(Q34627236)

3 August 2017

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title

v-Src's hold over actin and cell adhesions (English)

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3 August 2017

Neil O Carragher

3

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Margaret Frame

series ordinal

1

object named as

Margaret C Frame

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3 August 2017

2

Valerie J Fincham

1 reference

3 August 2017

John A Wyke

4

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3 August 2017

1 April 2002

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Nature Reviews Molecular Cell Biology

3 August 2017

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3 August 2017

3

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3 August 2017

233-245

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3 August 2017

4

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https://scigraph.springernature.com/pub.10.1038/nrm779

3 August 2017

0 references

cites work

Transforming gene product of Rous sarcoma virus phosphorylates tyrosine

1 reference

31 March 2020

The hunting of the Src

1 reference

The use of Rous sarcoma virus transformation mutants with differing tyrosine kinase activities to study the relationships between vinculin phosphorylation, pp60v-src location and adhesion plaque integrity

31 March 2020

1 reference

Altered distributions of the cytoskeletal proteins vinculin and alpha-actinin in cultured fibroblasts transformed by Rous sarcoma virus

31 March 2020

1 reference

Early changes in the distribution and organization of microfilament proteins during cell transformation

31 March 2020

1 reference

Organization of pp60src and selected cytoskeletal proteins within adhesion plaques and junctions of Rous sarcoma virus-transformed rat cells

31 March 2020

1 reference

Cell transformation by the viral src oncogene

31 March 2020

1 reference

Phosphorylation of vinculin by pp60src: What might it mean?

31 March 2020

1 reference

Membrane and cytoskeletal changes in cells after transformation by Rous sarcoma virus

31 March 2020

1 reference

Transformation Parameters and pp60src Localization in Cells Infected with Partial Transformation Mutants of Rous Sarcoma Virus

31 March 2020

1 reference

Tyr527 is phosphorylated in pp60c-src: implications for regulation

31 March 2020

1 reference

Cellular functions regulated by Src family kinases

31 March 2020

1 reference

Localization of the ASV src gene product to the plasma membrane of transformed cells by electron microscopic immunocytochemistry

31 March 2020

1 reference

Immunofluorescence on avian sarcoma virus-transformed cells: Localization of the src gene product

31 March 2020

1 reference

The protein encoded by the transforming gene of avian sarcoma virus (pp60src) and a homologous protein in normal cells (pp60proto-src) are associated with the plasma membrane

31 March 2020

1 reference

Size-Variant pp60src Proteins of Recovered Avian Sarcoma Viruses Interact with Adhesion Plaques as Peripheral Membrane Proteins: Effects on Cell Transformation

31 March 2020

1 reference

Immunofluorescent localization of the transforming protein of Rous sarcoma virus with antibodies against a synthetic src peptide

31 March 2020

1 reference

Translocation of Src kinase to the cell periphery is mediated by the actin cytoskeleton under the control of the Rho family of small G proteins

31 March 2020

1 reference

The SH3 domain directs acto-myosin-dependent targeting of v-Src to focal adhesions via phosphatidylinositol 3-kinase

31 March 2020

1 reference

The catalytic activity of Src is dispensable for translocation to focal adhesions but controls the turnover of these structures during cell motility

31 March 2020

1 reference

Mutational analysis of the Src SH3 domain: the same residues of the ligand binding surface are important for intra- and intermolecular interactions

31 March 2020

1 reference

v-Src SH3-enhanced interaction with focal adhesion kinase at beta 1 integrin-containing invadopodia promotes cell invasion

31 March 2020

1 reference

Association of p60c-src with endosomal membranes in mammalian fibroblasts

31 March 2020

1 reference

Coordination of cell polarization and migration by the Rho family GTPases requires Src tyrosine kinase activity

31 March 2020

1 reference

Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting

31 March 2020

1 reference

ASAP1, a phospholipid-dependent arf GTPase-activating protein that associates with and is phosphorylated by Src.

31 March 2020

1 reference

The Arf GTPase-activating protein ASAP1 regulates the actin cytoskeleton

31 March 2020

1 reference

Intracellular movement of green fluorescent protein-tagged phosphatidylinositol 3-kinase in response to growth factor receptor signaling

31 March 2020

1 reference

Active ERK/MAP kinase is targeted to newly forming cell-matrix adhesions by integrin engagement and v-Src

31 March 2020

1 reference

The protrusive phase and full development of integrin-dependent adhesions in colon epithelial cells require FAK- and ERK-mediated actin spike formation: deregulation in cancer cells

31 March 2020

1 reference

Phosphorylation of paxillin via the ERK mitogen-activated protein kinase cascade in EL4 thymoma cells

31 March 2020

1 reference

Regulation of nucleocytoplasmic trafficking by cell adhesion receptors and the cytoskeleton

31 March 2020

1 reference

Integrin-mediated adhesion regulates ERK nuclear translocation and phosphorylation of Elk-1

31 March 2020

1 reference

Rous sarcoma virus-transformed fibroblasts adhere primarily at discrete protrusions of the ventral membrane called podosomes

31 March 2020

1 reference

Cortactin, an 80/85-kilodalton pp60src substrate, is a filamentous actin-binding protein enriched in the cell cortex

31 March 2020

1 reference

Differentiation dependent expression of tensin and cortactin in chicken osteoclasts.

31 March 2020

1 reference

Down-regulation of the filamentous actin cross-linking activity of cortactin by Src-mediated tyrosine phosphorylation.

31 March 2020

1 reference

Cortactin localization to sites of actin assembly in lamellipodia requires interactions with F-actin and the Arp2/3 complex

31 March 2020

1 reference

Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation

31 March 2020

1 reference

Identification and sequence analysis of cDNAs encoding a 110-kilodalton actin filament-associated pp60src substrate

31 March 2020

1 reference

Src family kinases are required for integrin but not PDGFR signal transduction.

31 March 2020

1 reference

Selective regulation of integrin--cytoskeleton interactions by the tyrosine kinase Src.

31 March 2020

1 reference

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

31 March 2020

1 reference

Activated SRC oncogene phosphorylates R-ras and suppresses integrin activity

31 March 2020

1 reference

Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases

31 March 2020

1 reference

Association between GTPase activators for Rho and Ras families.

31 March 2020

1 reference

Molecular cloning of cDNAs encoding the GAP-associated protein p190: implications for a signaling pathway from ras to the nucleus

31 March 2020

1 reference

A mutant form of the rho protein can restore stress fibers and adhesion plaques in v-src transformed fibroblasts

31 March 2020

1 reference

Integrin engagement suppresses RhoA activity via a c-Src-dependent mechanism

31 March 2020

1 reference

RhoA inactivation by p190RhoGAP regulates cell spreading and migration by promoting membrane protrusion and polarity

31 March 2020

1 reference

Role of c-Src tyrosine kinase in EGF-induced mitogenesis.

31 March 2020

1 reference

Phosphotyrosine (p-Tyr)-dependent and -independent mechanisms of p190 RhoGAP-p120 RasGAP interaction: Tyr 1105 of p190, a substrate for c-Src, is the sole p-Tyr mediator of complex formation

31 March 2020

1 reference

p190 RhoGAP is the principal Src substrate in brain and regulates axon outgrowth, guidance and fasciculation

31 March 2020

1 reference

Regulating axon branch stability: the role of p190 RhoGAP in repressing a retraction signaling pathway.

31 March 2020

1 reference

v-Src induces tyrosine phosphorylation of focal adhesion kinase independently of tyrosine 397 and formation of a complex with Src

31 March 2020

1 reference

New era of calpain research. Discovery of tissue-specific calpains

31 March 2020

1 reference

Calpain: a cytosolic proteinase active at the membranes

31 March 2020

1 reference

Identification and characterization of inhibitory sequences in four repeating domains of the endogenous inhibitor for calcium-dependent protease.

31 March 2020

1 reference

Calcium-activated neutral protease (calpain) system: structure, function, and regulation

31 March 2020

1 reference

Reduced cell migration and disruption of the actin cytoskeleton in calpain-deficient embryonic fibroblasts

31 March 2020

1 reference

Regulation of cell migration by the calcium-dependent protease calpain

31 March 2020

1 reference

Colocalization of calcium-dependent protease II and one of its substrates at sites of cell adhesion

31 March 2020

1 reference

The behavior of calpain-generated N- and C-terminal fragments of talin in integrin-mediated signaling pathways

31 March 2020

1 reference

Unphosphorylated and tyrosine-phosphorylated forms of a focal adhesion protein, paxillin, are substrates for calpain II in vitro: implications for the possible involvement of calpain II in mitosis-specific degradation of paxillin.

31 March 2020

1 reference

Focal adhesion kinase (pp125FAK) cleavage and regulation by calpain

31 March 2020

1 reference

Cutting to the chase: calpain proteases in cell motility

31 March 2020

1 reference

Cleavage of focal adhesion kinase by different proteases during SRC-regulated transformation and apoptosis. Distinct roles for calpain and caspases.

31 March 2020

1 reference

v-Src-induced modulation of the calpain-calpastatin proteolytic system regulates transformation.

31 March 2020

1 reference

Degraded collagen fragments promote rapid disassembly of smooth muscle focal adhesions that correlates with cleavage of pp125(FAK), paxillin, and talin

31 March 2020

1 reference

A negative feedback loop attenuates EGF-induced morphological changes

31 March 2020

1 reference

Altered fibronectin-dependent cell adhesion by PDGF accompanies phenotypic modulation of vascular smooth muscle cells

31 March 2020

1 reference

Membrane proximal ERK signaling is required for M-calpain activation downstream of epidermal growth factor receptor signaling.

31 March 2020

1 reference

FAK integrates growth-factor and integrin signals to promote cell migration

31 March 2020

1 reference

DNA synthesis induced by some but not all growth factors requires Src family protein tyrosine kinases.

31 March 2020

1 reference

pp60c-src is a positive regulator of growth factor-induced cell scattering in a rat bladder carcinoma cell line

31 March 2020

1 reference

Potentiation of epidermal growth factor receptor-mediated oncogenesis by c-Src: implications for the etiology of multiple human cancers

31 March 2020

1 reference

Augmented mitogenic responsiveness to epidermal growth factor in murine fibroblasts that overexpress pp60c-src

31 March 2020

1 reference

Mitotic clonal expansion during preadipocyte differentiation: calpain-mediated turnover of p27.

31 March 2020

1 reference

The mechanism of cell cycle regulation by v-Src.

31 March 2020

1 reference

Src family tyrosine kinases and growth factor signaling

31 March 2020

1 reference

V-src kinase shifts the cadherin-based cell adhesion from the strong to the weak state and beta catenin is not required for the shift

31 March 2020

1 reference

Cadherin-mediated cell-cell adhesion is perturbed by v-src tyrosine phosphorylation in metastatic fibroblasts

31 March 2020

1 reference

Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/beta-catenin complex in cells transformed with a temperature-sensitive v-SRC gene

31 March 2020

1 reference

Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex

31 March 2020

1 reference

Tyrosine phosphorylation regulates the adhesions of ras-transformed breast epithelia

31 March 2020

1 reference

Comparative study of hepatocyte growth factor/scatter factor and keratinocyte growth factor effects on human keratinocytes

31 March 2020

1 reference

Src and Ras are involved in separate pathways in epithelial cell scattering

31 March 2020

1 reference

Tyrosine phosphorylation and src family kinases control keratinocyte cell-cell adhesion.

31 March 2020

1 reference

The catalytic activity of the Src family kinases is required to disrupt cadherin-dependent cell-cell contacts

31 March 2020

1 reference

Calcium-activated proteolysis of intracellular domains in the cell adhesion molecules NCAM and N-cadherin.

31 March 2020

1 reference

Elevated calcium level induces calcium-dependent proteolysis of A-CAM (N-cadherin) in heart--analysis by detergent-treated model

31 March 2020

1 reference

31 March 2020

1 reference

The selective isolation of temperature-sensitive mutants of Rous sarcoma virus

31 March 2020

1 reference

The structure of calpain.

31 March 2020

1 reference

The binding of large calpastatin to biologic membranes is mediated in part by interaction of an amino terminal region with acidic phospholipids

31 March 2020

1 reference

Epidermal growth factor-induced tumor cell invasion and metastasis initiated by dephosphorylation and downregulation of focal adhesion kinase

31 March 2020

1 reference

A single point mutation has pleiotropic effects on pp60v-src function

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Mutations in the SH3 domain of the src oncogene which decrease association of phosphatidylinositol 3'-kinase activity with pp60v-src and alter cellular morphology

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRM779

1 reference

PubMed ID

11994743

Dimensions Publication ID

3 August 2017

1029855417

0 references

Fatcat ID

release_dqu4vuxdird3ziyfodyrpkwhua

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/dqu4vuxdird3ziyfodyrpkwhua

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

11994743

1 reference

PubMed ID

11994743