(Q34593795)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23427046%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

title

Identification of small-molecule inhibitors of the ribonuclease H2 enzyme (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23427046%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

5

1 reference

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24 February 2020

author name string

Rachel White

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23427046%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Barbara Saxty

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23427046%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Jonathan Large

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23427046%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Catherine A Kettleborough

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23427046%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

publication date

20 February 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23427046%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biomolecular Screening

24 February 2020

published in

1 reference

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24 February 2020

volume

18

1 reference

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24 February 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23427046%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

page(s)

610-620

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23427046%20AND%20SRC:MED&resulttype=core&format=json

Enzymes and reactions at the eukaryotic DNA replication fork

24 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1177%2F1087057113476550

RNase H2 of Saccharomyces cerevisiae is a complex of three proteins

21 January 2018

1 reference

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Abundant ribonucleotide incorporation into DNA by yeast replicative polymerases

21 January 2018

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Genome instability due to ribonucleotide incorporation into DNA.

21 January 2018

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Enzymatic removal of ribonucleotides from DNA is essential for mammalian genome integrity and development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113476550

Mammalian RNase H2 removes ribonucleotides from DNA to maintain genome integrity

21 January 2018

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https://api.crossref.org/works/10.1177%2F1087057113476550

Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutières syndrome and mimic congenital viral brain infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113476550

The Structure of the Human RNase H2 Complex Defines Key Interaction Interfaces Relevant to Enzyme Function and Human Disease

21 January 2018

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Nucleic acid-mediated inflammatory diseases

21 January 2018

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Trex1 exonuclease degrades ssDNA to prevent chronic checkpoint activation and autoimmune disease

21 January 2018

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Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 cause Aicardi-Goutières syndrome at the AGS1 locus

21 January 2018

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Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus

21 January 2018

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Genomics screen in transformed stem cells reveals RNASEH2A, PPAP2C, and ADARB1 as putative anticancer drug targets.

21 January 2018

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A fluorescence-based high-throughput screening assay for inhibitors of human immunodeficiency virus-1 reverse transcriptase-associated ribonuclease H activity

21 January 2018

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Vinylogous ureas as a novel class of inhibitors of reverse transcriptase-associated ribonuclease H activity

21 January 2018

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Selective inhibition of HIV-1 reverse transcriptase-associated ribonuclease H activity by hydroxylated tropolones

21 January 2018

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Crystal Structures of RNase H2 in Complex with Nucleic Acid Reveal the Mechanism of RNA-DNA Junction Recognition and Cleavage

21 January 2018

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Use of the pharmacological inhibitor BX795 to study the regulation and physiological roles of TBK1 and IkappaB kinase epsilon: a distinct upstream kinase mediates Ser-172 phosphorylation and activation

21 January 2018

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Identification of small molecule inhibitors of phosphatidylinositol 3-kinase and autophagy.

21 January 2018

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In vitro biological activity of a novel small-molecule inhibitor of polo-like kinase 1.

21 January 2018

1 reference

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Discovery of a Novel Class of Covalent Inhibitor for Aldehyde Dehydrogenases

21 January 2018

1 reference

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