(Q34618624)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24997502%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

title

Computational analysis of image-based drug profiling predicts synergistic drug combinations: applications in triple-negative breast cancer (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24997502%20AND%20SRC:MED&resulttype=core&format=json

triple-negative breast cancer

21 March 2020

main subject

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24997502%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

7

Maria Kavallaris

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24997502%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

8

Stephen T C Wong

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24997502%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

author name string

Miriam B Brandl

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24997502%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Fuhai Li

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24997502%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Dominik Beck

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24997502%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Sufang Zhang

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24997502%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Hong Zhao

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24997502%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

publication date

19 June 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24997502%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24997502%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24997502%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24997502%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

page(s)

1548-1560

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24997502%20AND%20SRC:MED&resulttype=core&format=json

TORC1 and class I HDAC inhibitors synergize to suppress mature B cell neoplasms

21 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4253311

Defining principles of combination drug mechanisms of action

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4253311

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4253311

Activity of the kinesin spindle protein inhibitor ispinesib (SB-715992) in models of breast cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4253311

Synergistic drug combinations tend to improve therapeutically relevant selectivity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4253311

Algorithmic guided screening of drug combinations of arbitrary size for activity against cancer cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4253311

Search algorithms as a framework for the optimization of drug combinations

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4253311

Models from experiments: combinatorial drug perturbations of cancer cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4253311

An image score inference system for RNAi genome-wide screening based on fuzzy mixture regression modeling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4253311

Microtubules: a dynamic target in cancer therapy.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4253311

Closed-loop control of cellular functions using combinatory drugs guided by a stochastic search algorithm

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4253311

Triple negative tumours: a critical review

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4253311

Optimizing combination chemotherapy by controlling drug ratios

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4253311

Imaging in systems biology

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4253311

Rational design of cancer-drug combinations

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4253311

The triple negative paradox: primary tumor chemosensitivity of breast cancer subtypes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4253311

Targeted anti-mitotic therapies: can we improve on tubulin agents?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4253311

Multi-target therapeutics: when the whole is greater than the sum of the parts

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4253311

Disassembly of actin filaments by botulinum C2 toxin and actin-filament-disrupting agents induces assembly of microtubules in human leukaemia cell lines

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4253311

Strategies for optimizing combinations of molecularly targeted anticancer agents

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4253311

7 July 2018

Biological robustness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4253311

Microtubules as a target for anticancer drugs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4253311

Systematic discovery of multicomponent therapeutics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4253311

Principles for the buffering of genetic variation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4253311

Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4253311

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4253311

Combination chemotherapy of Hodgkin's disease with adriamycin, bleomycin, vinblastine, and imidazole carboxamide versus MOPP

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4253311

Development and biological evaluation of potent and specific inhibitors of mitotic Kinesin Eg5.

7 July 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLONC.2014.06.007

A robustness-based approach to systems-oriented drug design.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLONC.2014.06.007

Differential effects of monastrol in two human cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLONC.2014.06.007

An automated feedback system with the hybrid model of scoring and classification for solving over-segmentation problems in RNAi high content screening.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLONC.2014.06.007

Response to neoadjuvant therapy and long-term survival in patients with triple-negative breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLONC.2014.06.007

ENMD-1198, a new analogue of 2-methoxyestradiol, displays both antiangiogenic and vascular-disrupting properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLONC.2014.06.007

Synthesis and biological evaluation of novel EG5 inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLONC.2014.06.007

Mitomycin C and vinblastine: an active regimen in previously treated breast cancer patients.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4253311

Mechanism of mitotic block and inhibition of cell proliferation by the semisynthetic Vinca alkaloids vinorelbine and its newer derivative vinflunine.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4253311

Microtubule disruption induces the formation of actin stress fibers and focal adhesions in cultured cells: possible involvement of the rho signal cascade.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4253311

Locoregional Relapse and Distant Metastasis in Conservatively Managed Triple Negative Early-Stage Breast Cancer

26 October 2018

1 reference

12 December 2020

How valid are claims for synergy in published clinical studies?

1 reference

12 December 2020

Mechanisms of drug combinations: interaction and network perspectives

1 reference

12 December 2020

Image-based multivariate profiling of drug responses from single cells

1 reference

12 December 2020

10.1016/J.MOLONC.2014.06.007

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24997502%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24997502%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

PubMed publication ID

24997502

1 reference