(Q34631440)

24994643

3 August 2017

title

Molecular kinetics. Ras activation by SOS: allosteric regulation by altered fluctuation dynamics (English)

1 reference

3 August 2017

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24994643%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Sune M Christensen

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24994643%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Steven Abel

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24994643%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Hung-Jen Wu

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24994643%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Dimitrios Stamou

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24994643%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Lars Lønsmann Iversen

1

object named as

Lars Iversen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24994643%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

17

Jay T Groves

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24994643%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

author name string

Wan-Chen Lin

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24994643%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Jeff Iwig

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24994643%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Jodi Gureasko

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24994643%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Christopher Rhodes

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24994643%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Rebecca S Petit

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24994643%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Scott D Hansen

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24994643%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Peter Thill

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24994643%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Cheng-Han Yu

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24994643%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Arup K Chakraborty

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24994643%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

John Kuriyan

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24994643%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

language of work or name

English

0 references

publication date

1 July 2014

1 reference

24994643

3 August 2017

number of pages

5

1 reference

based on heuristic

inferred from page(s)

published in

Science

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24994643%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

volume

345

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24994643%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

issue

6192

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24994643%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

page(s)

50-54

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24994643%20AND%20SRC:MED&resulttype=core&format=json

Regulation of ras exchange factors and cellular localization of ras activation by lipid messengers in T cells

11 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

Direct single molecule measurement of TCR triggering by agonist pMHC in living primary T cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

Higher-order assemblies in a new paradigm of signal transduction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

Encoding and decoding cellular information through signaling dynamics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

Regulation of small GTPases by GEFs, GAPs, and GDIs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

N-Ras forms dimers at POPC membranes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

Allostery and the Monod-Wyman-Changeux model after 50 years

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

Signaling clusters in the cell membrane

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

T-cell triggering thresholds are modulated by the number of antigen within individual T-cell receptor clusters

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

Signaling from the living plasma membrane

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

Induced fit, conformational selection and independent dynamic segments: an extended view of binding events

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

Signalling ballet in space and time

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

Molecular mechanisms in signal transduction at the membrane

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

Allosteric gating of Son of sevenless activity by the histone domain

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

Role of the histone domain in the autoinhibition and activation of the Ras activator Son of Sevenless

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

Bayesian detection of intensity changes in single molecule and molecular dynamics trajectories

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

Cell signaling in space and time: where proteins come together and when they're apart

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

The role of dynamic conformational ensembles in biomolecular recognition

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

The origin of allosteric functional modulation: multiple pre-existing pathways

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

Digital signaling and hysteresis characterize ras activation in lymphoid cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

A stochastic single-molecule event triggers phenotype switching of a bacterial cell

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

Using plasma membrane nanoclusters to build better signaling circuits

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

Membrane-dependent signal integration by the Ras activator Son of sevenless

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

Fluorescence imaging of membrane dynamics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

Dynamic personalities of proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

A hierarchy of timescales in protein dynamics is linked to enzyme catalysis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

An interpretation of fluctuations in enzyme catalysis rate, spectral diffusion, and radiative component of lifetimes in terms of electric field fluctuations

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

GEFs and GAPs: critical elements in the control of small G proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

Phospholipase D2-generated phosphatidic acid couples EGFR stimulation to Ras activation by Sos.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

Unusual interplay of two types of Ras activators, RasGRP and SOS, establishes sensitive and robust Ras activation in lymphocytes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

Compartmentalized Ras/MAPK signaling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

Ever-fluctuating single enzyme molecules: Michaelis-Menten equation revisited

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

Observation of a Power-Law Memory Kernel for Fluctuations within a Single Protein Molecule

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

Structural analysis of autoinhibition in the Ras activator Son of sevenless

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

Structural evidence for feedback activation by Ras.GTP of the Ras-specific nucleotide exchange factor SOS

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

Single-molecule enzymatic dynamics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

Evolution of enzyme function and the development of catalytic efficiency

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255705

Gain-of-function SOS1 mutations cause a distinctive form of Noonan syndrome.

7 July 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250373

From molecular noise to behavioural variability in a single bacterium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250373

Direct observation of ligand recognition by T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250373

A general method for numerically simulating the stochastic time evolution of coupled chemical reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250373

Using patterned supported lipid membranes to investigate the role of receptor organization in intercellular signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250373

Computational docking and solution x-ray scattering predict a membrane-interacting role for the histone domain of the Ras activator son of sevenless

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250373

B- and C-RAF display essential differences in their binding to Ras: the isotype-specific N terminus of B-RAF facilitates Ras binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250373

Synthesis of functional Ras lipoproteins and fluorescent derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250373

Synthesis of palmitoylated Ras-peptides and -proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250373

Monitoring lipid anchor organization in cell membranes by PIE-FCCS

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250373

Resolving heterogeneity on the single molecular level with the photon-counting histogram

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250373

Single-molecule Michaelis-Menten equations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250373

Structure and dynamics of the full-length lipid-modified H-Ras protein in a 1,2-dimyristoylglycero-3-phosphocholine bilayer

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250373

Molecular dynamics simulation of a bilayer of 200 lipids in the gel and in the liquid crystal phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250373

A Ras-induced conformational switch in the Ras activator Son of sevenless

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250373

Sending signals dynamically

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250373

Dynamic activation of an allosteric regulatory protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250373

Protein activity regulation by conformational entropy

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250373

Internal dynamics control activation and activity of the autoinhibited Vav DH domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250373

Differences in flexibility underlie functional differences in the Ras activators son of sevenless and Ras guanine nucleotide releasing factor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250373

Slow Transitions and Hysteretic Behavior in Enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250373

Reversible stages of the low-pH-triggered conformational change in influenza virus hemagglutinin

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250373

Spatio-temporal segregation of Ras signals: one ship, three anchors, many harbors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250373

Paradigm Shift of the Plasma Membrane Concept from the Two-Dimensional Continuum Fluid to the Partitioned Fluid: High-Speed Single-Molecule Tracking of Membrane Molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250373

Single-molecule imaging analysis of Ras activation in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250373

Ras plasma membrane signalling platforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250373

Ras nanoclusters: molecular structure and assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250373

Rasosomes spread Ras signals from plasma membrane 'hotspots'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1250373

Micropatterning fluid lipid bilayers on solid supports

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24994643

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Regulation of ras signaling dynamics by Sos-mediated positive feedback

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24994643

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCIENCE.1250373

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24994643%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24994643%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

24994643

1 reference