(Q34626429)

3 August 2017

Mapping the cellular response to small molecules using chemogenomic fitness signatures (English)

1 reference

3 August 2017

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24723613%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Iain M Wallace

4

1 reference

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13 June 2020

Aaron H Nile

5

1 reference

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13 June 2020

Paul A. Spagnuolo

6

1 reference

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13 June 2020

Mitchell K L Han

14

1 reference

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13 June 2020

Lawrence E Heisler

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24723613%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Carolyn L. Cummins

32

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24723613%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Grant W Brown

34

1 reference

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13 June 2020

Aaron Schimmer

35

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24723613%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Gary D. Bader

38

1 reference

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13 June 2020

8

Marcela Gronda

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24723613%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

author name string

Anna Y Lee

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24723613%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Robert P St Onge

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24723613%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Michael J Proctor

3

1 reference

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13 June 2020

Yulia Jitkova

7

1 reference

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13 June 2020

Yan Wu

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24723613%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Moshe K Kim

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24723613%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Kahlin Cheung-Ong

11

1 reference

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13 June 2020

Nikko P Torres

12

1 reference

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13 June 2020

Eric D Spear

13

1 reference

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13 June 2020

Ulrich Schlecht

15

1 reference

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13 June 2020

Sundari Suresh

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24723613%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Geoffrey Duby

17

1 reference

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13 June 2020

Anuradha Surendra

19

1 reference

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13 June 2020

Eula Fung

20

1 reference

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13 June 2020

Malene L Urbanus

21

1 reference

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13 June 2020

Marinella Gebbia

22

1 reference

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13 June 2020

Elena Lissina

23

1 reference

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13 June 2020

Molly Miranda

24

1 reference

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13 June 2020

Jennifer H Chiang

25

1 reference

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13 June 2020

Ana Maria Aparicio

26

1 reference

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13 June 2020

Mahel Zeghouf

27

1 reference

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13 June 2020

Ronald W Davis

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24723613%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Jacqueline Cherfils

29

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24723613%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Chris A Kaiser

31

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24723613%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

William S Trimble

33

1 reference

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13 June 2020

Vytas A Bankaitis

36

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24723613%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Corey Nislow

37

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24723613%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Guri Giaever

39

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24723613%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

language of work or name

English

0 references

publication date

1 April 2014

1 reference

3 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24723613%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

volume

344

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24723613%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

issue

6180

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24723613%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

page(s)

208-211

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24723613%20AND%20SRC:MED&resulttype=core&format=json

PITPs as targets for selectively interfering with phosphoinositide signaling in cells

13 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254748

A high-throughput yeast assay identifies synergistic drug combinations

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254748

The BioGRID interaction database: 2013 update

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254748

Cystic fibrosis in an era of genomically guided therapy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254748

Mitochondrial electron transport is the cellular target of the oncology drug elesclomol

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254748

Inhibition of mitochondrial translation as a therapeutic strategy for human acute myeloid leukemia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254748

Compound prioritization methods increase rates of chemical probe discovery in model organisms

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254748

Discovery of drug mode of action and drug repositioning from transcriptional responses

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254748

The antidepressant sertraline targets intracellular vesiculogenic membranes in yeast

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254748

The genetic landscape of a cell

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254748

Forchlorfenuron alters mammalian septin assembly, organization, and dynamics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254748

The chemical genomic portrait of yeast: uncovering a phenotype for all genes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254748

The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254748

Drug-induced phospholipidosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254748

Chemogenomic profiling: identifying the functional interactions of small molecules in yeast

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254748

Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254748

Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254748

Functional profiling of the Saccharomyces cerevisiae genome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254748

Drug-induced phospholipidosis: are there functional consequences?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254748

Genomic profiling of drug sensitivities via induced haploinsufficiency.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254748

Kes1p shares homology with human oxysterol binding protein and participates in a novel regulatory pathway for yeast Golgi-derived transport vesicle biogenesis.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254748

Mutations in the CDP-choline pathway for phospholipid biosynthesis bypass the requirement for an essential phospholipid transfer protein

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254748

Identification of small molecules enhancing autophagic function from drug network analysis

7 July 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250217

An integrated platform of genomic assays reveals small-molecule bioactivities

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250217

Genome-wide analysis of barcoded Saccharomyces cerevisiae gene-deletion mutants in pooled cultures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250217

Sulforhodamine B colorimetric assay for cytotoxicity screening.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250217

A unique and universal molecular barcode array

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250217

An improved method for scoring protein-protein interactions using semantic similarity within the gene ontology

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250217

Supervised normalization of microarrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250217

A consensus of core protein complex compositions for Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250217

GO-Elite: a flexible solution for pathway and ontology over-representation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250217

Enrichment map: a network-based method for gene-set enrichment visualization and interpretation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250217

Cytoscape 2.8: new features for data integration and network visualization

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250217

The properties of known drugs. 1. Molecular frameworks

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250217

Cationic amphiphilic drug-induced phospholipidosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250217

Open Babel: An open chemical toolbox

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250217

Defining clusters from a hierarchical cluster tree: the Dynamic Tree Cut package for R.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250217

Iterative signature algorithm for the analysis of large-scale gene expression data

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250217

Using extended-connectivity fingerprints with Laplacian-modified Bayesian analysis in high-throughput screening follow-up

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250217

Probing the links between in vitro potency, ADMET and physicochemical parameters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250217

Functional anatomy of phospholipid binding and regulation of phosphoinositide homeostasis by proteins of the sec14 superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250217

Resurrection of a functional phosphatidylinositol transfer protein from a pseudo-Sec14 scaffold by directed evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250217

Yeast Sec14p deficient in phosphatidylinositol transfer activity is functional in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250217

Identification of a novel family of nonclassic yeast phosphatidylinositol transfer proteins whose function modulates phospholipase D activity and Sec14p-independent cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250217

The antihelmintic flubendazole inhibits microtubule function through a mechanism distinct from Vinca alkaloids and displays preclinical activity in leukemia and myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250217

HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250217

Assessment of mitochondrial oxidative phosphorylation in patient muscle biopsies, lymphoblasts, and transmitochondrial cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250217

Evidence in a lethal infantile mitochondrial disease for a nuclear mutation affecting respiratory complexes I and IV.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250217

Distinct retrieval and retention mechanisms are required for the quality control of endoplasmic reticulum protein folding

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250217

Physiological regulation of membrane protein sorting late in the secretory pathway of Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250217

Activity-dependent reversible inactivation of the general amino acid permease

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250217

Prediction of 'drug-likeness'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250217

Requirement for ergosterol in V-ATPase function underlies antifungal activity of azole drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250217

Combining probability from independent tests: the weighted Z-method is superior to Fisher's approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250217

21 January 2018

Identifiers

DOI

10.1126/SCIENCE.1250217

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24723613%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24723613%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24723613%20AND%20SRC:MED&resulttype=core&format=json