(Q34658518)

3 August 2017

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title

Cytokine control of developmental programs in normal hematopoiesis and leukemia (English)

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3 August 2017

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Joseph Lotem

1

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3 August 2017

Leo Sachs

series ordinal

2

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3 August 2017

language of work or name

English

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publication date

1 May 2002

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3 August 2017

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3 August 2017

21

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3 August 2017

3284-3294

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3 August 2017

21

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1205319

3 August 2017

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cites work

Regulation of p53-mediated apoptosis and cell cycle arrest by Steel factor

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Regulation of the human hsp70 promoter by p53

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Hepatocytes from non-hepatic adult stem cells

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Turning brain into blood: a hematopoietic fate adopted by adult neural stem cells in vivo

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Developmental changes in the differentiation capacity of haematopoietic stem cells.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

The growth of mouse bone marrow cells in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Growth factor modulation of p53-mediated growth arrest versus apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Cytokine-regulated expression of survivin in myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

mcl-1 is an immediate-early gene activated by the granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling pathway and is one component of the GM-CSF viability response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Apaf-1/cytochrome c-independent and Smac-dependent induction of apoptosis in multiple myeloma (MM) cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

The human hematopoietic colony-stimulating factors

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Thymocyte apoptosis induced by p53-dependent and independent pathways.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Interleukin 3 protects murine bone marrow cells from apoptosis induced by DNA damaging agents

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Cellular survival: a play in three Akts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

All‐trans‐retinoic acid treatment and retinoic acid receptor alpha gene rearrangement in acute promyelocytic leukemia: A model for differentiation therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

IAP family proteins--suppressors of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Distinct cytoplasmic regions of the human granulocyte colony-stimulating factor receptor involved in induction of proliferation and maturation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

The gene encoding p202, an interferon-inducible negative regulator of the p53 tumor suppressor, is a target of p53-mediated transcriptional repression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Qualitative and quantitative aspects of haematopoietic cell development in the mammalian embryo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Hematopoietic cells differentiate into both microglia and macroglia in the brains of adult mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Differentiation of leukemia cells to polymorphonuclear leukocytes in patients with acute nonlymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Normal Differentiation of Myeloid Leukaemic Cells induced by a Differentiation-inducing Protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Control of Normal Differentiation of Myeloid Leukemic Cells to Macrophages and Granulocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Control of normal differentiation of myeloid leukemic cells. XI. Induction of a specific requirement for cell viability and growth during the differentiation of myeloid leukemic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Growth and differentiation signals mediated by different regions in the cytoplasmic domain of granulocyte colony-stimulating factor receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Recent developments in the regulation of peripheral blood stem cell mobilization and engraftment by cytokines, chemokines, and adhesion molecules

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Regulation of the induction of colonies in vitro by normal human lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Expression of myb, myc and fos proto-oncogenes during the differentiation of a murine myeloid leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Participation of myeloid leukaemic cells injected into embryos in haematopoietic differentiation in adult mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

The future of cloning

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Mdm2 promotes the rapid degradation of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Interleukin-6- and leukemia inhibitory factor-induced terminal differentiation of myeloid leukemia cells is blocked at an intermediate stage by constitutive c-myc

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Control mechanisms regulating gene expression during normal differentiation of myeloid leukemic cells: differentiation defective mutants blocked in mRNA production and mRNA translation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Combination of stem cell factor and granulocyte colony-stimulating factor mobilizes the highest number of primitive haemopoietic progenitors as shown by pre-colony-forming unit (pre-CFU) assay.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Interleukin 3 mediates interleukin 6 production in murine interleukin 3-dependent hemopoietic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

In vitro control of the development of macrophage and granulocyte colonies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Feedback inhibition of the development of macrophage and granulocyte colonies. I. Inhibition by macrophage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Cytokine receptor signalling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Hematopoietic potential of stem cells isolated from murine skeletal muscle

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

DNA microarray analysis of genes involved in p53 mediated apoptosis: activation of Apaf-1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Thrombopoietin: the primary regulator of platelet production [see comments]

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

A common precursor for primitive erythropoiesis and definitive haematopoiesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Withdrawal of IL-7 induces Bax translocation from cytosol to mitochondria through a rise in intracellular pH.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Cytokine signal transduction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

p53: puzzle and paradigm

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Interleukin-6 protects against Fas-mediated death by establishing a critical level of anti-apoptotic hepatic proteins FLIP, Bcl-2, and Bcl-xL.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Regulation of p53 stability by Mdm2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Purified hematopoietic stem cells can differentiate into hepatocytes in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Characterization of the inducer required for the development of macrophage and granulocyte colonies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

p53, the cellular gatekeeper for growth and division

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Molecular dissection of differentiation in normal and leukemic myeloblasts: separately programmed pathways of gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Pidd, a new death-domain-containing protein, is induced by p53 and promotes apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Cellular oxidative stress and the control of apoptosis by wild-type p53, cytotoxic compounds, and cytokines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Different Blocks in the Differentiation of Myeloid Leukemic Cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Genetic dissection of the control of normal differentiation in myeloid leukemic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

In vivo induction of normal differentiation in myeloid leukemia cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

In vivo inhibition of the development of myeloid leukemia by injection of macrophage- and granulocyte-inducing protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Mechanisms that uncouple growth and differentiation in myeloid leukemia cells: restoration of requirement for normal growth-inducing protein without restoring induction of differentiation-inducing protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Coupling of growth and differentiation in normal myeloid precursors and the breakdown of this coupling in leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Control of in vivo differentiation of myeloid leukemic cells. IV. Inhibition of leukemia development by myeloid differentiation-inducing protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Regulation of cell-surface receptors for hematopoietic differentiation-inducing protein MGI-2 on normal and leukemic myeloid cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Indirect induction of differentiation of normal and leukemic myeloid cells by recombinant interleukin 1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

A mutant p53 antagonizes the deregulated c-myc-mediated enhancement of apoptosis and decrease in leukemogenicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Differential suppression by protease inhibitors and cytokines of apoptosis induced by wild-type p53 and cytotoxic agents

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Cytokine suppression of protease activation in wild-type p53-dependent and p53-independent apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Different mechanisms for suppression of apoptosis by cytokines and calcium mobilizing compounds

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Cytokines as suppressors of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

p53 is required for radiation-induced apoptosis in mouse thymocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Molecular cloning of a ligand for the flt3/flk-2 tyrosine kinase receptor: a proliferative factor for primitive hematopoietic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Interleukin-15 prevents mouse mast cell apoptosis through STAT6-mediated Bcl-xL expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Interferons and interleukin-6 suppress the DNA-binding activity of E2F in growth-sensitive hematopoietic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

The granulocyte-macrophage colony-stimulating factors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Growth of B-lymphocyte colonies in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Apaf-1 is a transcriptional target for E2F and p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Structure and function of a new STAT-induced STAT inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

PUMA, a novel proapoptotic gene, is induced by p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

p53DINP1, a p53-inducible gene, regulates p53-dependent apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Bone marrow cells regenerate infarcted myocardium

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

The single cell origin of normal granulocyte coloniesin vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

In vitro induction of granulocyte differentiation in hematopoietic cells from leukemic and non-leukemic patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Bone marrow as a potential source of hepatic oval cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Human bone marrow colony growth in agar-gel

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

The cloning of normal ?Mast? cells in tissue culture

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

The induction of clones of normal mast cells by a substance from conditioned medium

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

The insulin-like growth factor I receptor as a physiologically relevant target of p53 in apoptosis caused by interleukin-3 withdrawal.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

A New Type of Cytokine Receptor Antagonist Directly Targeting gp130

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Control of normal cell differentiation and the phenotypic reversion of malignancy in myeloid leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Growth, differentiation and the reversal of malignancy.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

The Wellcome Foundation lecture, 1986. The molecular regulators of normal and leukaemic blood cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

The molecular control of blood cell development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

The control of growth and differentiation in normal and leukemic blood cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

The control of hematopoiesis and leukemia: from basic biology to the clinic

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Interleukin 3-dependent activation of DREAM is involved in transcriptional silencing of the apoptotic Hrk gene in hematopoietic progenitor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Deregulated c-myb disrupts interleukin-6- or leukemia inhibitory factor-induced myeloid differentiation prior to c-myc: role in leukemogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Autoregulation of interleukin 6 and granulocyte-macrophage colony-stimulating factor in the differentiation of myeloid leukemic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Downregulation of Bim, a proapoptotic relative of Bcl-2, is a pivotal step in cytokine-initiated survival signaling in murine hematopoietic progenitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

A transcription factor party during blood cell differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

A family of cytokine-inducible inhibitors of signalling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Induction of colonies of hemoglobin-synthesizing cells by erythropoietin in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

DNA damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by Bcl-2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Gp130 and the interleukin-6 family of cytokines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Cytokine signaling through nonreceptor protein tyrosine kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Liver from bone marrow in humans.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Apoptosis in the pathogenesis and treatment of disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Outer mitochondrial membrane permeability can regulate coupled respiration and cell survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Bcl-xL prevents cell death following growth factor withdrawal by facilitating mitochondrial ATP/ADP exchange

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Bcl-xL promotes the open configuration of the voltage-dependent anion channel and metabolite passage through the outer mitochondrial membrane

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Developmental potential of myeloid leukemia cells injected into midgestation embryos.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

1 reference

7 January 2021

Gastrointestinal cells of IL-7 receptor null mice exhibit increased sensitivity to irradiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Steel locus defines new multipotent growth factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

PUMA induces the rapid apoptosis of colorectal cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Ciliary neurotropic factor, interleukin 11, leukemia inhibitory factor, and oncostatin M are growth factors for human myeloma cell lines using the interleukin 6 signal transducer gp130

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205319

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205319

1 reference

Dimensions Publication ID

3 August 2017

0 references

1 reference