(Q34606492)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17255106%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

title

ADAMTS-5 deficiency does not block aggrecanolysis at preferred cleavage sites in the chondroitin sulfate-rich region of aggrecan (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17255106%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17255106%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Amanda Fosang

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17255106%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

author name string

Charlotte J East

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17255106%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Suzanne B Golub

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17255106%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Fraser M Rogerson

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17255106%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

language of work or name

English

0 references

publication date

25 January 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17255106%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

24 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17255106%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

volume

282

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17255106%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17255106%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

page(s)

8632-8640

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17255106%20AND%20SRC:MED&resulttype=core&format=json

Increased vulnerability of postarthritic cartilage to a second arthritic insult: accelerated MMP activity in a flare up of arthritis

24 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

N-terminal sequence of proteoglycan fragments isolated from medium of interleukin-1-treated articular-cartilage cultures. Putative site(s) of enzymic cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

Mechanism of catabolism of aggrecan by articular cartilage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

The structure of aggrecan fragments in human synovial fluid. Evidence for the involvement in osteoarthritis of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

Purification and cloning of aggrecanase-1: a member of the ADAMTS family of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

ADAMTS-1 cleaves a cartilage proteoglycan, aggrecan

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

ADAMTS-8 exhibits aggrecanase activity and is expressed in human articular cartilage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

Characterization of ADAMTS-9 and ADAMTS-20 as a distinct ADAMTS subfamily related to Caenorhabditis elegans GON-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

The ADAMTS metalloproteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

ADAMTS proteinases: a multi-domain, multi-functional family with roles in extracellular matrix turnover and arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

Sites of aggrecan cleavage by recombinant human aggrecanase-1 (ADAMTS-4)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

Characterization of human aggrecanase 2 (ADAM-TS5): substrate specificity studies and comparison with aggrecanase 1 (ADAM-TS4).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

Analysis of aggrecan in human knee cartilage and synovial fluid indicates that aggrecanase (ADAMTS) activity is responsible for the catabolic turnover and loss of whole aggrecan whereas other protease activity is required for C-terminal processing i

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

Growth inhibition and DNA damage induced by Cre recombinase in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

Illegitimate Cre-dependent chromosome rearrangements in transgenic mouse spermatids

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

A direct spectrophotometric microassay for sulfated glycosaminoglycans in cartilage cultures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

A new mathematical model for relative quantification in real-time RT-PCR

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

Adamts-1 is essential for the development and function of the urogenital system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

ADAMTS-1: a metalloproteinase-disintegrin essential for normal growth, fertility, and organ morphology and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

Characterization of and osteoarthritis susceptibility in ADAMTS-4-knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

ADAMTS5-mediated aggrecanolysis in murine epiphyseal chondrocyte cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

Generation and novel distribution of matrix metalloproteinase-derived aggrecan fragments in porcine cartilage explants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

Chondrocyte-mediated catabolism of aggrecan: aggrecanase-dependent cleavage induced by interleukin-1 or retinoic acid can be inhibited by glucosamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

Altered proteolytic activities of ADAMTS-4 expressed by C-terminal processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

Activation of the proteolytic activity of ADAMTS4 (aggrecanase-1) by C-terminal truncation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

Variations in aggrecan structure modulate its susceptibility to aggrecanases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

Oncostatin M in combination with tumour necrosis factor {alpha} induces a chondrocyte membrane associated aggrecanase that is distinct from ADAMTS aggrecanase-1 or -2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

Matrix metalloproteinases are not essential for aggrecan turnover during normal skeletal growth and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

Characterization of aggrecan retained and lost from the extracellular matrix of articular cartilage. Involvement of carboxyl-terminal processing in the catabolism of aggrecan

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

Aggrecan degradation in human cartilage. Evidence for both matrix metalloproteinase and aggrecanase activity in normal, osteoarthritic, and rheumatoid joints

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

Aggrecan is degraded by matrix metalloproteinases in human arthritis. Evidence that matrix metalloproteinase and aggrecanase activities can be independent

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

The mechanism of aggrecan release from cartilage differs with tissue origin and the agent used to stimulate catabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

Hyaluronate degradation as an alternative mechanism for proteoglycan release from cartilage during interleukin-1beta-stimulated catabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

Release of hyaluronan and hyaladherins (aggrecan G1 domain and link proteins) from articular cartilage exposed to ADAMTS-4 (aggrecanase 1) or ADAMTS-5 (aggrecanase 2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200

Cartilage degradation independent of MMP/aggrecanases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605750200