripheral representation of Vbeta14 driven by the 3'Dbeta1 recombination signal sequence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

The basis for the mechanistic bias for deletional over inversional V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

The role of recombination signal sequences in the preferential joining by deletion in DH-JH recombination and in the ordered rearrangement of the IgH locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Ordered assembly of the V(D)J synaptic complex ensures accurate recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Assembly of the RAG1/RAG2 synaptic complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Stepwise activation of the immunoglobulin mu heavy chain gene locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Histone acetylation beyond promoters: long-range acetylation patterns in the chromatin world

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

ChIPs of the beta-globin locus: unraveling gene regulation within an active domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Intergenic transcription and developmental remodeling of chromatin subdomains in the human beta-globin locus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Core promoters: active contributors to combinatorial gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Insulators: many functions, many mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

An enhancer-blocking element between alpha and delta gene segments within the human T cell receptor alpha/delta locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Assessing a role for enhancer-blocking activity in gene regulation within the murine T-cell receptor alpha/delta locus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

The roles of preB and B cell receptors in the stepwise allelic exclusion of mouse IgH and L chain gene loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Allelic exclusion at the TCRbeta locus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Extended duration of DH-JH rearrangement in immunoglobulin heavy chain transgenic mice: implications for regulation of allelic exclusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Transient IL-7/IL-7R signaling provides a mechanism for feedback inhibition of immunoglobulin heavy chain gene rearrangements

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Changes in histone acetylation are associated with differences in accessibility of V(H) gene segments to V-DJ recombination during B-cell ontogeny and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Pax5 is required for recombination of transcribed, acetylated, 5' IgH V gene segments

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Differential accessibility at the kappa chain locus plays a role in allelic exclusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Biallelic germline transcription at the kappa immunoglobulin locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Replication timing and transcriptional control: beyond cause and effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

21 January 2018

Replicating by the clock

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Establishment of transcriptional competence in early and late S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Replication and subnuclear location dynamics of the immunoglobulin heavy-chain locus in B-lineage cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Asynchronous replication and allelic exclusion in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

Function of the TCR alpha enhancer in alphabeta and gammadelta T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

7 January 2021

Control of V(D)J recombinational accessibility of the D beta 1 gene segment at the TCR beta locus by a germline promoter

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

7 January 2021

Histone acetylation and hSWI/SNF remodeling act in concert to stimulate V(D)J cleavage of nucleosomal DNA

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

7 January 2021

Gcn4 activator targets Gcn5 histone acetyltransferase to specific promoters independently of transcription

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

7 January 2021

A change in the structure of Vbeta chromatin associated with TCR beta allelic exclusion

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

7 January 2021

Developmentally programmed rearrangement of T cell receptor Vgamma genes is controlled by sequences immediately upstream of the Vgamma genes

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

7 January 2021

The IL-7 receptor controls the accessibility of the TCRgamma locus by Stat5 and histone acetylation

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

7 January 2021

Coordination of the random asynchronous replication of autosomal loci

1 reference

https://api.crossref.org/works/10.1038%2FNI0703-624

7 January 2021

Identifiers

DOI

10.1038/NI0703-624

1 reference

2 August 2017

1 reference

PubMed ID

12830137