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ICP27 selectively regulates the cytoplasmic localization of a subset of viral transcripts in herpes simplex virus type 1-infected cells
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PMC publication ID
303382
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21 December 2019
title
ICP27 selectively regulates the cytoplasmic localization of a subset of viral transcripts in herpes simplex virus type 1-infected cells
(English)
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PMC publication ID
303382
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21 December 2019
author
Angela Pearson
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1
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303382
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21 December 2019
author name string
David M Knipe
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2
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303382
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21 December 2019
Donald M Coen
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3
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303382
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21 December 2019
language of work or name
English
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publication date
1 January 2004
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21 December 2019
published in
Journal of Virology
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303382
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21 December 2019
volume
78
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Europe PubMed Central
PMC publication ID
303382
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21 December 2019
issue
1
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Europe PubMed Central
PMC publication ID
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21 December 2019
page(s)
23-32
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21 December 2019
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Herpes simplex virus IE63 (ICP27) protein interacts with spliceosome-associated protein 145 and inhibits splicing prior to the first catalytic step
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ICP27 mediates HSV RNA export by shuttling through a leucine-rich nuclear export signal and binding viral intronless RNAs through an RGG motif
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The acidic amino-terminal region of herpes simplex virus type 1 alpha protein ICP27 is required for an essential lytic function.
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7 July 2018
The herpes simplex virus regulatory protein ICP27 contributes to the decrease in cellular mRNA levels during infection
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7 July 2018
Herpes simplex virus inhibits host cell splicing, and regulatory protein ICP27 is required for this effect
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The herpes simplex virus UL20 protein compensates for the differential disruption of exocytosis of virions and viral membrane glycoproteins associated with fragmentation of the Golgi apparatus
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Thymidine Kinase Deletion Mutants of Herpes Simplex Virus Type 1
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Cloning of herpes simplex virus type 1 sequences representing the whole genome
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Transcriptional and genetic analyses of the herpes simplex virus type 1 genome: coordinates 0.29 to 0.45
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7 July 2018
Nucleotide sequence and predicted amino acid sequence of a protein encoded in a small herpes simplex virus DNA fragment capable of trans-inducing alpha genes
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7 July 2018
Sensitivity of arabinosyladenine-resistant mutants of herpes simplex virus to other antiviral drugs and mapping of drug hypersensitivity mutations to the DNA polymerase locus
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7 July 2018
The herpes simplex virus type 1 alpha protein ICP27 can act as a trans-repressor or a trans-activator in combination with ICP4 and ICP0.
1 reference
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7 July 2018
The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA
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7 July 2018
Herpes simplex virus alpha protein ICP27 can inhibit or augment viral gene transactivation
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PubMed Central
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7 July 2018
A conserved open reading frame that overlaps the herpes simplex virus thymidine kinase gene is important for viral growth in cell culture
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7 July 2018
Herpes simplex virus type 1 ICP27 deletion mutants exhibit altered patterns of transcription and are DNA deficient
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stated in
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7 July 2018
Genetic evidence for two distinct transactivation functions of the herpes simplex virus alpha protein ICP27.
1 reference
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7 July 2018
Phenotypic and genotypic characterization of locus Syn 5 in herpes simplex virus 1
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7 July 2018
Herpes simplex virus IE63 acts at the posttranscriptional level to stimulate viral mRNA 3' processing
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7 July 2018
Temperature-sensitive mutants of herpes simplex virus type 1 defective in lysis but not in transformation
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7 July 2018
SR splicing factors serve as adapter proteins for TAP-dependent mRNA export
1 reference
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27 October 2018
Identification and characterization of the UL24 gene product of herpes simplex virus type 2.
1 reference
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27 October 2018
Identifiers
DOI
10.1128/JVI.78.1.23-32.2004
1 reference
stated in
Europe PubMed Central
PMC publication ID
303382
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14671084%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 December 2019
PMC publication ID
303382
1 reference
stated in
Europe PubMed Central
PMC publication ID
303382
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14671084%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 December 2019
PubMed publication ID
14671084
1 reference
stated in
Europe PubMed Central
PMC publication ID
303382
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14671084%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 December 2019
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