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Telomerase reverse transcriptase synergizes with calorie restriction to increase health span and extend mouse longevity
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scholarly article
1 reference
stated in
Q5412157
PubMed ID
23349740
retrieved
3 August 2017
title
Telomerase reverse transcriptase synergizes with calorie restriction to increase health span and extend mouse longevity
(English)
1 reference
stated in
Q5412157
PubMed ID
23349740
retrieved
3 August 2017
main subject
health span
1 reference
based on heuristic
inferred from title
calorie restriction
1 reference
based on heuristic
inferred from title
author
Bruno M Bernardes de Jesus
object named as
Bruno Bernardes de Jesus
series ordinal
2
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Miguel Foronda
object named as
Miguel Foronda
series ordinal
3
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Maria A Blasco
object named as
Maria A Blasco
series ordinal
5
0 references
author name string
Elsa Vera
series ordinal
1
1 reference
stated in
Q5412157
PubMed ID
23349740
retrieved
3 August 2017
Juana M Flores
series ordinal
4
1 reference
stated in
Q5412157
PubMed ID
23349740
retrieved
3 August 2017
language of work or name
English
0 references
publication date
22 January 2013
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stated in
Q5412157
PubMed ID
23349740
retrieved
3 August 2017
published in
PLOS One
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stated in
Q5412157
PubMed ID
23349740
retrieved
3 August 2017
volume
8
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stated in
Q5412157
PubMed ID
23349740
retrieved
3 August 2017
page(s)
e53760
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stated in
Q5412157
PubMed ID
23349740
retrieved
3 August 2017
issue
1
1 reference
stated in
Q5412157
PubMed ID
23349740
retrieved
3 August 2017
copyright license
Creative Commons Attribution 4.0 International
start time
22 January 2013
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stated in
April 2022 Public Data File from Crossref
copyright status
copyrighted
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cites work
Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study
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PubMed Central
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Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer
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7 July 2018
Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila
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7 July 2018
CKIα ablation highlights a critical role for p53 in invasiveness control
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7 July 2018
Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice
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7 July 2018
Extending healthy life span--from yeast to humans
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7 July 2018
Calorie restriction and cancer prevention: metabolic and molecular mechanisms
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7 July 2018
Telomere diseases
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7 July 2018
Genetic variation in the murine lifespan response to dietary restriction: from life extension to life shortening
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
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7 July 2018
Caloric restriction: from soup to nuts
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
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7 July 2018
Caloric restriction, SIRT1 and longevity
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
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7 July 2018
Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
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7 July 2018
Caloric restriction delays disease onset and mortality in rhesus monkeys
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
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7 July 2018
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
1 reference
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PubMed Central
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7 July 2018
Caloric restriction and aging: studies in mice and monkeys
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7 July 2018
Telomerase reverse transcriptase delays aging in cancer-resistant mice
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
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7 July 2018
Caloric restriction decreases cortical bone mass but spares trabecular bone in the mouse skeleton: implications for the regulation of bone mass by body weight.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
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7 July 2018
Evaluation of glucose homeostasis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
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7 July 2018
Telomere length, stem cells and aging
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
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7 July 2018
Cellular senescence in cancer and aging
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
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7 July 2018
Telomerase mutations in families with idiopathic pulmonary fibrosis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
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7 July 2018
High-throughput telomere length quantification by FISH and its application to human population studies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
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7 July 2018
Aging, adiposity, and calorie restriction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
retrieved
7 July 2018
Telomerase regulation and stem cell behaviour
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
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7 July 2018
Shelterin: the protein complex that shapes and safeguards human telomeres
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stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
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7 July 2018
Telomeres and human disease: ageing, cancer and beyond
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
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7 July 2018
Minireview: role of the growth hormone/insulin-like growth factor system in mammalian aging
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PubMed Central
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7 July 2018
Calorie restriction, SIRT1 and metabolism: understanding longevity
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PubMed Central
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7 July 2018
Calorie restriction--the SIR2 connection
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PubMed Central
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7 July 2018
The plasticity of aging: insights from long-lived mutants
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PubMed Central
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7 July 2018
Antagonistic effects of telomerase on cancer and aging in K5-mTert transgenic mice.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
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7 July 2018
Accelerated telomere shortening in response to life stress
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
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7 July 2018
Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
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7 July 2018
Temporal linkage between the phenotypic and genomic responses to caloric restriction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
retrieved
7 July 2018
A DNA damage checkpoint response in telomere-initiated senescence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
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7 July 2018
Bone development and age-related bone loss in male C57BL/6J mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
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7 July 2018
How does calorie restriction work?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
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7 July 2018
Oxidative stress shortens telomeres
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
retrieved
7 July 2018
New ways not to make ends meet: telomerase, DNA damage proteins and heterochromatin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
retrieved
7 July 2018
Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
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7 July 2018
Telomere length abnormalities in mammalian radiosensitive cells
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
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7 July 2018
Oxidants, oxidative stress and the biology of ageing
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
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7 July 2018
A telomerase component is defective in the human disease dyskeratosis congenita
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
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7 July 2018
Controlling caloric consumption: protocols for rodents and rhesus monkeys
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
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7 July 2018
Disease states associated with telomerase deficiency appear earlier in mice with short telomeres
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
retrieved
7 July 2018
Telomeres in the mouse have large inter-chromosomal variations in the number of T2AG3 repeats
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
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7 July 2018
Telomerase activity in normal and malignant hematopoietic cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
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7 July 2018
The retardation of aging in mice by dietary restriction: longevity, cancer, immunity and lifetime energy intake
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
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7 July 2018
Assessing the predictive validity of psychomotor tests as measures of biological age in mice.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
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7 July 2018
The effect of retarded growth upon the length of life span and upon the ultimate body size. 1935
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
retrieved
7 July 2018
Telomeres shorten during ageing of human fibroblasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551964
retrieved
7 July 2018
The impact of acute caloric restriction on the metabolic phenotype in male C57BL/6 and DBA/2 mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053760
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21 January 2018
The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053760
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21 January 2018
Effects of long-term caloric restriction on glucose homeostasis and on the first steps of the insulin signaling system in skeletal muscle of normal and Ames dwarf (Prop1df/Prop1df) mice
1 reference
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Crossref
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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053760
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21 January 2018
Cellular senescence in aging primates.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053760
retrieved
21 January 2018
Growth curves and survival characteristics of the animals used in the Biomarkers of Aging Program
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23349740
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The Rate of Increase of Short Telomeres Predicts Longevity in Mammals
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23349740
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Delayed kinetics of DNA double-strand break processing in normal and pathological aging
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23349740
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
DNA damage response and cellular senescence in tissues of aging mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23349740
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Dietary restriction reduces insulin-like growth factor I levels, which modulates apoptosis, cell proliferation, and tumor progression in p53-deficient mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23349740
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Dietary restriction in mice beginning at 1 year of age: effect on life-span and spontaneous cancer incidence
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23349740
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1371/JOURNAL.PONE.0053760
1 reference
stated in
Q5412157
PubMed ID
23349740
retrieved
3 August 2017
ADS bibcode
2013PLoSO...853760V
0 references
PMCID
3551964
1 reference
stated in
Q5412157
PubMed ID
23349740
retrieved
3 August 2017
PubMed ID
23349740
1 reference
stated in
Q5412157
PubMed ID
23349740
retrieved
3 August 2017
ResearchGate publication ID
235372095
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