(Q34649752)

3 August 2017

From obesity genetics to the future of personalized obesity therapy (English)

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3 August 2017

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Philippe Froguel

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author name string

Julia S El-Sayed Moustafa

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1

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3 August 2017

26 March 2013

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Nature Reviews Endocrinology

3 August 2017

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3 August 2017

9

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3 August 2017

7

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3 August 2017

402-413

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https://scigraph.springernature.com/pub.10.1038/nrendo.2013.57

3 August 2017

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1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Role of melanocortinergic neurons in feeding and the agouti obesity syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

A war on obesity, not the obese.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Body weight in the Finnish Twin Cohort

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

A twin study of human obesity.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

The Body-Mass Index of Twins Who Have Been Reared Apart

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

An Adoption Study of Human Obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Genetic and environmental factors in relative body weight and human adiposity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Evidence for a strong genetic influence on childhood adiposity despite the force of the obesogenic environment

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Modification effects of physical activity and protein intake on heritability of body size and composition

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Investigation of Mendelian forms of obesity holds out the prospect of personalized medicine

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Human genetics illuminates the paths to metabolic disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Is obesity our genetic legacy?

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

The genetic contribution to non-syndromic human obesity

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Obese, a new mutation in the house mouse

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Positional cloning of the mouse obese gene and its human homologue

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

A nutrient-sensing pathway regulates leptin gene expression in muscle and fat.

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

The stomach is a source of leptin

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Localization of leptin receptor mRNA splice variants in murine peripheral tissues by RT-PCR and in situ hybridization

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Leptin and leptin receptor mRNA and protein expression in the murine fetus and placenta

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Identification and expression cloning of a leptin receptor, OB-R

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Abnormal splicing of the leptin receptor in diabetic mice

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Diabetes, a New Mutation in the Mouse

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

The influence of genetic background on expression of mutations at the diabetes locus in the mouse. I. C57BL/KsJ and C57BL/6J strains

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

High prevalence of leptin and melanocortin-4 receptor gene mutations in children with severe obesity from Pakistani consanguineous families.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Congenital leptin deficiency due to homozygosity for the Delta133G mutation: report of another case and evaluation of response to four years of leptin therapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Leptin replacement improves cognitive development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Congenital leptin deficiency is associated with severe early-onset obesity in humans

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

A leptin missense mutation associated with hypogonadism and morbid obesity.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Monogenic obesity in humans

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Leptin: a pivotal regulator of human energy homeostasis

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Effects of recombinant leptin therapy in a child with congenital leptin deficiency.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Clinical and molecular genetic spectrum of congenital deficiency of the leptin receptor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Homozygosity for a novel missense mutation in the leptin receptor gene (P316T) in two Egyptian cousins with severe early onset obesity.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Pro-opiomelanocortin processing in the hypothalamus: impact on melanocortin signalling and obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Implications of proopiomelanocortin (POMC) mutations in humans: the POMC deficiency syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

A missense mutation disrupting a dibasic prohormone processing site in pro-opiomelanocortin (POMC) increases susceptibility to early-onset obesity through a novel molecular mechanism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Heterozygous mutations causing partial prohormone convertase 1 deficiency contribute to human obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Small-intestinal dysfunction accompanies the complex endocrinopathy of human proprotein convertase 1 deficiency

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Hyperphagia and early-onset obesity due to a novel homozygous missense mutation in prohormone convertase 1/3.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Mutational analysis of melanocortin-4 receptor, agouti-related protein, and α-melanocyte-stimulating hormone genes in severely obese children

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Prevalence of melanocortin-4 receptor deficiency in Europeans and their age-dependent penetrance in multigenerational pedigrees.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Melanocortin 4 receptor mutations in a large cohort of severely obese adults: prevalence, functional classification, genotype-phenotype relationship, and lack of association with binge eating

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Profound obesity associated with a balanced translocation that disrupts the SIM1 gene

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

SIM1 overexpression partially rescues agouti yellow and diet-induced obesity by normalizing food intake.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Sim1 gene dosage modulates the homeostatic feeding response to increased dietary fat in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Development of neuroendocrine lineages requires the bHLH-PAS transcription factor SIM1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Sim1 haploinsufficiency causes hyperphagia, obesity and reduction of the paraventricular nucleus of the hypothalamus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Deletion of the SIM1 gene (6q16.2) in a patient with a Prader-Willi-like phenotype

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

The human obesity gene map: the 2005 update

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Meta-Analysis of Genome-wide Linkage Studies in BMI and Obesity*

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

A genomewide linkage scan for quantitative-trait loci for obesity phenotypes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Tests of linkage and/or association of the LEPR gene polymorphisms with obesity phenotypes in Caucasian nuclear families

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

A major predisposition locus for severe obesity, at 4p15-p14

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Genetic linkage and imprinting effects on body mass index in children and young adults

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Quantitative trait loci for abdominal fat and BMI in Hispanic-Americans and African-Americans: the IRAS Family study.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

A genome-wide linkage scan for body mass index on Framingham Heart Study families

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Quantitative trait locus determining dietary macronutrient intakes is located on human chromosome 2p22

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

A whole-genome scan for obstructive sleep apnea and obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

The quantitative trait locus on chromosome 2 for serum leptin levels is confirmed in African-Americans

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

A follow-up linkage study for quantitative trait loci contributing to obesity-related phenotypes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Genome-Wide Linkage to Chromosome 6 for Waist Circumference in the Framingham Heart Study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

A combined analysis of genomewide linkage scans for body mass index from the National Heart, Lung, and Blood Institute Family Blood Pressure Program

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Linkage for BMI at 3q27 region confirmed in an African-American population.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

A genome-wide scan for coronary heart disease suggests in Indo-Mauritians a susceptibility locus on chromosome 16p13 and replicates linkage with the metabolic syndrome on 3q27.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

An autosomal genomic scan for loci linked to plasma leptin concentration in Pima Indians

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Quantitative trait loci on chromosomes 3 and 17 influence phenotypes of the metabolic syndrome.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Genomewide search for type 2 diabetes-susceptibility genes in French whites: evidence for a novel susceptibility locus for early-onset diabetes on chromosome 3q27-qter and independent replication of a type 2-diabetes locus on chromosome 1q21-q24.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Genomewide linkage analysis of body mass index across 28 years of the Framingham Heart Study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

A genome-wide scan for childhood obesity-associated traits in French families shows significant linkage on chromosome 6q22.31-q23.2.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Quantitative-trait loci influencing body-mass index reside on chromosomes 7 and 13: the National Heart, Lung, and Blood Institute Family Heart Study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

A Genome-Wide Scan for Abdominal Fat Assessed by Computed Tomography in the Quebec Family Study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

A locus affecting obesity in human chromosome region 10p12.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

A genome-wide scan for human obesity genes reveals a major susceptibility locus on chromosome 10

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Independent confirmation of a major locus for obesity on chromosome 10.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

An autosomal genomic scan for loci linked to type II diabetes mellitus and body-mass index in Pima Indians

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Autosomal genomic scan for loci linked to obesity and energy metabolism in Pima Indians

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Interacting genetic loci on chromosomes 20 and 10 influence extreme human obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Linkage of body mass index to chromosome 20 in Utah pedigrees.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Genome scan for human obesity and linkage to markers in 20q13.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

The V103I polymorphism of the MC4R gene and obesity: population based studies and meta-analysis of 29 563 individuals

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Non-synonymous polymorphisms in melanocortin-4 receptor protect against obesity: the two facets of a Janus obesity gene

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Association of the 103I MC4R allele with decreased body mass in 7937 participants of two population based surveys

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Melanocortin-4 receptor gene and physical activity in the Québec Family Study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Melanocortin-4 receptor gene variant I103 is negatively associated with obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Melanocortin 4 receptor gene variation is associated with severe obesity in Pima Indians

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Melanocortin-4 receptor gene: case-control study and transmission disequilibrium test confirm that functionally relevant mutations are compatible with a major gene effect for extreme obesity.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Linkage and association studies between the melanocortin receptors 4 and 5 genes and obesity-related phenotypes in the Québec Family Study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Serum brain-derived neurotrophic factor concentrations in lean and overweight children and adolescents

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Association of BDNF with restricting anorexia nervosa and minimum body mass index: a family-based association study of eight European populations.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Hyperphagia, severe obesity, impaired cognitive function, and hyperactivity associated with functional loss of one copy of the brain-derived neurotrophic factor (BDNF) gene

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Two British women studies replicated the association between the Val66Met polymorphism in the brain-derived neurotrophic factor (BDNF) and BMI.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Common nonsynonymous variants in PCSK1 confer risk of obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

The ADRB3 Trp64Arg variant and BMI: a meta-analysis of 44 833 individuals

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Meta-analysis of the association of the Trp64Arg polymorphism in the beta3 adrenergic receptor with body mass index

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Genetic variation in the beta 3-adrenergic receptor and an increased capacity to gain weight in patients with morbid obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Association of BMI with the beta3-adrenergic receptor gene polymorphism in Japanese: meta-analysis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Association of Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma with Pre-diabetic phenotypes: meta-analysis of 57 studies on nondiabetic individuals.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Obesity associated with a mutation in a genetic regulator of adipocyte differentiation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Recent progress in the genetics of common obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Variation in FTO contributes to childhood obesity and severe adult obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

A genome-wide association meta-analysis identifies new childhood obesity loci

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

FTO variants are associated with obesity in the Chinese and Malay populations in Singapore

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Replication of 13 obesity loci among Singaporean Chinese, Malay and Asian-Indian populations.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Genome-wide population-based association study of extremely overweight young adults--the GOYA study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Genetic variants in FTO associated with metabolic syndrome: a meta- and gene-based analysis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Genome-wide association study of height and body mass index in Australian twin families

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Common variants near MC4R are associated with fat mass, weight and risk of obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Common body mass index-associated variants confer risk of extreme obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Common genetic variation near MC4R is associated with waist circumference and insulin resistance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

A genome-wide association study on obesity and obesity-related traits

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Developments in obesity genetics in the era of genome-wide association studies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Global variation in copy number in the human genome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Paired-end mapping reveals extensive structural variation in the human genome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Array CGH analysis of copy number variation identifies 1284 new genes variant in healthy white males: implications for association studies of complex diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Origins and functional impact of copy number variation in the human genome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Genome-wide association study suggested copy number variation may be associated with body mass index in the Chinese population

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Novel common copy number variation for early onset extreme obesity on chromosome 11q11 identified by a genome-wide analysis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

A new highly penetrant form of obesity due to deletions on chromosome 16p11.2.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Large, rare chromosomal deletions associated with severe early-onset obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Large copy-number variations are enriched in cases with moderate to extreme obesity.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Age- and gender-dependent obesity in individuals with 16p11.2 deletion.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Association between microdeletion and microduplication at 16p11.2 and autism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Microduplications of 16p11.2 are associated with schizophrenia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Neuronal SH2B1 is essential for controlling energy and glucose homeostasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Human SH2B1 mutations are associated with maladaptive behaviors and obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

A genome-wide study reveals copy number variants exclusive to childhood obesity cases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Novel association approach for variable number tandem repeats (VNTRs) identifies DOCK5 as a susceptibility gene for severe obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Genome-wide association studies: theoretical and practical concerns

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Genetic determinants of common obesity and their value in prediction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Estimation of newborn risk for child or adolescent obesity: lessons from longitudinal birth cohorts

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Prader-Willi and Angelman syndromes: sister imprinted disorders

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Association of FTO gene variants with body composition in UK twins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Associations of markers in 11 obesity candidate genes with maximal weight loss and weight regain in the SOS bariatric surgery cases.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

High allelic burden of four obesity SNPs is associated with poorer weight loss outcomes following gastric bypass surgery

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Bariatric surgery in a patient with complete MC4R deficiency

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Weight loss after Roux-en-Y gastric bypass in obese patients heterozygous for MC4R mutations

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Melanocortin-4 receptor signaling is required for weight loss after gastric bypass surgery

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Melanocortin-4 receptor mutations and polymorphisms do not affect weight loss after bariatric surgery

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Finding the missing heritability of complex diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Molecular diagnosis of neonatal diabetes mellitus using next-generation sequencing of the whole exome.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Whole-exome sequencing and high throughput genotyping identified KCNJ11 as the thirteenth MODY gene

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

De novo mutations of SETBP1 cause Schinzel-Giedion syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

De novo mutations revealed by whole-exome sequencing are strongly associated with autism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Patterns and rates of exonic de novo mutations in autism spectrum disorders

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

KCTD13 is a major driver of mirrored neuroanatomical phenotypes of the 16p11.2 copy number variant

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

LocusZoom: regional visualization of genome-wide association scan results

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.57

Genomewide search for genes influencing percent body fat in Pima Indians: suggestive linkage at chromosome 11q21-q22. Pima Diabetes Gene Group

31 March 2020

1 reference

12 December 2020

Use of the robust sib-pair method to screen for single-locus, multiple-locus, and pleiotropic effects: application to traits related to hypertension

1 reference

12 December 2020

Human leptin deficiency caused by a missense mutation: multiple endocrine defects, decreased sympathetic tone, and immune system dysfunction indicate new targets for leptin action, greater central than peripheral resistance to the effects of leptin,

1 reference

12 December 2020

Genome-wide association studies of obesity and metabolic syndrome

1 reference

12 December 2020

Genome-wide scan of obesity in the Old Order Amish

1 reference

12 December 2020

FTO, obesity and the adolescent brain

1 reference

12 December 2020

Meta-analysis of the association of Trp64Arg polymorphism of beta 3-adrenergic receptor gene with body mass index.

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRENDO.2013.57

1 reference

PubMed ID

23529041

Dimensions Publication ID

3 August 2017

0 references

1 reference

PubMed ID

23529041