(Q34632169)

3 August 2017

title

BikDD eliminates breast cancer initiating cells and synergizes with lapatinib for breast cancer treatment (English)

1 reference

3 August 2017

1 reference

Xiaoming Xie

8

0 references

Wendy A Woodward

object named as

Wendy A Woodward

9

0 references

Funda Meric-Bernstam

3

object named as

Funda Meric-Bernstam

1 reference

3 August 2017

11

Gabriel N Hortobagyi

1 reference

3 August 2017

12

Mien-Chie Hung

1 reference

3 August 2017

7

Hirohito Yamaguchi

1 reference

3 August 2017

Jing-Yu Lang

1

1 reference

3 August 2017

Jennifer L Hsu

2

1 reference

3 August 2017

Chun-Ju Chang

4

1 reference

3 August 2017

Qingfei Wang

5

1 reference

3 August 2017

Yi Bao

6

1 reference

3 August 2017

Dihua Yu

10

1 reference

3 August 2017

publication date

1 September 2011

1 reference

3 August 2017

1 reference

3 August 2017

volume

20

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3 August 2017

issue

3

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3 August 2017

page(s)

341-356

1 reference

Eradication of chemotherapy-resistant CD44+ human ovarian cancer stem cells in mice by intraperitoneal administration of Clostridium perfringens enterotoxin

3 August 2017

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7 July 2018

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Cancer targeted gene therapy of BikDD inhibits orthotopic lung cancer growth and improves long-term survival

7 July 2018

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Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics

7 July 2018

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Resistance to paclitaxel therapy is related with Bcl-2 expression through an estrogen receptor mediated pathway in breast cancer.

7 July 2018

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7 July 2018

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7 July 2018

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Lapatinib resistance in HCT116 cells is mediated by elevated MCL-1 expression and decreased BAK activation and not by ERBB receptor kinase mutation

7 July 2018

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7 July 2018

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7 July 2018

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let-7 regulates self renewal and tumorigenicity of breast cancer cells

7 July 2018

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Noxa up-regulation and Mcl-1 cleavage are associated to apoptosis induction by bortezomib in multiple myeloma

7 July 2018

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Myeloid cell leukemia-1 inversely correlates with glycogen synthase kinase-3beta activity and associates with poor prognosis in human breast cancer.

7 July 2018

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Expression of p95HER2, a truncated form of the HER2 receptor, and response to anti-HER2 therapies in breast cancer.

7 July 2018

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Lapatinib plus capecitabine for HER2-positive advanced breast cancer

7 July 2018

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A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

7 July 2018

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Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma

7 July 2018

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The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized.

7 July 2018

1 reference

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Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia

7 July 2018

1 reference

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Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance

7 July 2018

1 reference

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The claudin gene family: expression in normal and neoplastic tissues

7 July 2018

1 reference

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Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members

7 July 2018

1 reference

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A model of acquired autoresistance to a potent ErbB2 tyrosine kinase inhibitor and a therapeutic strategy to prevent its onset in breast cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172580

Mutant Bik expression mediated by the enhanced minimal topoisomerase IIalpha promoter selectively suppressed breast tumors in an animal model

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172580

Activity of the dual kinase inhibitor lapatinib (GW572016) against HER-2-overexpressing and trastuzumab-treated breast cancer cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172580

Generation of a functional mammary gland from a single stem cell

7 July 2018

1 reference

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Purification and unique properties of mammary epithelial stem cells

7 July 2018

1 reference

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Promoting apoptosis as a strategy for cancer drug discovery

7 July 2018

1 reference

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Phase I safety, pharmacokinetics, and clinical activity study of lapatinib (GW572016), a reversible dual inhibitor of epidermal growth factor receptor tyrosine kinases, in heavily pretreated patients with metastatic carcinomas

7 July 2018

1 reference

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An inhibitor of Bcl-2 family proteins induces regression of solid tumours

7 July 2018

1 reference

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Neoadjuvant trastuzumab induces apoptosis in primary breast cancers

7 July 2018

1 reference

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Claudins 2, 3, 4, and 5 in Paget's disease and breast carcinoma

7 July 2018

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Binding at and transactivation of the COX-2 promoter by nuclear tyrosine kinase receptor ErbB-2

7 July 2018

1 reference

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Clostridium perfringens enterotoxin elicits rapid and specific cytolysis of breast carcinoma cells mediated through tight junction proteins claudin 3 and 4.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172580

Enhancement of Bik antitumor effect by Bik mutants

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172580

In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172580

Breast cancer stem cells revealed

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172580

Prospective identification of tumorigenic breast cancer cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172580

Systemic tumor suppression by the proapoptotic gene bik

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172580

The contribution of molecular markers to the prediction of response in the treatment of breast cancer: a review of the literature on HER-2, p53 and BCL-2.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172580

7 July 2018

The Hallmarks of Cancer

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Cellular survival: a play in three Akts

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172580

Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172580

Improved DNA: liposome complexes for increased systemic delivery and gene expression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172580

The Bcl-2 protein: a prognostic indicator strongly related to p53 protein in lymph node-negative breast cancer patients.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172580

Estrogen promotes chemotherapeutic drug resistance by a mechanism involving Bcl-2 proto-oncogene expression in human breast cancer cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172580

Identification of tumorsphere- and tumor-initiating cells in HER2/Neu-induced mammary tumors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172580

Reversal of cisplatin resistance with a BH3 mimetic, (-)-gossypol, in head and neck cancer cells: role of wild-type p53 and Bcl-xL.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172580

Cancer-specific activation of the survivin promoter and its potential use in gene therapy

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172580

Hematopoietic stem cells need two signals to prevent apoptosis; BCL-2 can provide one of these, Kitl/c-Kit signaling the other

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172580

Evidence for malignant transformation in acute myeloid leukemia at the level of early hematopoietic stem cells by cytogenetic analysis of CD34+ subpopulations

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172580

Identification of human juvenile chronic myelogenous leukemia stem cells capable of initiating the disease in primary and secondary SCID mice

26 October 2018

1 reference

12 December 2020

Overexpression of BCL-x protein in primary breast cancer is associated with high tumor grade and nodal metastases

1 reference

12 December 2020

Reduced apoptosis and proliferation and increased Bcl-2 in residual breast cancer following preoperative chemotherapy

1 reference

12 December 2020

Targeted expression of BikDD eradicates pancreatic tumors in noninvasive imaging models

1 reference

12 December 2020

10.1016/J.CCR.2011.07.017

Identifiers

DOI

1 reference

3 August 2017

1 reference

3 August 2017

1 reference