(Q34581220)

3 August 2017

title

Cerebral small vessel disease-related protease HtrA1 processes latent TGF-β binding protein 1 and facilitates TGF-β signaling (English)

1 reference

3 August 2017

Nathalie Beaufort

1

0 references

Michael Ehrmann

object named as

Michael Ehrmann

5

0 references

Martin Dichgans

10

object named as

Martin Dichgans

1 reference

3 August 2017

6

Robert Huber

1 reference

3 August 2017

Eva Scharrer

2

1 reference

3 August 2017

Elisabeth Kremmer

3

1 reference

3 August 2017

Vanda Lux

4

1 reference

3 August 2017

Henry Houlden

7

1 reference

3 August 2017

David Werring

8

1 reference

3 August 2017

Christof Haffner

9

1 reference

3 August 2017

language of work or name

English

0 references

publication date

4 November 2014

1 reference

Proceedings of the National Academy of Sciences of the United States of America

3 August 2017

published in

1 reference

3 August 2017

volume

111

1 reference

3 August 2017

issue

46

1 reference

3 August 2017

page(s)

16496-16501

1 reference

Sequestration of latent TGF-β binding protein 1 into CADASIL-related Notch3-ECD deposits

3 August 2017

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1 reference

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7 July 2018

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Serine protease HTRA1 antagonizes transforming growth factor-β signaling by cleaving its receptors and loss of HTRA1 in vivo enhances bone formation

7 July 2018

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Downregulation of serine protease HTRA1 is associated with poor survival in breast cancer

7 July 2018

1 reference

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7 July 2018

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Matrix control of transforming growth factor-β function

7 July 2018

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7 July 2018

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Matrix-dependent perturbation of TGFβ signaling and disease

7 July 2018

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Human high temperature requirement serine protease A1 (HTRA1) degrades tau protein aggregates

7 July 2018

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Specificity of latent TGF-β binding protein (LTBP) incorporation into matrix: role of fibrillins and fibronectin

7 July 2018

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LTBPs, more than just an escort service.

7 July 2018

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Increased expression of multifunctional serine protease, HTRA1, in retinal pigment epithelium induces polypoidal choroidal vasculopathy in mice

7 July 2018

1 reference

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Overexpression of HTRA1 leads to ultrastructural changes in the elastic layer of Bruch's membrane via cleavage of extracellular matrix components

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246310

HTRA proteases: regulated proteolysis in protein quality control

7 July 2018

1 reference

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Cerebral small-vessel disease protein HTRA1 controls the amount of TGF-β1 via cleavage of proTGF-β1.

7 July 2018

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Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL): from discovery to gene identification

7 July 2018

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Signaling by members of the TGF-beta family in vascular morphogenesis and disease

7 July 2018

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Identification of novel substrates for the serine protease HTRA1 in the human RPE secretome

7 July 2018

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The extracellular matrix: not just pretty fibrils

7 July 2018

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7 July 2018

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Living beyond our physiological means: small vessel disease of the brain is an expression of a systemic failure in arteriolar function: a unifying hypothesis

7 July 2018

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7 July 2018

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Extracellular control of TGFbeta signalling in vascular development and disease

7 July 2018

1 reference

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TGF-beta signaling in vascular fibrosis.

7 July 2018

1 reference

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Genetics of ischaemic stroke

7 July 2018

1 reference

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BMP1 controls TGFbeta1 activation via cleavage of latent TGFbeta-binding protein

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246310

Highly sensitive and specific bioassay for measuring bioactive TGF-beta

7 July 2018

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Implications of the serine protease HtrA1 in amyloid precursor protein processing

7 July 2018

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Fibronectin regulates latent transforming growth factor-beta (TGF beta) by controlling matrix assembly of latent TGF beta-binding protein-1.

7 July 2018

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HtrA1 serine protease inhibits signaling mediated by Tgfbeta family proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246310

Latent transforming growth factor-beta 1 associates to fibroblast extracellular matrix via latent TGF-beta binding protein

7 July 2018

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Association of HTRA1 mutations and familial ischemic cerebral small-vessel disease.

7 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1418087111

HtrA1-dependent proteolysis of TGF-beta controls both neuronal maturation and developmental survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1418087111

MT1-MMP releases latent TGF-beta1 from endothelial cell extracellular matrix via proteolytic processing of LTBP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1418087111

Proteolysis of latent transforming growth factor-beta (TGF-beta )-binding protein-1 by osteoclasts. A cellular mechanism for release of TGF-beta from bone matrix.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1418087111

Fibronectin is required for integrin alphavbeta6-mediated activation of latent TGF-beta complexes containing LTBP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1418087111

Latent TGF-beta binding protein LTBP-1 contains three potential extracellular matrix interacting domains.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246310

A novel mutation in the HTRA1 gene causes CARASIL without alopecia

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25369932

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1418087111

1 reference

3 August 2017

0 references

1 reference

3 August 2017

1 reference