(Q34561698)

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Epidermal growth factor receptor signaling synergizes with Hedgehog/GLI in oncogenic transformation via activation of the MEK/ERK/JUN pathway

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Epidermal growth factor receptor signaling synergizes with Hedgehog/GLI in oncogenic transformation via activation of the MEK/ERK/JUN pathway (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

object named as

Maria Kasper

5

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object named as

Maria Sibilia

10

0 references

object named as

Fritz Aberger

11

0 references

Richard Moriggl

object named as

Richard Moriggl

9

0 references

author name string

Harald Schnidar

1

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Markus Eberl

2

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Stefan Klingler

3

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Doris Mangelberger

4

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Cornelia Hauser-Kronberger

6

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Gerhard Regl

7

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Renate Kroismayr

8

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Europe PubMed Central

PubMed publication ID

3 August 2017

language of work or name

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publication date

3 February 2009

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Cancer Research

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Europe PubMed Central

PubMed publication ID

3 August 2017

69

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

1284-1292

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

The different functions of Stat5 and chromatin alteration through Stat5 proteins

1 reference

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7 July 2018

Application of active and kinase-deficient kinome collection for identification of kinases regulating hedgehog signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035872

7 July 2018

GLI1 repression of ERK activity correlates with colony formation and impaired migration in human epidermal keratinocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035872

7 July 2018

Efficient manipulation of Hedgehog/GLI signaling using retroviral expression systems.

1 reference

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7 July 2018

The epidermal growth factor receptor: from development to tumorigenesis

1 reference

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The Gli code: an information nexus regulating cell fate, stemness and cancer.

1 reference

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Non-canonical activation of GLI transcription factors: implications for targeted anti-cancer therapy

1 reference

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Differential ErbB1 signaling in squamous cell versus basal cell carcinoma of the skin

1 reference

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Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists

1 reference

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7 July 2018

Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways.

1 reference

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Fibroblast growth factor blocks Sonic hedgehog signaling in neuronal precursors and tumor cells.

1 reference

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Regulation of Hh/Gli signaling by dual ubiquitin pathways

1 reference

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7 July 2018

Long-term establishment, characterization and manipulation of cell lines from mouse basal cell carcinoma tumors

1 reference

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7 July 2018

Hedgehog signal transduction: signal integration and cross talk in development and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035872

7 July 2018

Selective modulation of Hedgehog/GLI target gene expression by epidermal growth factor signaling in human keratinocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035872

7 July 2018

Phosphoinositide 3-kinase and Akt are essential for Sonic Hedgehog signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035872

7 July 2018

GLI transcription factors: mediators of oncogenic Hedgehog signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035872

7 July 2018

Oncogenic transformation by inhibitor-sensitive and -resistant EGFR mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035872

7 July 2018

ERBB receptors and cancer: the complexity of targeted inhibitors

1 reference

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7 July 2018

Sonic hedgehog induces epidermal growth factor dependent matrix infiltration in HaCaT keratinocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035872

7 July 2018

Sonic hedgehog controls stem cell behavior in the postnatal and adult brain

1 reference

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Tissue repair and stem cell renewal in carcinogenesis

1 reference

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7 July 2018

MIM/BEG4, a Sonic hedgehog-responsive gene that potentiates Gli-dependent transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035872

7 July 2018

Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035872

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EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035872

7 July 2018

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035872

7 July 2018

The zinc-finger transcription factor GLI2 antagonizes contact inhibition and differentiation of human epidermal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035872

7 July 2018

AP-1: a double-edged sword in tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035872

7 July 2018

c-Jun regulates eyelid closure and skin tumor development through EGFR signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035872

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A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference

1 reference

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Sonic hedgehog in normal and neoplastic proliferation: insight gained from human tumors and animal models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035872

7 July 2018

Human GLI2 and GLI1 are part of a positive feedback mechanism in Basal Cell Carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035872

7 July 2018

Untangling the ErbB signalling network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035872

7 July 2018

Cell signaling by receptor tyrosine kinases

1 reference

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The EGF receptor provides an essential survival signal for SOS-dependent skin tumor development

1 reference

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7 July 2018

Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035872

7 July 2018

Epidermal growth factor receptors: critical mediators of multiple receptor pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035872

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Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway

1 reference

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Differential regulation of c-Jun by ERK and JNK during PC12 cell differentiation.

1 reference

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AP-1 factors play an important role in transformation induced by the v-rel oncogene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035872

7 July 2018

Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035872

7 July 2018

The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035872

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Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035872

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Phosphorylation of c-jun mediated by MAP kinases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035872

7 July 2018

The zinc finger protein GLI transforms primary cells in cooperation with adenovirus E1A

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035872

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Patching the gaps in Hedgehog signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035872

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Cytotoxic effects induced by a combination of cyclopamine and gefitinib, the selective hedgehog and epidermal growth factor receptor signaling inhibitors, in prostate cancer cells

1 reference

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Hedgehog-GLI signaling regulates the behavior of cells with stem cell properties in the developing neocortex.

1 reference

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Targeting the Hedgehog pathway in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19190345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combined targeting of epidermal growth factor receptor and hedgehog signaling by gefitinib and cyclopamine cooperatively improves the cytotoxic effects of docetaxel on metastatic prostate cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19190345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/0008-5472.CAN-08-2331

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

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