(Q34617941)

3 August 2017

title

Antagonism of a zinc metalloprotease using a unique metal-chelating scaffold: tropolones as inhibitors of P. aeruginosa elastase (English)

1 reference

3 August 2017

Seth M Cohen

9

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author name string

Jessica L Fullagar

1

1 reference

3 August 2017

Amanda L Garner

2

1 reference

3 August 2017

Anjali K Struss

3

1 reference

3 August 2017

Joshua A Day

4

1 reference

3 August 2017

David P Martin

5

1 reference

3 August 2017

Jing Yu

6

1 reference

3 August 2017

Xiaoqing Cai

7

1 reference

3 August 2017

Kim D Janda

8

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3 August 2017

language of work or name

English

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publication date

12 March 2013

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3 August 2017

published in

Chemical Communications

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3 August 2017

volume

49

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3 August 2017

issue

31

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3 August 2017

page(s)

3197-3199

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3-Hydroxy-1-alkyl-2-methylpyridine-4(1H)-thiones: Inhibition of the Pseudomonas aeruginosa Virulence Factor LasB.

3 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618488

Crystal structure of Agaricus bisporus mushroom tyrosinase: identity of the tetramer subunits and interaction with tropolone

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618488

Synthesis, Activity, and Structural Analysis of Novel α-Hydroxytropolone Inhibitors of Human Immunodeficiency Virus Reverse Transcriptase-Associated Ribonuclease H

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618488

Novel inhibitors of the Pseudomonas aeruginosa virulence factor LasB: a potential therapeutic approach for the attenuation of virulence mechanisms in pseudomonal infection

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618488

Cell density and mobility protect swarming bacteria against antibiotics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618488

Chelator fragment libraries for targeting metalloproteinases.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618488

Productive steps toward an antimicrobial targeting virulence

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618488

Ligand efficiency and fragment-based drug discovery

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618488

A fresh look at natural tropolonoids

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618488

Swarming of Pseudomonas aeruginosa is a complex adaptation leading to increased production of virulence factors and antibiotic resistance

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618488

Plant troponoids: chemistry, biological activity, and biosynthesis.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618488

Targeting virulence: a new paradigm for antimicrobial therapy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618488

Pseudomonas aeruginosa: resistance and therapeutic options at the turn of the new millennium.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618488

Bacterial proteinases as targets for the development of second-generation antibiotics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618488

Contribution of toxin A and elastase to virulence of Pseudomonas aeruginosa in chronic lung infections of rats.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618488

Pseudomonas aeruginosa elastase. Development of a new substrate, inhibitors, and an affinity ligand.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618488

Pseudomonas aeruginosa elastase and its role in pseudomonas infections.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618488

Three-dimensional structure of the elastase of Pseudomonas aeruginosa at 1.5-A resolution

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618488

Biological Activity of Tropolone

7 July 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CC41191E

Identifying chelators for metalloprotein inhibitors using a fragment-based approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CC41191E

Fragment-based drug design: how big is too big?

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CC41191E

Swarming motility: a multicellular behaviour conferring antimicrobial resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CC41191E

Cellular function of elastase in Pseudomonas aeruginosa: role in the cleavage of nucleoside diphosphate kinase and in alginate synthesis

21 January 2018

1 reference

12 December 2020

PSEUDOMONAS AERUGINOSA ELASTASE. ISOLATION, CRYSTALLIZATION, AND PRELIMINARY CHARACTERIZATION

1 reference

12 December 2020

Monoaryl- and bisaryldihydroxytropolones as potent inhibitors of inositol monophosphatase

1 reference

12 December 2020

Immunization with a Pseudomonas aeruginosa elastase peptide reduces severity of experimental lung infections due to P. aeruginosa Or Burkholderia cepacia

1 reference

12 December 2020

Identifiers

DOI

10.1039/C3CC41191E

1 reference

3 August 2017

1 reference

3 August 2017

1 reference