(Q51840167)

13 April 2018

title

Extrachromosomal recombination substrates recapitulate beyond 12/23 restricted VDJ recombination in nonlymphoid cells. (English)

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13 April 2018

author name string

David Jung

1

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13 April 2018

Craig H Bassing

2

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13 April 2018

Sebastian D Fugmann

3

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13 April 2018

Hwei-Ling Cheng

4

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13 April 2018

David G Schatz

5

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13 April 2018

Frederick W Alt

6

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13 April 2018

language of work or name

English

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publication date

1 January 2003

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13 April 2018

published in

Immunity

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13 April 2018

volume

18

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13 April 2018

issue

1

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13 April 2018

page(s)

65-74

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13 April 2018

Recombination signal sequences restrict chromosomal V(D)J recombination beyond the 12/23 rule.

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Rearrangement of T-cell receptor beta-chain genes during T-cell development

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Diversity and structure of human T-cell receptor beta-chain variable region genes

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Analysis of regions of RAG-2 important for V(D)J recombination

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An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH.

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Initiation of V(D)J recombination in vitro obeying the 12/23 rule

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7 January 2021

Asymmetric processing of coding ends and the effect of coding end nucleotide composition on V(D)J recombination

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Mouse RSS spacer sequences affect the rate of V(D)J recombination

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The RAG proteins and V(D)J recombination: complexes, ends, and transposition

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Identification of two catalytic residues in RAG1 that define a single active site within the RAG1/RAG2 protein complex.

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7 January 2021

The basis for the mechanistic bias for deletional over inversional V(D)J recombination

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7 January 2021

Coding end sequence can markedly affect the initiation of V(D)J recombination

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7 January 2021

Extrachromosomal DNA substrates in pre-B cells undergo inversion or deletion at immunoglobulin V-(D)-J joining signals

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7 January 2021

V(D)J recombination: a functional definition of the joining signals

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7 January 2021

Factors and forces controlling V(D)J recombination

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7 January 2021

Assembly of a 12/23 paired signal complex: a critical control point in V(D)J recombination

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7 January 2021

Ordered assembly of the V(D)J synaptic complex ensures accurate recombination

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7 January 2021

Functional analysis of coordinated cleavage in V(D)J recombination

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7 January 2021

Sequences and diversity of human T cell receptor beta chain variable region genes

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The defect in murine severe combined immune deficiency: joining of signal sequences but not coding segments in V(D)J recombination

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Genetic modulation of T cell receptor gene segment usage during somatic recombination

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7 January 2021

Sequences of five potential recombination sites encoded close to an immunoglobulin kappa constant region gene

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7 January 2021

A basic motif in the N-terminal region of RAG1 enhances V(D)J recombination activity

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7 January 2021

Sequence of the spacer in the recombination signal sequence affects V(D)J rearrangement frequency and correlates with nonrandom Vkappa usage in vivo

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7 January 2021

The role of recombination signal sequences in the preferential joining by deletion in DH-JH recombination and in the ordered rearrangement of the IgH locus

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7 January 2021

Level of human TCRBV3S1 (V beta 3) expression correlates with allelic polymorphism in the spacer region of the recombination signal sequence

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7 January 2021

Complementation of V(D)J recombination deficiency in RAG-1(-/-) B cells reveals a requirement for novel elements in the N-terminus of RAG-1.

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7 January 2021

Expression and V(D)J recombination activity of mutated RAG-1 proteins

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7 January 2021

Definition of a core region of RAG-2 that is functional in V(D)J recombination

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7 January 2021

Sequences at the somatic recombination sites of immunoglobulin light-chain genes

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7 January 2021

V(D)J recombination: modulation of RAG1 and RAG2 cleavage activity on 12/23 substrates by whole cell extract and DNA-bending proteins

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7 January 2021

Increased accumulation of hybrid V(D)J joins in cells expressing truncated versus full-length RAGs.

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7 January 2021

V(D)J recombination: signal and coding joint resolution are uncoupled and depend on parallel synapsis of the sites

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7 January 2021

Dispensable sequence motifs in the RAG-1 and RAG-2 genes for plasmid V(D)J recombination

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7 January 2021

Mechanisms that direct ordered assembly of T cell receptor beta locus V, D, and J gene segments

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7 January 2021

Roles of the "dispensable" portions of RAG-1 and RAG-2 in V(D)J recombination

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7 January 2021

Impairment of V(D)J recombination in double-strand break repair mutants

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7 January 2021

HMG1 and 2, and related 'architectural' DNA-binding proteins

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7 January 2021

Restrictions limiting the generation of DNA double strand breaks during chromosomal V(D)J recombination

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7 January 2021

Somatic generation of antibody diversity

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7 January 2021

In transgenic mice the introduced functional T cell receptor beta gene prevents expression of endogenous beta genes

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7 January 2021

The RAG1 and RAG2 proteins establish the 12/23 rule in V(D)J recombination

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7 January 2021

Stimulation of V(D)J cleavage by high mobility group proteins

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7 January 2021

The RAG-HMG1 complex enforces the 12/23 rule of V(D)J recombination specifically at the double-hairpin formation step

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7 January 2021

Dramatically increased rearrangement and peripheral representation of Vbeta14 driven by the 3'Dbeta1 recombination signal sequence.

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7 January 2021

The cleavage efficiency of the human immunoglobulin heavy chain VH elements by the RAG complex: implications for the immune repertoire

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7 January 2021

10.1016/S1074-7613(02)00507-1

Identifiers

DOI

1 reference

13 April 2018

1 reference

13 April 2018