(Q34549474)

3 August 2017

title

Downregulation of NCC and NKCC2 cotransporters by kidney-specific WNK1 revealed by gene disruption and transgenic mouse models (English)

1 reference

3 August 2017

Zhen Liu

1

1 reference

3 August 2017

Jian Xie

2

1 reference

3 August 2017

Tao Wu

3

1 reference

3 August 2017

Thao Truong

4

1 reference

3 August 2017

Richard J Auchus

5

1 reference

3 August 2017

Chou-Long Huang

6

1 reference

3 August 2017

publication date

2 December 2010

1 reference

3 August 2017

published in

Human Molecular Genetics

1 reference

3 August 2017

volume

20

1 reference

3 August 2017

issue

5

1 reference

3 August 2017

page(s)

855-866

1 reference

On the substrate recognition and negative regulation of SPAK, a kinase modulating Na+-K+-2Cl- cotransport activity

3 August 2017

cites work

1 reference

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Vasopressin induces phosphorylation of the thiazide-sensitive sodium chloride cotransporter in the distal convoluted tubule

7 July 2018

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Role of the WNK-activated SPAK kinase in regulating blood pressure

7 July 2018

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Regulation of ROMK channel and K+ homeostasis by kidney-specific WNK1 kinase

7 July 2018

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Aldosterone, but not increased Na+ influx or NF-kappaB activation, increases kidney-specific WNK1 gene expression in renal collecting duct cells

7 July 2018

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The regulation of salt transport and blood pressure by the WNK-SPAK/OSR1 signalling pathway

7 July 2018

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Activation of the thiazide-sensitive Na+-Cl- cotransporter by the WNK-regulated kinases SPAK and OSR1

7 July 2018

1 reference

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SPAK and OSR1: STE20 kinases involved in the regulation of ion homoeostasis and volume control in mammalian cells

7 July 2018

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Intersectin links WNK kinases to endocytosis of ROMK1

7 July 2018

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The Na+:Cl- cotransporter is activated and phosphorylated at the amino-terminal domain upon intracellular chloride depletion

7 July 2018

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WNK1 and OSR1 regulate the Na+, K+, 2Cl- cotransporter in HeLa cells

7 July 2018

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Antagonistic regulation of ROMK by long and kidney-specific WNK1 isoforms

7 July 2018

1 reference

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WNK1 regulates phosphorylation of cation-chloride-coupled cotransporters via the STE20-related kinases, SPAK and OSR1.

7 July 2018

1 reference

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Dominant-negative regulation of WNK1 by its kidney-specific kinase-defective isoform

7 July 2018

1 reference

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The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases

7 July 2018

1 reference

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WNK1 activates SGK1 to regulate the epithelial sodium channel.

7 July 2018

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Mechanisms of WNK1 and WNK4 interaction in the regulation of thiazide-sensitive NaCl cotransport

7 July 2018

1 reference

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The kidney-specific WNK1 isoform is induced by aldosterone and stimulates epithelial sodium channel-mediated Na+ transport

7 July 2018

1 reference

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Disease-causing mutant WNK4 increases paracellular chloride permeability and phosphorylates claudins

7 July 2018

1 reference

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Multiple promoters in the WNK1 gene: one controls expression of a kidney-specific kinase-defective isoform

7 July 2018

1 reference

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WNK4 regulates the balance between renal NaCl reabsorption and K+ secretion

7 July 2018

1 reference

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WNK kinases regulate thiazide-sensitive Na-Cl cotransport

7 July 2018

1 reference

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Molecular pathogenesis of inherited hypertension with hyperkalemia: the Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4

7 July 2018

1 reference

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WNK kinases, a novel protein kinase subfamily in multi-cellular organisms

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033178

Human hypertension caused by mutations in WNK kinases

7 July 2018

1 reference

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The Na-K-Cl cotransporter of secretory epithelia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033178

WNK1, a novel mammalian serine/threonine protein kinase lacking the catalytic lysine in subdomain II

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033178

Expression of the mouse Na-K-2Cl cotransporter, mBSC2, in the terminal inner medullary collecting duct, the glomerular and extraglomerular mesangium, and the glomerular afferent arteriole

7 July 2018

1 reference

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Molecular cloning and chromosome localization of a putative basolateral Na(+)-K(+)-2Cl- cotransporter from mouse inner medullary collecting duct (mIMCD-3) cells

7 July 2018

1 reference

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Primary structure, functional expression, and chromosomal localization of the bumetanide-sensitive Na-K-Cl cotransporter in human colon

7 July 2018

1 reference

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WNK1, a Gene within a Novel Blood Pressure Control Pathway, Tissue-Specifically Generates Radically Different Isoforms with and without a Kinase Domain

7 July 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ525

Dietary electrolyte-driven responses in the renal WNK kinase pathway in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ525

Targeted disruption of the Wnk4 gene decreases phosphorylation of Na-Cl cotransporter, increases Na excretion and lowers blood pressure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ525

Short-term stimulation of the thiazide-sensitive Na+-Cl- cotransporter by vasopressin involves phosphorylation and membrane translocation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ525

Deletion of WNK1 first intron results in misregulation of both isoforms in renal and extrarenal tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ525

Polarized distribution of key membrane transport proteins in the rat submandibular gland

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21131289

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Simultaneous determination of 12 steroids by isotope dilution liquid chromatography-photospray ionization tandem mass spectrometry

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21131289

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Molecular pathogenesis of pseudohypoaldosteronism type II: generation and analysis of a Wnk4(D561A/+) knockin mouse model

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21131289

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/HMG/DDQ525

1 reference

3 August 2017

1 reference

3 August 2017

1 reference