(Q34543130)

2 August 2017

title

Using tetracyclines to treat osteoporotic/osteopenic bone loss: from the basic science laboratory to the clinic (English)

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2 August 2017

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2

Lorne M Golub

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2 August 2017

Jeffrey B Payne

1

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2 August 2017

publication date

16 October 2010

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2 August 2017

published in

Pharmacological Research

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2 August 2017

volume

63

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2 August 2017

issue

2

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2 August 2017

page(s)

121-129

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Periodontitis: a future risk of acute coronary syndrome? A follow-up study over 3 years

2 August 2017

cites work

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Doxycycline delays aneurysm rupture in a mouse model of Marfan syndrome

7 July 2018

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7 July 2018

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7 July 2018

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Subantimicrobial dose doxycycline effects on osteopenic bone loss: microbiologic results

7 July 2018

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7 July 2018

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B and T lymphocytes are the primary sources of RANKL in the bone resorptive lesion of periodontal disease

7 July 2018

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Osteoclast differentiation and activation

7 July 2018

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Effects of Subantimicrobial-Dose Doxycycline in the Treatment of Moderate Acne

7 July 2018

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Phase I clinical trial of oral COL-3, a matrix metalloproteinase inhibitor, in patients with refractory metastatic cancer

7 July 2018

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A role for the anti-inflammatory properties of tetracyclines in the prevention of acute lung injury

7 July 2018

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The lipophilicity, pharmacokinetics, and cellular uptake of different chemically-modified tetracyclines (CMTs).

7 July 2018

1 reference

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7 July 2018

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C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women

7 July 2018

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Non-antimicrobial and antimicrobial tetracyclines inhibit IL-6 expression in murine osteoblasts

7 July 2018

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Potential application of low-dose doxycycline to treat periodontitis in post-menopausal women

7 July 2018

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The "cyclic" regimen of low-dose doxycycline for adult periodontitis: a preliminary study

7 July 2018

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Tetracyclines Inhibit Connective Tissue Breakdown: New Therapeutic Implications for an Old Family of Drugs

7 July 2018

1 reference

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Host modulation with tetracyclines and their chemically modified analogues

7 July 2018

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Is the excessive inhibition of matrix metalloproteinases (MMPs) by potent synthetic MMP inhibitors (MMPIs) desirable in periodontitis and other inflammatory diseases? That is: 'Leaky' MMPIs vs excessively efficient drugs

7 July 2018

1 reference

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Clinical and biochemical results of the metalloproteinase inhibition with subantimicrobial doses of doxycycline to prevent acute coronary syndromes (MIDAS) pilot trial.

27 October 2018

1 reference

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Chemically modified tetracyclines selectively inhibit IL-6 expression in osteoblasts by decreasing mRNA stability

27 October 2018

1 reference

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Inhibition of matrix metalloproteinase-mediated periodontal bone loss in rats: a comparison of 6 chemically modified tetracyclines

27 October 2018

1 reference

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Inhibition of cell proliferation, invasion, tumor growth and metastasis by an oral non-antimicrobial tetracycline analog (COL-3) in a metastatic prostate cancer model

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031719

Treatment with subantimicrobial dose doxycycline improves the efficacy of scaling and root planing in patients with adult periodontitis.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031719

A chemically modified tetracycline inhibits streptozotocin-induced diabetic depression of skin collagen synthesis and steady-state type I procollagen mRNA.

27 October 2018

1 reference

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A chemically modified nonantimicrobial tetracycline (CMT-8) inhibits gingival matrix metalloproteinases, periodontal breakdown, and extra-oral bone loss in ovariectomized rats

27 October 2018

1 reference

12 December 2020

The relationship between bone mineral density and periodontitis in postmenopausal women

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12 December 2020

Patterns of progression and regression of advanced destructive periodontal disease

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12 December 2020

Minocycline reduces gingival collagenolytic activity during diabetes. Preliminary observations and a proposed new mechanism of action

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12 December 2020

Tetracyclines inhibit parathyroid hormone-induced bone resorption in organ culture

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12 December 2020

Tetracycline administration increases collagen synthesis in osteoblasts of streptozotocin-induced diabetic rats: a quantitative autoradiographic study

1 reference

12 December 2020

A non-antimicrobial tetracycline inhibits gingival matrix metalloproteinases and bone loss in Porphyromonas gingivalis-induced periodontitis in rats

1 reference

12 December 2020

Minocycline prevents the decrease in bone mineral density and trabecular bone in ovariectomized aged rats

1 reference

12 December 2020

alpha 1-Proteinase inhibitor in gingival crevicular fluid of humans with adult periodontitis: serpinolytic inhibition by doxycycline

1 reference

12 December 2020

Tetracycline prevents cancellous bone loss and maintains near-normal rates of bone formation in streptozotocin diabetic rats

1 reference

12 December 2020

A matrix metalloproteinase inhibitor reduces bone-type collagen degradation fragments and specific collagenases in gingival crevicular fluid during adult periodontitis

1 reference

12 December 2020

Tetracyclines inhibit connective tissue breakdown by multiple non-antimicrobial mechanisms

1 reference

12 December 2020

Influence of estrogen and osteopenia/osteoporosis on clinical periodontitis in postmenopausal women

1 reference

12 December 2020

Longitudinal alveolar bone loss in postmenopausal osteoporotic/osteopenic women

1 reference

12 December 2020

Efficacy of Periodontal Disease and Tooth Loss to Screen for Low Bone Mineral Density in Japanese Women

1 reference

12 December 2020

A randomized, double-blind, placebo-controlled trial of the combined effect of doxycycline hyclate 20-mg tablets and metronidazole 0.75% topical lotion in the treatment of rosacea

1 reference

12 December 2020

Treatment of early seropositive rheumatoid arthritis: doxycycline plus methotrexate versus methotrexate alone

1 reference

12 December 2020

Randomized phase II trial of matrix metalloproteinase inhibitor COL-3 in AIDS-related Kaposi's sarcoma: an AIDS Malignancy Consortium Study

1 reference

12 December 2020

Relationship between serum hsCRP concentration and biochemical bone turnover markers in healthy pre- and postmenopausal women

1 reference

12 December 2020

Subantimicrobial-dose doxycycline modulates gingival crevicular fluid biomarkers of periodontitis in postmenopausal osteopenic women

1 reference

12 December 2020

Doxycycline 40 mg capsules (30 mg immediate-release/10 mg delayed-release beads): anti-inflammatory dose in rosacea

1 reference

12 December 2020

Doxycycline [corrected] inhibits mononuclear cell-mediated connective tissue breakdown

1 reference

12 December 2020

Effects of chemically modified tetracycline, CMT-8, on bone loss and osteoclast structure and function in osteoporotic states

1 reference

12 December 2020

10.1016/J.PHRS.2010.10.006

Identifiers

DOI

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2 August 2017

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2 August 2017

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