(Q34627084)

3 August 2017

title

Solid-phase methodology for synthesis of O-alkylated aromatic oligoamide inhibitors of α-helix-mediated protein-protein interactions (English)

1 reference

Design and Synthesis of Functional Aromatic Oligoamide Foldamers

3 August 2017

sponsor

1 reference

Gateway to Research Project ID

Gateway to Research

EP/D077842/1

protein-protein interaction

27 April 2019

main subject

1 reference

8

Andrew J Wilson

1 reference

3 August 2017

7

1 reference

3 August 2017

Jeffrey P Plante

4

0 references

Michaele J Hardie

object named as

Michaele J Hardie

5

0 references

author name string

Natasha S Murphy

1

1 reference

3 August 2017

Panchami Prabhakaran

2

1 reference

3 August 2017

Valeria Azzarito

3

1 reference

3 August 2017

Colin A Kilner

6

1 reference

3 August 2017

language of work or name

English

0 references

publication date

18 March 2013

1 reference

full work available at URL

3 August 2017

http://eprints.whiterose.ac.uk/83421

content deliverer

White Rose Research Online

object has role

published version

1 reference

White Rose Research Online

http://eprints.whiterose.ac.uk/83421

Chemistry—A European Journal

15 December 2018

published in

1 reference

3 August 2017

volume

19

1 reference

3 August 2017

issue

18

1 reference

3 August 2017

page(s)

5546-5550

1 reference

Aromatic amide foldamers: structures, properties, and functions

3 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743211

Microwave-enhanced solid-phase synthesis of N,N'-linked aliphatic oligoureas and related hybrids

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743211

Evaluation of Diverse α/β-Backbone Patterns for Functional α-Helix Mimicry: Analogues of the Bim BH3 Domain

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743211

Assessing helical protein interfaces for inhibitor design

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743211

An orthosteric inhibitor of the Ras-Sos interaction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743211

Solid-phase synthesis of tris-benzamides as α-helix mimetics.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743211

Novel pyrrolopyrimidine-based α-helix mimetics: cell-permeable inhibitors of protein−protein interactions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743211

Solid phase synthesis of aromatic oligoamides: application to helical water-soluble foldamers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743211

Oligobenzamide proteomimetic inhibitors of the p53-hDM2 protein-protein interaction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743211

Disrupting protein-protein interactions with non-peptidic, small molecule alpha-helix mimetics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743211

Synthetic alpha-helix mimetics as agonists and antagonists of islet amyloid polypeptide aggregation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743211

Isolation of antagonists of antigen-specific autoimmune T cell proliferation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743211

Structural and biological mimicry of protein surface recognition by / -peptide foldamers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743211

Design, synthesis, and evaluation of an alpha-helix mimetic library targeting protein-protein interactions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743211

Beta-peptides with improved affinity for hDM2 and hDMX.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743211

alpha-Helix mimetics as inhibitors of protein-protein interactions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743211

Principles of protein-protein interactions: what are the preferred ways for proteins to interact?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743211

Reaching for high-hanging fruit in drug discovery at protein-protein interfaces

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743211

Foldamers as versatile frameworks for the design and evolution of function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743211

The world of beta- and gamma-peptides comprised of homologated proteinogenic amino acids and other components

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743211

Strategies for targeting protein-protein interactions with synthetic agents.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743211

A field guide to foldamers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743211

beta-Peptides: from structure to function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743211

Sequence-specific polypeptoids: a diverse family of heteropolymers with stable secondary structure

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743211

Synthesis of functionalised aromatic oligamide rods

7 July 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201204098

N-alkylated oligoamide alpha-helical proteomimetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201204098

2-O-alkylated para-benzamide α-helix mimetics: the role of scaffold curvature.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201204098

Controlling curvature in a family of oligoamide alpha-helix mimetics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201204098

Structure and function of benzoylurea-derived alpha-helix mimetics targeting the Bcl-x(L)/Bak binding interface

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201204098

Toward proteomimetics: terphenyl derivatives as structural and functional mimics of extended regions of an alpha-helix

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201204098

Nanosized hybrid oligoamide foldamers: aromatic templates for the folding of multiple aliphatic units.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201204098

Conformational properties of O-alkylated benzamides

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201204098

Chimeric (alpha/beta + alpha)-peptide ligands for the BH3-recognition cleft of Bcl-XL: critical role of the molecular scaffold in protein surface recognition

21 January 2018

1 reference

12 December 2020

Novel amphiphilic alpha-helix mimetics based on a bis-benzamide scaffold

1 reference

12 December 2020

Proteomorphous objects from abiotic backbones

1 reference

12 December 2020

Fmoc solid phase synthesis of polyamides containing pyrrole and imidazole amino acids

1 reference

12 December 2020

Solid-phase synthesis of oligo(p-benzamide) foldamers

1 reference

12 December 2020

Probing the structural requirements of peptoids that inhibit HDM2-p53 interactions

1 reference

12 December 2020

Application of microwave irradiation to the synthesis of 14-helical beta-peptides

1 reference

12 December 2020

Identifiers

DOI

10.1002/CHEM.201204098

1 reference

Dimensions Publication ID

3 August 2017

Altmetric DOI

10.1002/CHEM.201204098

0 references

0 references

1 reference

3 August 2017

1 reference