(Q34674685)

3 August 2017

1 reference

title

Apoptosis and age-related disorders: role of caspase-dependent and caspase-independent pathways (English)

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3 August 2017

Pierluigi Nicotera

1

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3 August 2017

1 February 2002

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3 August 2017

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3 August 2017

127

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3 August 2017

1-3

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3 August 2017

189-195

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Selective induction of apoptosis in Hep 3B cells by topoisomerase I inhibitors: evidence for a protease-dependent pathway that does not activate cysteine protease P32.

3 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Apoptosis without caspases: an inefficient molecular guillotine?

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Characterization of progressive motor deficits in mice transgenic for the human Huntington's disease mutation.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Apoptotic features of selective neuronal death in ischemia, epilepsy and gp 120 toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Cleavage of atrophin-1 at caspase site aspartic acid 109 modulates cytotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Prolonged therapeutic window for ischemic brain damage caused by delayed caspase activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Neurotoxicity of a prion protein fragment.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Apoptosis-mediated neurotoxicity induced by beta-amyloid and PrP fragments.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

The central executioners of apoptosis: caspases or mitochondria?

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Proteasomes play an essential role in thymocyte apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Transgenic mice expressing a Huntington's disease mutation are resistant to quinolinic acid-induced striatal excitotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Hsp70 exerts its anti-apoptotic function downstream of caspase-3-like proteases.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Aggresomes: a cellular response to misfolded proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Mutant huntingtin expression in clonal striatal cells: dissociation of inclusion formation and neuronal survival by caspase inhibition.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Caspase-3 cleaves the expanded androgen receptor protein of spinal and bulbar muscular atrophy in a polyglutamine repeat length-dependent manner

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

ICE-protease inhibitors block murine liver injury and apoptosis caused by CD95 or by TNF-alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Turnover of bacterial glutamine synthetase: oxidative inactivation precedes proteolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Excitatory amino acids as a final common pathway for neurologic disorders.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Inhibition of Ced-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue Bak

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Expression of extended polyglutamine sequentially activates initiator and effector caspases

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Caspases: killer proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Apoptosis: cell death defined by caspase activation

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Caspase-8 is required for cell death induced by expanded polyglutamine repeats.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Target cell lysis by CTL granule exocytosis is independent of ICE/Ced-3 family proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Caspase inhibition reduces apoptosis and increases survival of nigral transplants.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Caspases as treatment targets in stroke and neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Programmed cell death, apoptosis and killer genes

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Do all programmed cell deaths occur via apoptosis?

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Developing Caenorhabditis elegans neurons may contain both cell-death protective and killer activities

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Mitochondrial encephalomyopathies

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

The central executioner of apoptosis: multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Identification of caspases that cleave presenilin-1 and presenilin-2

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Apoptosis in caspase-inhibited neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Proteolytic processing of the Alzheimer's disease amyloid precursor protein within its cytoplasmic domain by caspase-like proteases.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Constitutive expression of the machinery for programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

BAX-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

The Caenorhabditis elegans genes ced-3 and ced-4 act cell autonomously to cause programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900500-8

7 January 2021

10.1016/S0378-4274(01)00500-8

Identifiers

DOI

1 reference

3 August 2017

1 reference

PubMed ID

12052658