(Q34600909)

English

Antiproliferative activity of PEP005, a novel ingenol angelate that modulates PKC functions, alone and in combination with cytotoxic agents in human colon cancer cells.

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19034280%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Antiproliferative activity of PEP005, a novel ingenol angelate that modulates PKC functions, alone and in combination with cytotoxic agents in human colon cancer cells (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19034280%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

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1 reference

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inferred from title

Steven M Ogbourne

6

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19034280%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

9

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19034280%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Sandrine Faivre

10

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19034280%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

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K A Benhadji

1

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Europe PubMed Central

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17 January 2020

M Serova

2

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17 January 2020

A Ghoul

3

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17 January 2020

E Cvitkovic

4

1 reference

Europe PubMed Central

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17 January 2020

C Le Tourneau

5

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19034280%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

F Lokiec

7

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Europe PubMed Central

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17 January 2020

F Calvo

8

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17 January 2020

E Raymond

11

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Europe PubMed Central

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17 January 2020

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publication date

1 December 2008

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17 January 2020

British Journal of Cancer

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19034280%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

99

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Europe PubMed Central

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17 January 2020

11

1 reference

Europe PubMed Central

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17 January 2020

1808-1815

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19034280%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

https://scigraph.springernature.com/pub.10.1038/sj.bjc.6604642

0 references

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600681

7 July 2018

Protein kinase C and other diacylglycerol effectors in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600681

7 July 2018

Induction of senescence in diterpene ester-treated melanoma cells via protein kinase C-dependent hyperactivation of the mitogen-activated protein kinase pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600681

7 July 2018

Preclinical and clinical development of novel agents that target the protein kinase C family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600681

7 July 2018

Phase III study of gemcitabine and cisplatin with or without aprinocarsen, a protein kinase C-alpha antisense oligonucleotide, in patients with advanced-stage non-small-cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600681

7 July 2018

Involvement of proteolytic activation of PKCdelta in cisplatin-induced apoptosis in human small cell lung cancer H69 cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600681

7 July 2018

Ingenol 3-angelate induces dual modes of cell death and differentially regulates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in melanoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600681

7 July 2018

Characterization of the interaction of ingenol 3-angelate with protein kinase C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600681

7 July 2018

Antitumor activity of 3-ingenyl angelate: plasma membrane and mitochondrial disruption and necrotic cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600681

7 July 2018

Protein kinase C (PKC) betaII induces cell invasion through a Ras/Mek-, PKC iota/Rac 1-dependent signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600681

7 July 2018

Antiangiogenic and antitumor effects of a protein kinase Cbeta inhibitor in human HT-29 colon carcinoma and human CaKi1 renal cell carcinoma xenografts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600681

7 July 2018

Characterization of protein kinase C beta isoform's action on retinoblastoma protein phosphorylation, vascular endothelial growth factor-induced endothelial cell proliferation, and retinal neovascularization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600681

7 July 2018

Tyrosine phosphorylation of protein kinase Cdelta is essential for its apoptotic effect in response to etoposide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600681

7 July 2018

Colonocyte differentiation is associated with increased expression and altered distribution of protein kinase C isozymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600681

7 July 2018

Expression of protein kinase C isoenzymes in colorectal cancer tissue and their differential activation by different bile acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600681

7 July 2018

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600681

7 July 2018

PEP005, a selective small-molecule activator of protein kinase C, has potent antileukemic activity mediated via the delta isoform of PKC.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6604642

21 January 2018

Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6604642

21 January 2018

Suppression of apoptosis in the protein kinase Cdelta null mouse in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6604642

21 January 2018

Targeting the protein kinase C family: are we there yet?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6604642

21 January 2018

Effects of protein kinase C modulation by PEP005, a novel ingenol angelate, on mitogen-activated protein kinase and phosphatidylinositol 3-kinase signaling in cancer cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6604642

21 January 2018

The in vivo effect of bryostatin-1 on paclitaxel-induced tumor growth, mitotic entry, and blood flow

1 reference

https://pubmed.ncbi.nlm.nih.gov/19034280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of protein kinase Cdelta in human myeloid leukemia cells treated with 1-beta-D-arabinofuranosylcytosine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19034280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SJ.BJC.6604642

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19034280%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Dimensions Publication ID

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1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19034280%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19034280%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

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